protosappanin A

Name: protosappanin A
Brand: Biopurify
Rating: 5 (1 reviews)

Catalogue No.： BP3329

CAS NO.: 102036-28-2

Purity: 98%

Brand: Biopurify

Protosappanin A has anti-oxidative/nitrative activities on brain immune and neuroinflammation through regulation of CD14/TLR4-dependent IKK/IκB/NF-κB inflammation signal pathway; it exerts anti-neuroinflammatory effect by inhibiting JAK2-STAT3 pathway in lipopolysaccharide-induced BV2 microglia. Protosappanin A induces immunosuppression of rats heart transplantation targeting T cells in grafts via NF-kappaB pathway. Protosappanin A and protosappanin B have antimicrobial activity, they show both alone activities and resistance reversal effects of amikacin and gentamicin against MRSA. Protosappanin A shows strong effect against HIV-1 IN with an IC50 value of 12.6 uM. Protosappanin A is a member of catechols. It has a role as a metabolite.

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BP3329-10mg	10mg	Sign in	Sign in
BP3329-20mg	20mg	Sign in	Sign in
BP3329-100mg	100mg	Sign in	Sign in

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Related diseases

Cardiovascular disease Inflammatory disease Antitumor Autoimmune disease Neurodegenerative disease

Related targets

Cardiovascular disease BCL2 STAT3 TOP1 RELA TNF NOS2 PTGS2 CASP3 IL6 ICAM1 VCAM1 BAX

Inflammatory disease STAT3 RELA TNF NOS2 PTGS2 IL6 ICAM1 JAK2

Antitumor BCL2 STAT3 TOP1 TOP2A PTGS2 TP53 CASP3 JAK2 BAX

Autoimmune disease BCL2 STAT3 RORC RELA TNF NOS2 PTGS2 IL6 JAK2 IFNG IL17A

Neurodegenerative disease BCL2 STAT3 RELA TNF NOS2 PTGS2 CASP3 IL6 ICAM1 BAX

Product description Related Products Prediction Parameters Reference Literature

Product name: protosappanin A
Synonym name:
Catalogue No.: BP3329
Cas No.: 102036-28-2
Formula: C₁₅H₁₂O₅
Mol Weight: 272.256
Botanical Source:
Physical Description:
Type of Compound: Miscellaneous

Purity: 95%~99%
Analysis Method: HPLC-DAD or/and HPLC-ELSD
Identification Method: Mass, NMR
Packing: Brown vial or HDPE plastic bottle
The product could be supplied from milligrams to grams. Inquire for bulk scale.
We provide solution to improve the water-solubility of compounds, thereby facilitating the variety of activity tests and clinic uses.

For Reference Standard and R&D, Not for Human Use Directly.