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Tumor Angiogenesis-related Diseases

Catalog No Product Description CAS No. Purity Structural Formula
BP0339
Chebulinic acid
Chebulinic acid is a potent natural inhibitor of M. tuberculosis DNA gyrase, also can inhibit SMAD-3 phosphorylation, inhibit H+ K+-ATPase activity; it also is a natural inhibitor of vascular endothelial growth factor-A mediated angiogenesis. Chebulinic acid has hypotensive, antioxidant, anti-HIV, and anti-ulcer activities. Chebulinic acid has inhibitory effect on erythroid differentiation likely through changing transcriptional activation of differentiation relative genes, it or other tannins might influence the efficiency of some anti-tumor drugs-induced differentiation or the hematopoiesis processes.
18942-26-2 98% Chebulinic acid
BP0875
Liquiritin apioside
Liquiritin apioside has antioxidant property by inducing glutathione (GSH) biosynthesis via the inhibition of cytokines and protected lung epithelial cells against cigarette smoke-mediated oxidative stress, might be as protective agent against epithelial injury in COPD. Liquiritin apioside is a glycoside and a member of flavonoids.
74639-14-8 98% Liquiritin apioside
BP5028
Sinomenine N-oxide
Sinomenine shows neuroprotective, anti- rheumatoid arthritis, anti-inflammatory and immunosuppressive effects, it can attenuate 2, 4, 6-trinitrobenzene sulfonic acid (TNBS)-induced colitis in mice and the therapeutic mechanism may be related to the reduction of up-regulated colonic TNF-alpha and IFN-gamma production caused by TNBS. Sinomenine also provides a novel therapy to treat ICH induced brain injury. Sinomenine can prevent galactosamine (GalN)/lipopolysaccharide (LPS) -treated hepatic failure by suppressing TNF production and/or reactive oxygen generation.
1000026-77-6 98% Sinomenine N-oxide
SBP00170
4-Hydroxybenzyl alcohol
4-Hydroxybenzyl alcohol possesses anti-angiogenic, anti-inflammatory and anti- nociceptive activity possibly via its down-regulating activity on NO production, which may be partly responsible for the pharmacological efficacy of several folkloric medicines. It exhibits beneficial effects in cerebral ischemic injury, has neuroprotective effect through upregulation of Nrf2, Prdx6, and PDI expression via the PI3K/Akt pathway. P-hydroxybenzyl alcohol is a member of the class of benzyl alcohols that is benzyl alcohol substituted by a hydroxy group at position 4. It has been isolated from Arcangelisia gusanlung. It has a role as a plant metabolite. It is a member of benzyl alcohols and a member of phenols.
623-05-2 98% 4-Hydroxybenzyl alcohol
BP0031
Tulipalin A
Tulipalin A is a butan-4-olide having a methylene group at the 3-position. It has a role as an anti-ulcer drug and a gastrointestinal drug.
547-65-9 98% Tulipalin A
BP4990
N-methyltyramine
N-methyltyramine is a member of tyramines. It has a role as a mouse metabolite. It is a conjugate base of a N-methyltyraminium.
370-98-9 98% N-methyltyramine