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Sedation/Anxiolysis

Sedation/anxiolysis refers to the medical practice of inducing a state of reduced anxiety, calmness, or drowsiness in a patient, typically through pharmacological agents. This state is often employed to facilitate medical procedures, alleviate distress, manage pain, or improve patient cooperation and comfort. The level of sedation can range from minimal (anxiolysis) to deep, depending on the clinical need and patient factors, with careful monitoring of vital signs and airway patency being paramount.
Catalog No Product Description CAS No. Purity Structural Formula
BP1273
Scopolamine butylbromide
Butylscopolamine bromide is an organic bromide salt of butylscopolamine. It is an antispasmodic drug which can relieve painful stomach cramps (including those linked with irritable bowel syndrome), bladder and menstrual cramps. It has a role as a muscarinic antagonist and an antispasmodic drug. It is a quaternary ammonium salt and an organic bromide salt. It contains a butylscopolamine. Scopolamine butylbromide is a competitive antagonist of muscarinic acetylcholine receptor (mAChR) with an IC50 of 55.3 ± 4.3 nM, it possesses anticholinergic, and anti-tumor effects, it used as an abdominal-specific antispasmodic agent. Scopolamine butylbromide is effective in preventing succinylcholine-induced bradycardia in infants and children.
149-64-4 98% Scopolamine butylbromide
BP1274
Scopolamine hydrobromide
Scopolamine hydrobromide is a competitive muscarinic acetylcholine receptor with an IC50 of 55.3 nM, it also reversibly inhibited the 5-HT3 receptor-responses with an IC50 of 2.09 μM. Sscopolamine hydrobromide nasal gel is a safe and promising therapeutic alternative to existing medications for motion sickness, it and NaHCO3 can be used to treat tetrodotoxin (TTX) poisoning. Scopolamine hydrobromide (anhydrous) is a hydrobromide that is obtained by reaction of scopolamine with hydrogen bromide. It has a role as a muscarinic antagonist. It contains a scopolamine(1+).
114-49-8 98% Scopolamine hydrobromide