Isoescin IB is a natural product from Aesculus hippocastanum L.

Monoxerutin is a glycoside and a member of flavonoids.

Escin Ia and Isoescin IA have been traditionally used clinically as the chief active ingredients of escin, a major triterpene saponin isolated from horse chestnut (Aesculus hippocastanum) seeds for the treatment of chronic venous insufficiency, hemorrhoids, inflammation and edema.