| Catalog No | Product Description | CAS No. | Purity | Structural Formula |
|---|---|---|---|---|
| BP4144 |
Docosahexaenoic acid
All-cis-docosa-4,7,10,13,16,19-hexaenoic acid is a docosahexaenoic acid having six cis-double bonds at positions 4, 7, 10, 13, 16 and 19. It has a role as an antineoplastic agent, a nutraceutical, a mouse metabolite, a human metabolite, a Daphnia tenebrosa metabolite and an algal metabolite. It is an omega-3 fatty acid and a docosahexaenoic acid. It is a conjugate acid of a (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate.
|
6217-54-5 | 98% |
|
| BP4018 | 146100-02-9 | 98% |
|
|
| BP1271 |
Sclareolide
Sclareolide demonstrates a good antibacterial activity against Staphylococcus aureus ATCC 25923, Pseudomonas aeruginosa ATCC 27950, Escherichia coli ATCC 25922 and Enterococcus faecalis ATCC 29212. Sclareolide enhances gemcitabine‑induced cell death through mediating the NICD and Gli1 pathways in gemcitabine‑resistant human pancreatic cancer.
|
564-20-5 | 98% |
|
| BP5286 | 2366153-27-5 | 98% |
|
|
| BP0899 |
Luteoloside
Luteolin 7-O-beta-D-glucoside is a glycosyloxyflavone that is luteolin substituted by a beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage. It has a role as an antioxidant and a plant metabolite. It is a beta-D-glucoside, a trihydroxyflavone, a glycosyloxyflavone and a monosaccharide derivative. It is functionally related to a luteolin. It is a conjugate acid of a luteolin 7-O-beta-D-glucoside(1-).
|
5373-11-5 | 98% |
|
| BP0036 |
2''-O-Galloylhyperin
2''-O-Galloylhyperin is a glycoside and a member of flavonoids.
|
53209-27-1 | 98% |
|
| BP1293 |
Sennoside B
Sennoside B is a member of the class of sennosides that is (9R,9'S)-9,9',10,10'-tetrahydro-9,9'-bianthracene-2,2'-dicarboxylic acid which is substituted by hydroxy groups at positions 4 and 4', by beta-D-glucopyranosyloxy groups at positions 5 and 5', and by oxo groups at positions 10 and 10'. It is an oxo dicarboxylic acid and a member of sennosides. Sennoside B, a major purgative component, has a potential utility in the treatment of proliferative diseases, through inhibiting PDGF-stimulated cell proliferation by binding to PDGF-BB and its receptor and by down-regulating the PDGFR-beta signaling pathway. It and sennoside A also possess significant gastroprotective activities .
|
128-57-4 | 98% |
|
| BP1347 |
Sulforaphane
Sulforaphane is a cruciferous vegetable-derived isothiocyanate with promising antitumor, chemopreventive and therapeutic activities, it inhibits TPA-induced NF-κB activation and COX-2 expression in MCF-10A cells by blocking two distinct signaling pathways mediated by ERK1/2-IKKα and NAK-IKKβ. Sulforaphane may exert a significant neuroprotective effect on cholinergic deficit and cognitive impairment, it also has anti-inflammatory effect, at least ,in part,associated with interfering with the NF-κB pathway. (R)-sulforaphane is a sulforaphane in which the sulfinyl group has R configuration. Naturally occurring compound found in brocolli that acts as a potent inducer of phase II detoxification enzymes. It is an enantiomer of a (S)-sulforaphane.
|
142825-10-3 | 98% |
|
| BP0796 |
Isorhamnetin-3-O-beta-D-Glucoside
Isorhamnetin 3-O-beta-D-glucopyranoside is a glycosyloxyflavone that is isorhamnetin substituted at position 3 by a beta-D-glucosyl residue. It has a role as a metabolite. It is a beta-D-glucoside, a monomethoxyflavone, a trihydroxyflavone, a glycosyloxyflavone and a monosaccharide derivative. It is functionally related to a beta-D-glucose and an isorhamnetin.
|
5041-82-7 | 98% |
|
| BP0687 |
Gossypol
Gossypol is an effective natural antimicrobial agent against a wide range of potential fungal pathogens of cotton.Gossypol shows a significant increase in accumulation of acidic vesicular organelle, is a promising drug that induces autophagic cell death in radioresistant malignant glioma.Gossypol binds to Bcl-xL protein and Bcl-2 protein with Kis of 0.5-0.6 μM and 0.2-0.3 mM, respectively. Gossypol is an aldehyde, a hydroxynaphthalene, a polyphenol and a hexol. It has a role as an antispermatogenic agent, an anti-inflammatory agent and a plant metabolite.
|
303-45-7 | 98% |
|
| BP5359 | 3649-76-1 | 98% |
|
|
| BP5144 | 514-66-9 | 95% |
|
|
| BP1249 |
Salvianolic acid C
Salvianolic acid C has antioxidant effect, it exhibits potent XOD inhibitory activity with an IC(50) of 9.07 μM. Salvianolic acid C enhances the inhibitory effects on sEH might be efficient ways to improve its cardiovascular protective and anti-inflammatory effects.
|
115841-09-3 | 98% |
|
| BP1486 |
Isoshaftoside
Isoschaftoside is a C-glycosyl compound that is apigenin substituted at positions 6 and 8 by alpha-L-arabinopyranosyl and beta-D-glucosyl residues respectively. It has a role as a metabolite. It is a C-glycosyl compound and a trihydroxyflavone. It is functionally related to an apigenin.
|
52012-29-0 | 98% |
|
| BP1277 |
Scutellarein
Scutellarein has antioxidant, antitumor, anti-adipogenic, antiviral and anti-inflammatory activities, it can improve neuronal injury, has better protective effect in rat cerebral ischemia. Scutellarein may serve as a SARS-CoV chemical inhibitor, it also exerts strong inhibition towards the tested UDP-glucuronosyltransferase isoforms. Scutellarein is flavone substituted with hydroxy groups at C-4', -5, -6 and -7. It has a role as a metabolite. It is functionally related to an apigenin. It is a conjugate acid of a scutellarein(1-).
|
529-53-3 | 98% |
|
| BP4659 |
Sarmentine
1-[(2E,4E)-2,4-decadienoyl]pyrrolidine is a N-acylpyrrolidine. It has a role as a metabolite.
|
78910-33-5 | 98% |
|
| BP0655 |
Ginsenoside F3
Ginsenoside F3 has immunoenhancing activity by regulating production and gene expression of type 1,type 2 cytokines in murine spleen cells. It enhances the NF-kappaB DNA binding activity induced by ConA in murine spleen cells with 10 micromol/L.
|
62025-50-7 | 98% |
|
| BP2319 |
Resveratrol 12-C-β-glucopyranoside
Resveratrol, a natural polyphenol that possesses anti-oxidant, anti-inflammatory, cardioprotective, blood-sugar-lowering, antiaging, and anti-cancer properties. It has a wide spectrum of targets including cyclooxygenases(i.e. COX, IC50=1.1 μM), lipooxygenases(LOX, IC50=2.7 μM, kinases, sirtuins, c-IAP1, c-IAP2, livin and XIAP. Resveratrol regulates gene transcription via activation of the stimulus-regulated protein kinases Raf and ERK and the stimulus-responsive transcription factors TCF and Egr-1.
|
163527-00-2 | 98% |
|
| BP4186 |
Withaferin A
Withaferin A(WFA) has anti-inflammatory, anti-oxidant, immune modulatory, cardioactive, antithrombotic and central nervous system effects, it could act as an anti-fibrotic compound against fibroproliferative diseases, including, but not limited to, cardiac interstitial fibrosis. WFA is a proteasomal inhibitor promotes healing after injury and exerts anabolic effect on osteoporotic bone. WFA is a potent breast cancer anti-metastatic agent and the anti-metastatic activity of WFA is, at least in part, mediated through its effects on vimentin and vimentin ser56 phosphorylation; it induces p53-dependent apoptosis by repression of HPV oncogenes and upregulation of tumor suppressor proteins in human cervical cancer cells, it can be exploited as a potent therapeutic agent for the treatment and prevention of cervical cancer without deleterious effects. Withaferin A is a withanolide that is 5,6:22,26-diepoxyergosta-2,24-diene-1,26-dione substituted by hydroxy groups at positions 4 and 27 (the 4beta,5beta,6beta,22R stereoisomer). Isolated from Physalis longifolia, it exhibits cytotoxic activity. It has a role as an antineoplastic agent and an apoptosis inducer. It is an epoxy steroid, a primary alcohol, a delta-lactone, a secondary alcohol, a 27-hydroxy steroid, an ergostanoid, an enone, a 4-hydroxy steroid and a withanolide.
|
5119-48-2 | 98% |
|
| BP1147 |
Procyanidin B2
Procyanidin B2 is a proanthocyanidin consisting of two molecules of ()-epicatechin joined by a bond between positions 4 and 8' in a beta-configuration. Procyanidin B2 can be found in Cinchona pubescens (Chinchona, in the rind, bark and cortex), in Cinnamomum verum (Ceylon cinnamon, in the rind, bark and cortex), in Crataegus monogyna (Common hawthorn, in the flower and blossom), in Uncaria guianensis (Cat's claw, in the root), in Vitis vinifera (Common grape vine, in the leaf), in Litchi chin. Procyanidin B2 has vascular protective, anti-diabetic nephropathy,anti-cancer, anti-inflammatory, and antioxidant activities. Procyanidin B2 inhibited NLRP3 inflammasome activation via suppression of AP-1 pathway, and up-regulated the expression of GSTP1 via a mechanism that involves ERK and p38 MAPK activation and Nrf2 translocation. It has anti- and pro-oxidant effects on metal-mediated DNA damage by interacting with H2O2 and metal ions.
|
29106-49-8 | 98% |
|
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