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Lipid-lowering

Dyslipidemia refers to an abnormal level of lipids (fats) in the blood, including high total cholesterol, high low-density lipoprotein (LDL) cholesterol, high triglycerides, or low high-density lipoprotein (HDL) cholesterol. These imbalances are significant risk factors for cardiovascular diseases such as atherosclerosis, heart attack, and stroke. Lipid-lowering strategies, encompassing lifestyle modifications and pharmacotherapy, aim to normalize lipid profiles and reduce associated health risks.
Catalog No Product Description CAS No. Purity Structural Formula
BP4423
Toralactone
Toralactone is an organic heterotricyclic compound that is 9,10-dihydroxy-1H-benzo[g]isochromen-1-one substituted at positions 3 and 7 by methyl and methoxy groups respectively. It has a role as a plant metabolite. It is a naphtho-alpha-pyrone, a lactone, a polyketide, an organic heterotricyclic compound, a member of phenols and an aromatic ether. It is functionally related to a nor-toralactone.
41743-74-2 98% Toralactone
BP4056
Ankaflavin
Ankaflavin is a member of cyclohexenones.
50980-32-0 98% Ankaflavin
BP1332
Soyasaponin Bb
Soyasaponin I is a triterpenoid saponin that is composed of soyasapogenol B having an alpha-L-rhamnopyranosyl-(12)-beta-D-galactopyranosyl-(12)-beta-D-glucopyranosiduronic acid moiety attached at the 3-position via a glycosidic linkage. It has a role as a sialyltransferase inhibitor. It is a pentacyclic triterpenoid, a triterpenoid saponin, a carbohydrate acid derivative and a trisaccharide derivative. It is functionally related to a soyasapogenol B. Soyasaponin Bb can suppress Eca-9706 cell growth, reverse effects on over expression of c-met, VEGF, and induce cell apoptosis through inhibiting HDAC1-NF-kappaB and activating PETEN and caspase-3 signaling pathways.
51330-27-9 98% Soyasaponin Bb
BP1331
Soyasaponin Ba
Soyasaponins(Aa, Ab, Af, Ba, Bb, and Bb') together with their derivatives may represent viable candidates for effective vaccine adjuvants due to their higher and lower or non-haemolytic effects.Soyasaponins Ab and Bb prevent scopolamine-induced memory impairment in mice without the inhibition of acetylcholinesterase.
114590-20-4 98% Soyasaponin Ba
BP1328
Soyasapogenol A
Soyasapogenol A shows estrogenic and hepatoprotective activities, it directly prevents apoptosis of hepatocytes, and secondly, inhibits the elevation of plasma TNF-α, which consequently resulted in the prevention of liver damage in the concanavalin A-induced hepatitis model. Soyasapogenol A is a pentacyclic triterpenoid that is oleanane containing a double bond between positions 12 and 13 and substituted by hydroxy groups at the 3beta, 21beta, 22beta and 24-positions. It derives from a hydride of an oleanane.
508-01-0 98% Soyasapogenol A
BP3373
Stigmasterol glucoside
Stigmasterol 3-O-beta-D-glucoside is a steroid saponin that is (3beta,22E)-stigmasta-5,22-dien-3-ol attached to a beta-D-glucopyranosyl residue at position 3 via a glycosidic linkage. It is isolated from Symplocos lancifolia. It has a role as a metabolite. It is a beta-D-glucoside, a member of phytosterols, a steroid saponin and a monosaccharide derivative. It is functionally related to a stigmasterol. It derives from a hydride of a stigmastane. Stigmasterol glucoside, a constituent of Adenanthera pavonina seed and leaf, may be a plant anticancer agent.
19716-26-8 98% Stigmasterol glucoside
BP1329
Soyasapogenol B
Soyasapogenol B is a pentacyclic triterpenoid that is oleanane containing a double bond between positions 12 and 13 and substituted by hydroxy groups at the 3beta, 22beta and 24-positions. It derives from a hydride of an oleanane. Soyasapogenol B has anti-cancer, hypocholesterolemic, anticomplementary, hepatoprotective effects, it inhibits proliferation of cultured Hep-G2.
595-15-3 98% Soyasapogenol B
BP4931 220114-28-3 98% Theasaponin E1
BP1321
Solanesol
Solanesol is a nonaprenol that is hexatriaconta-2,6,10,14,18,22,26,30,34-nonaen-1-ol substituted by 9 methyl groups at positions 3, 7, 11, 15, 19, 23, 27, 31 and 35 (the all-trans0stereoisomer). It has a role as a plant metabolite. It is a primary alcohol and a nonaprenol. Solanesol can effectively scavenge lipid radicals to block lipid peroxidation, and inhibit effects on tyrosinase; it also can protect ethanol-induced L02 cell damage, which might be attributed to the activation of HO-1 and Hsp70.
13190-97-1 98% Solanesol
BP1330
Soyasaponin Aa
Soyasaponin Aa and soyasaponin Ab dose-dependently markedly inhibit adipocyte differentiation and expression of various adipogenic marker genes, through the downregulation of the adipogenesis-related transcription factors PPARγ and C/EBPα in 3T3-L1 adipocytes.
117230-33-8 98% Soyasaponin Aa
BP4893 220114-30-7 98% Theasaponin E2
BP0926
Maslinic acid
Maslinic acid is a pentacyclic triterpenoid that is olean-12-ene substituted by hydroxy groups at positions 2 and 3 and a carboxy group at position 28 (the 2alpha,3beta stereoisomer). It is isolated from Olea europaea and Salvia canariensis and exhibits anti-inflammatory, antioxidant and antineoplastic activity. It has a role as an antioxidant, an antineoplastic agent, an anti-inflammatory agent and a plant metabolite. It is a pentacyclic triterpenoid and a dihydroxy monocarboxylic acid.
4373-41-5 98% Maslinic acid
BP4055
Monascin
Monascin is an organic heterotricyclic compound that is 3a,4,8,9a-tetrahydro-2H-furo[3,2-g][2]benzopyran-2,9(3H)-dione that is substituted at positions 3, 6, and 9a by hexanoyl, (1E)-prop-1-en-1-yl and methyl groups, respectively (the 3S,3aR,9aR diastereoisomer). One of the azaphilonoid pigments in extracts of Monascus pilosus-fermented rice (red-mould rice), it is a potent inhibitor of carcinogenesis measured against chemical- or UV-initiated, phorbol-promoted mouse skin tumours.
21516-68-7 98% Monascin
BP3441
Lovastatin
Lovastatin is an inhibitor of HMG-CoA reductase with IC50 of 3.4 nM in a cell-free assay, has a direct cellular effect independent of a cholesterol-lowering effect and delays the onset and progression of diabetic nephropathy. It has a potential application to treat PD via antioxidant effect, and it promotes fibrosis and epithelial to mesenchymal transition, by regulating the production of CCN2 in human gingival fibroblasts. Lovastatin is a fatty acid ester that is mevastatin carrying an additional methyl group on the carbobicyclic skeleton. It is used in as an anticholesteremic drug and has been found in fungal species such as Aspergillus terreus and Pleurotus ostreatus (oyster mushroom). It has a role as an antineoplastic agent, an anticholesteremic drug, a prodrug and an Aspergillus metabolite.
75330-75-5 98% Lovastatin
BP4793
Cassiaside B
Cassiaside B is a glycoside and a benzochromenone.
119170-51-3 98% Cassiaside B