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Arrhythmia

Arrhythmia, also known as cardiac dysrhythmia, is an irregular heartbeat. It occurs when the electrical impulses that coordinate heartbeats do not function properly, causing the heart to beat too fast (tachycardia), too slow (bradycardia), or with an irregular rhythm. Arrhythmias can be benign or life-threatening, depending on their type, severity, and underlying cause. Diagnosis typically involves electrocardiograms (ECGs) and other cardiac monitoring techniques.
Catalog No Product Description CAS No. Purity Structural Formula
BP0121
Aconitine
Aconitine is a diterpenoid that is 20-ethyl-3alpha,13,15alpha-trihydroxy-1alpha,6alpha,16beta-trimethoxy-4-(methoxymethyl)aconitane-8,14alpha-diol having acetate and benzoate groups at the 8- and 14-positions respectively. It is functionally related to an aconitane. Aconitine, one of the major Aconitum alkaloids, is a highly toxic compound from the Aconitum species, it appears to exert a long-lasting cholinergic action in the causation of severe arrhythmias leading to death.
302-27-2 98% Aconitine
BP5506 117457-37-1 98% Lugrandoside
BP4041
6-Prenylnaringenin
6-Prenylnaringenin is an isomer of the potent phytoestrogen, 8-prenylnaringenin. It exhibits both mixed and non-competitive inhibitory characteristics against tyrosinase, tyrosinase is the rate-limiting enzyme for the production of melanin and other pigments via the oxidation of l-tyrosine. 6-Prenylnaringenin has anti-cancer potential , dose-dependent reduction of cellular proliferation of human PC-3 prostate cancer and UO.31 renal carcinoma cells upon treatment. 6-Prenylnaringenin can inhibit 12-O-tetradecanoylphorbol 13-acetate (TPA)-induced inflammation (1μg/ear) in mice, it also exhibits inhibitory effects on skin-tumor promotion in anin vivo two-stagemouse-skin carcinogenesis test based on 7,12-dimethylbenz[a]- anthracene (DMBA) as initiator and with TPA as promoter. 6-prenylnaringenin is a trihydroxyflavanone having a structure of naringenin prenylated at C-6. It has a role as a T-type calcium channel blocker. It is a member of 4'-hydroxyflavanones, a (2S)-flavan-4-one and a trihydroxyflavanone. It is functionally related to a (S)-naringenin.
68236-13-5 98% 6-Prenylnaringenin
BP5725 1356494-03-5 98% 2'-O-Acetylthevetin A
BP3055
Adynerin
Adynerin is a cardenolide glycoside.
35109-93-4 98% Adynerin
BP0464
Dehydroevodiamine
Dehydroevodiamine has anticholinesterase activity and an anti-amnesic effect, it also may be a novel and effective ligand for improvement of beta-amyloid type amnesia. Dehydroevodiamine has antiarrhythmic, and anti-inflammatory properties, the effect of dehydroevodiamine-mediated inhibition of the expression LPS-induced iNOS and COX-2 genes is due to under the suppression of NF-kappaB activation in the transcriptional level.
67909-49-3 99% Dehydroevodiamine
BP3302
Oxypeucedanin
Oxypeucedanin is a kind of open-channel blocker of the hKv1.5 channel and it prolongs the APD, it is an excellent candidate as an antiarrhythmic drug for atrial fibrillation.Oxypeucedanin has novel anticancer effect, mediated via induction of G2-M cell cycle arrest and apoptosis in human prostate carcinoma DU145 cells. Oxypeucedanin is a furanocoumarin that is 7H-furo[3,2-g][1]benzopyran-7-one substituted by a [(2S)-3,3-dimethyloxiran-2-yl]methoxy group at position 4. It has a role as a plant metabolite. It is a furanocoumarin, a lactone and an epoxide.
737-52-0 98% Oxypeucedanin
BP3002
Corypalmine
Corypalmine (IC50=128.0±10.5 uM) can inhibit prolyl oligopeptidase. (-)-Corypalmine shows inhibition activity against spore germination of some fungi.
27313-86-6 98% Corypalmine
BP0059 60-38-8 3-Acetyl-Strophanthidin
BP1333 299-39-8 Sparteine sulfate
BP1767
Magnocurarine
Magnocurarine is a natural product from Magnolia officinalis.
6801-40-7 98% Magnocurarine
SBP01570 60008-01-7 Oblongine
BP0717 630-64-8 Helveticoside
BP0245
Benzoylhypaconine
Benzoylhypaconine is a diterpene alkaloid with formula C31H43NO9 that is isolated from several Aconitum species. It has a role as a xenobiotic, a phytotoxin, a plant metabolite, a human urinary metabolite and a rat metabolite. It is a diterpene alkaloid, a tertiary alcohol, a triol, a secondary alcohol, a bridged compound, a benzoate ester, an organic heteropolycyclic compound, a polyether and a tertiary amino compound. It derives from a hydride of an aconitane.
63238-66-4 98% Benzoylhypaconine
BP0842 32854-75-4 98% Lappaconitine
BP0337
Chasmanine
Chasmanine is a diterpene alkaloid with formula C25H41NO6 that is isolated from several Aconitum species. It has a role as an antifeedant and a plant metabolite. It is a diol, a diterpene alkaloid, a tertiary alcohol, a secondary alcohol, a bridged compound, an organic heteropolycyclic compound, a polyether and a tertiary amino compound. It derives from a hydride of an aconitane. Chasmanine, hypaconitine, and deoxyaconitine are anti-inflammatory pharmacodynamic components in Heishunpian (HSP) with positive relations with HSP efficacy. Chasmanine has insecticidal activities against larvae of Bradysia odoriphaga Yan et Zhang.
5066-78-4 98% Chasmanine
SBP02075 1422506-53-3 Rauvotetraphylline E
SBP02170 482-68-8 Sarpagine
BP2448 548-40-3 Oxyacanthine
SBP02088 1422506-49-7 Rauvotetraphylline A