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Neurological disorder

Neurological disorders encompass a broad spectrum of conditions affecting the central and peripheral nervous systems, including the brain, spinal cord, cranial nerves, peripheral nerves, nerve roots, autonomic nervous system, neuromuscular junction, and muscles. These conditions can result from genetic, infectious, environmental, or autoimmune factors, leading to diverse symptoms such as cognitive impairment, motor dysfunction, sensory disturbances, and seizures. Diagnosis often involves clinical evaluation, neuroimaging, electrophysiology, and laboratory tests.
Catalog No Product Description CAS No. Purity Structural Formula
BP1133
Praeruptorin A
Praeruptorin A exerts neuroprotective, anti-osteoclastogenic, anti-inflammatory, distinct relaxant effects, it is beneficial to facilitate nestin expression in myocarditis,and suitable in treatment of early myocarditis. Praeruptorin A can significantly up-regulate UGT1A1 expression in HepG2 cells partially via the CAR-mediated pathway. Praeruptorin A inhibited p38/Akt-c-Fos-NFATc1 signaling and PLCγ-independent Ca2+ oscillation.
73069-27-9 98% Praeruptorin A
BP0677
Glycerol trioleate
Triolein is a triglyceride formed by esterification of the three hydroxy groups of glycerol with oleic acid. Triolein is one of the two components of Lorenzo's oil. It has a role as a plant metabolite and a Caenorhabditis elegans metabolite. It is functionally related to an oleic acid.
122-32-7 98% Glycerol trioleate
SBP00113
Pinostrobin
Pinostrobin, a potent flavonoid inducer, exerts a neuroprotective effect against Aβ(25-35)-induced neurotoxicity in PC12 cells, at least in part, via inhibiting oxidative damage and calcium overload, as well as suppressing the mitochondrial pathway of cellular apoptosis. Pinostrobin has anti-inflammatory, anti-hemorrhagic and analgesic activity, it can inhibit HSV-1 replication with 50% effective concentration (EC(50)) of 22.71 ± 1.72 ug/ml. Pinostrobin is a monohydroxyflavanone that is (2S)-flavanone substituted by a hydroxy group at position 5 and a methoxy group at position 7 respectively. It has a role as an antidote and a plant metabolite. It is a monomethoxyflavanone and a monohydroxyflavanone. It is functionally related to a (2S)-flavanone.
480-37-5 98% Pinostrobin