+86-28-82633987
ISO ISO
ISO 17025 ISO 17025
usp usp
EN
CN EN

Hypercholesterolemia

Hypercholesterolemia is a metabolic disorder characterized by abnormally high levels of cholesterol in the blood. Specifically, it refers to elevated low-density lipoprotein (LDL) cholesterol, often accompanied by high total cholesterol and sometimes high triglycerides, or low high-density lipoprotein (HDL) cholesterol. This condition significantly increases the risk of atherosclerosis, coronary artery disease, stroke, and peripheral artery disease, primarily due to plaque accumulation in arterial walls. Management involves lifestyle modifications and pharmacotherapy.
Catalog No Product Description CAS No. Purity Structural Formula
BP5211
Clerosterol
Clerosterol as a precursor of cyasterone, isocyasterone and 29-norcyasterone in biosynthesis of phytoecdysteroids of Ajuga hairy roots. Clerosterol exerts its cytotoxic effect in A2058 human melanoma cells by caspases-dependent apoptosis. Clerosterol is a steroid. It derives from a hydride of a stigmastane.
2364-23-0 Clerosterol
BP1343
Stigmasterol
Stigmasterol is used as a precursor in the manufacture of synthetic progesterone, it is an antagonist of the bile acid nuclear receptor FXR, which has anti-inflammatory, thyroid inhibitory, cholesterol-lowering, antiperoxidative and hypoglycemic effects; it has indicated that stigmasterol may be useful in prevention of certain cancers, including ovarian, prostate, breast, and colon cancers. Stigmasterol inhibits the NF-kappaB pathway. Stigmasterol is a 3beta-sterol that consists of 3beta-hydroxystigmastane having double bonds at the 5,6- and 22,23-positions. It has a role as a plant metabolite. It is a stigmastane sterol, a 3beta-hydroxy-Delta(5)-steroid, a member of phytosterols and a 3beta-sterol. It derives from a hydride of a stigmastane.
83-48-7 98% Stigmasterol
SBP01859 26296-50-4 Ficaprenol 11
SBP04438 2130-17-8 Tetrahymanol
SBP00046 55722-32-2 Stigmasta-4,22-dien-3-one
BP0524
Sitogluside
Daucosterol is a steroid saponin that is sitosterol attached to a beta-D-glucopyranosyl residue at position 3 via a glycosidic linkage. It has bee isolated from Panax japonicus var. major and Breynia fruticosa. It has a role as a plant metabolite. It is a beta-D-glucoside, a steroid saponin and a monosaccharide derivative. It is functionally related to a sitosterol. It derives from a hydride of a stigmastane.
474-58-8 98% Sitogluside
SBP00828
Ganoderol A
Ganoderol A has significant anti-inflammatory activity and protection against UVA damage. it has an inhibitory effect on angiotensin converting enzyme activity and cholesterol biosynthesis.
104700-97-2 98% Ganoderol A
BP2099
22,23-Dihydroergosterol
Ergosta-5,7-dien-3beta-ol is a phytosterol consiting of ergostane having double bonds at the 5,6- and 7,8-positions as well as a 3beta-hydroxy group. It is a member of phytosterols, a 3beta-sterol and an ergostanoid. It derives from a hydride of a 5alpha-ergostane.
516-79-0 95% 22,23-Dihydroergosterol
BP0488 11024-24-1 Digitonin
BP0198
Artesunate
Artesunate is an artemisinin derivative that is the hemisuccinate ester of the lactol resulting from the reduction of the lactone carbonyl group of artemisinin. It is used, generally as the sodium salt, for the treatment of malaria. It has a role as a ferroptosis inducer, an antineoplastic agent and an antimalarial. It is a hemisuccinate, a sesquiterpenoid, a dicarboxylic acid monoester, a cyclic acetal, an artemisinin derivative and a semisynthetic derivative. Artesunate is a part of the artemisinin group of agents with an IC50 of < 5 μM for small cell lung carcinoma cell line H69. It is a potential inhibitor of STAT-3 and exhibits selective cytotoxicity of cancer cells over normal cells in vitro; A potent inhibitor of EXP1.Artesunate has anti-inflammatory activity, can prevent neuroinflammation in BV2 microglia by interfering with NF-κB and p38 MAPK signalling. Artesunate is an inhibitor of STAT-3 and export protein 1 (EXP1).
88495-63-0 98% Artesunate
BP0034
1-Octacosanol
1-Octacosanol is an ultra-long-chain primary fatty alcohol that is octacosane in which a hydrogen attached to one of the terminal carbons is replaced by a hydroxy group. It has a role as a plant metabolite. It is an ultra-long-chain primary fatty alcohol and a fatty alcohol 28:0. It derives from a hydride of an octacosane. 1-Octacosanol is reported to possess cholesterol-lowering effects, antiaggregatory properties, cytoprotective use, and ergogenic properties, it is used as a nutritional supplement. 1-Octacosanol is a straight chain aliphatic 28 carbon fatty alcohol and the main component of cholesterol lowering agent docosanol. 1-Octacosanol has various activities such as anti fatigue, anti angiogenesis, cholesterol lowering, and insecticidal.
557-61-9 95%GC 1-Octacosanol
BP4725 129095-76-7 98% Ilexoside XLVIII
BP4769
Stigmastanol
Stigmastanol is a 3-hydroxy steroid that is 5alpha-stigmastane which is substituted at the 3beta position by a hydroxy group. It has a role as an anticholesteremic drug and a plant metabolite. It is a member of phytosterols and a 3-hydroxy steroid. It derives from a hydride of a 5alpha-stigmastane.
83-45-4 98% Stigmastanol
BP2273 942950-94-9 98% Ganoderenic acid K
BP4473 469-38-5 Cycloartenol
SBP01893 848669-08-9 Stigmasta-4,25-dien-3-one
SBP01324 469-39-6 Cycloeucalenol
SBP00470 2308-85-2 Sitosteryl palmitate
BP4572 109008-26-6 98% Ilexsaponin B3
BP1701
Brassicasterol
Brassicasterol is an 3beta-sterol that is (22E)-ergosta-5,22-diene substituted by a hydroxy group at position 3beta. It is a phytosterol found in marine algae, fish, and rapeseed oil. It has a role as a biomarker, an animal metabolite, a marine metabolite, a plant metabolite, a human metabolite, an EC 1.3.1.72 (Delta(24)-sterol reductase) inhibitor, a sterol biosynthesis inhibitor and an algal metabolite. Brassicasterol may be a relevant additional biomarker in Alzheimer's disease (AD).
474-67-9 98% Brassicasterol