Trans-5-O-caffeoyl-D-quinic acid is a cinnamate ester obtained by formal condensation of the carboxy group of trans-caffeic acid with the 5-hydroxy group of quinic acid. It has a role as a plant metabolite. It is a cinnamate ester and a cyclitol carboxylic acid. It is functionally related to a trans-caffeic acid and a (-)-quinic acid. It is a conjugate acid of a trans-5-O-caffeoyl-D-quinate. Neochlorogenic acid shows antioxidant, antibacterial, antiviral, and antipyretic activities and exerts neuroprotective effects through the inhibition of pro-inflammatory pathways in activated microglia. Neochlorogenic acid is a natural polyphenolic compound found in dried fruits and other plants. Neochlorogenic acid inhibits the production of TNF - α and IL-1 β. Neochlorogenic acid inhibits the expression of iNOS and COX-2 proteins. Neochlorogenic acid also inhibits the activation of phosphorylated NF - κ B p65 and p38 MAPK.

Angelicin is a furanocoumarin. Angelicin has anti-cancer, antiviral, and anti-inflammatory activities;it regulates LPS-induced inflammation via inhibiting MAPK/NF-κB pathways. Angelicin is a powerful inducer of erythroid differentiation and -globin mRNA accumulation of human leukemia K562 cells, it is a potential therapeutic approach in hematological disorders, including -beta-thalassemia and sickle cell anemia. ngelicin is a type of furan coumarin NF - κ B and MAPK signaling inhibitor with anti-inflammatory, antiviral, and anti-tumor activities. Angelicin can inhibit the lysis and replication of gamma herpesvirus (such as MHV-68), act in the early stages of viral infection, and may inhibit RTA gene expression (IC50=28.95 μ M). Angelicin also alleviates inflammatory responses by inhibiting NF - κ B phosphorylation and nuclear translocation, as well as inhibiting p38 and JNK phosphorylation. Angelicin downregulates anti apoptotic proteins (such as Bcl-2, Bcl xL, and Mcl-1) and activates caspase-9 and caspase-3 to induce apoptosis in neuroblastoma cells.

EGCG Octaacetate is a catechin.

7-Hydroxycoumarin is a hydroxycoumarin that is coumarin substituted by a hydroxy group ay position 7. It has a role as a fluorescent probe, a plant metabolite and a food component.

In a discrete O-methyltransferase mediated reaction, 8-Hydroxybergapten is O-methylated to penicillin by cell-free extracts of Ruta cells. 8-Hydroxybergapten has excellent anti wrinkle effects.

asarone is the trans-isomer of asarone. It has a role as an anticonvulsant and a GABA modulator.

Acteoside is a glycoside that is the alpha-L-rhamnosyl-(13)-beta-D-glucoside of hydroxytyrosol in which the hydroxy group at position 4 of the glucopyranosyl moiety has undergone esterification by formal condensation with trans-caffeic acid. It has a role as an antibacterial agent, a neuroprotective agent, an anti-inflammatory agent, an antileishmanial agent and a plant metabolite. It is a glycoside, a polyphenol, a member of catechols, a cinnamate ester and a disaccharide derivative. Acteoside is a lipase inhibitor, has neuroprotective, anti-obesity,anti-inflammatory, antioxidant, anticancer, cytotoxic,antihypertensive, analgesic, and antimetastatic activities. Acteoside can promote nerve growth factor and tropomycin receptor kinase A expression, inhibit arachidonic acid release and prostaglandin E2 production induced by 0.5 microM melittin. Acteoside can protect the cells from X‑ray induced damage through enhancing the scavenging activity of ROS, decreasing the Bax/Bcl-2 ratio and downregulating the activity of procaspase-3, as well as modulating the mitogen‑activated protein kinase signaling pathways.

Bergomottin is a furanocoumarin. It has a role as a metabolite.