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Metabolic disease

Metabolic diseases are a broad category of disorders that disrupt normal metabolic processes, impacting the body's ability to convert food into energy or remove waste products. These conditions often arise from genetic mutations, enzyme deficiencies, or lifestyle factors, leading to an accumulation or deficiency of specific substances. Common examples include diabetes, hyperlipidemia, and inherited metabolic disorders, which can affect various organ systems and necessitate precise diagnostic and management strategies.
Catalog No Product Description CAS No. Purity Structural Formula
BP0135
Alismoxide
Alismoxide shows an inhibitory effect on the contraction of isolated bladder smooth muscle induced by carbachol; it demonstrates cytostatic action in HeLa cells, revealing potential use in virostatic cocktails. Alismoxide has inhibitory effects on vascular contraction induced by high concentration of KCl; it also shows an inhibitory effect on the direct passive Arthus reaction (DPAR) in rats in the type III allergic model. Alismoxide is a natural compound.
87701-68-6 98% Alismoxide
BP1163
Prunetin
Prunetin is a hydroxyisoflavone that is genistein in which the hydroxy group at position 7 is replaced by a methoxy group. It has a role as a metabolite, an EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor, an EC 1.3.1.22 [3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))] inhibitor and an anti-inflammatory agent. It is a member of 7-methoxyisoflavones and a hydroxyisoflavone. It is functionally related to a genistein. It is a conjugate acid of a prunetin-5-olate. Prunetin mediates anti-obesity/adipogenesis effects by suppressing obesity-related transcription through a feedback mechanism that regulates the expression of adiponectin, adipoR1, adipoR2, and AMPK. Prunetin and biochanin A are potent reducers of NF-κB and ERK activation, zonula occludens 1 tyrosine phosphorylation, and metalloproteinase-mediated shedding activity, which may account for the barrier-improving ability of these isoflavones.
552-59-0 98% Prunetin
BP0319
Carvacrol
Carvacrol is a phenol that is a natural monoterpene derivative of cymene. An inhibitor of bacterial growth, it is used as a food additive. Potent activator of the human ion channels transient receptor potential V3 (TRPV3) and A1 (TRPA1). It has a role as a TRPA1 channel agonist, a volatile oil component, an antimicrobial agent, an agrochemical and a flavouring agent. It is a p-menthane monoterpenoid, a member of phenols and a botanical anti-fungal agent. It derives from a hydride of a p-cymene.
499-75-2 98% Carvacrol
SBP02254
Olivil monoacetate
Prostephanaberrine is a natural product from Valeriana officinalis.
1016974-78-9 98% Olivil monoacetate
SBP02295
Deoxyelephantopin
Deoxyelephantopin has anti-inflammatory, hepatoprotective, and wound healing activities; it also has antitumor activity, by inhibiting metastatic, inducing apoptosis, modulating oxidative stress , STAT3/p53/p21 signaling, MAPK pathway, PI3k/Akt/mTOR pathway, caspase cascades, and ROS .
29307-03-7 98% Deoxyelephantopin
BP3318
Pinoresinol dimethyl ether
Pinoresinol dimethyl ether, which could be isolated from the wood of the basal tree Humbertieae, show a variety of activities as the inhibitor of cyclic AMP phosphodiesterase.
29106-36-3 98% Pinoresinol dimethyl ether
BP5291 59632-76-7 98% Anisomelic acid
BP5009
3,5,7-Trimethoxyflavone
Galangin 3,5,7-trimethyl ether is a trimethoxyflavone that is the 3,5,7-trimethyl ether derivative of galangin. It has a role as a plant metabolite. It is functionally related to a galangin.
26964-29-4 98% 3,5,7-Trimethoxyflavone
SBP00476
Viscidulin I
2-(2,6-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one is a hydroxyflavan.
92519-95-4 98% Viscidulin I
BP4638 102421-42-1 98% Yuanamide
BP5365 135545-84-5 98% 3'-hydroxy-3,4,5'-trimethoxybibenzyl
BP0137
Alisol A
Alisol A may be an autophagic inducer, it has anti-cancer activity, it presents inhibitory effects on cancer cell lines tested(HepG2, MDA-MB-231, and MCF-7 cells). Alisol A is an orally active terpenoid tetracyclic triterpenoid compound. Alisol A can be extracted from the rhizome of Alisma orientale. Alisol A activates AMPK/ACC/SREBP-1c, SIRT1, PPAR α, inhibits MMP-2/-9, and reduces the expression of inflammatory cytokines (IL-1 β, IL-6, IL-8). Alisol A has antitumor activity against breast cancer and colorectal cancer. Alisol A has anti obesity and anti atherosclerosis activities. Alisol A can be used to study hepatitis B, breast cancer, colorectal cancer, atherosclerosis and obesity.
19885-10-0 98% Alisol A
BP0506
Diosmetin
Diosmetin has anti-osteoporosis, cytoprotective, antibacterial, anti-pigmentation, anti-inflammatory and antioxidant properties, it induces osteoblastic differentiation through the PKCδ-Rac1-MEK3/6-p38 and PKCδ-Rac1-MEK1/2- ERK1/2-Runx2 pathways.Diosmetin has intracellular antioxidant detoxifying effect, the mechanism is associated with both nonenzymatic and enzymatic defense systems.Diosmetin and luteolin exert synergistic cytostatic effects in human hepatoma HepG2 cells via CYP1A-catalyzed metabolism, activation of JNK and ERK and P53/P21 up-regulation. Diosmetin is a monomethoxyflavone that is the 4'-methyl ether derivative of luteolin. It is a natural product isolated from citrus fruits which exhibits a range of pharmacological activities. It has a role as a tropomyosin-related kinase B receptor agonist, an antioxidant, an antineoplastic agent, a vasodilator agent, an angiogenesis inhibitor, a bone density conservation agent, an anti-inflammatory agent, an apoptosis inducer, a plant metabolite and a cardioprotective agent.
520-34-3 98% Diosmetin
BP0041
20(R)-Ginsenoside Rh1
20(R)-Ginsenoside Rh1 is a triterpenoid saponin.
80952-71-2 98% 20(R)-Ginsenoside Rh1
BP5005 107347-56-8 98% Tenacissoside E
SBP00301 135541-40-1 Cudraxanthone L
BP4979
Dicoumarol
Dicoumarol is a hydroxycoumarin that is methane in which two hydrogens have each been substituted by a 4-hydroxycoumarin-3-yl group. Related to warfarin, it has been used as an anticoagulant. It has a role as an anticoagulant, an EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor, a vitamin K antagonist and a Hsp90 inhibitor.
66-76-2 98% Dicoumarol
SBP00242
Ilicic acid
Ilicic acid is a eudesmane sesquiterpenoid.
4586-68-9 98% Ilicic acid
SBP01399 104975-02-2 3-Acetoxy-4,7(11)-cadinadien-8-one
SBP03107 262272-76-4 3α-Acetoxy-20-oxo-29-norlupane-23,28-dioic acid