Acacetin is a monomethoxyflavone that is the 4'-methyl ether derivative of apigenin. It has a role as an anticonvulsant and a plant metabolite. It is a monomethoxyflavone and a dihydroxyflavone. It is functionally related to an apigenin. It is a conjugate acid of a 5-hydroxy-2-(4-methoxyphenyl)-4-oxo-4H-chromen-7-olate. Acacetin is an atrium-selective agent that prolongs the atrial effective refractory period without prolonging the corrected QT interval and effectively prevents atrial fibrillation (AF) in anesthetized dogs after intraduodenal administration. Acacetin has anti-cancer, anti-mutagenic, spasmolytic and antinociceptive, anti-inflammatory and anti-peroxidative effects. Acacetin is an orally effective flavonoid derived from Dendranthema morifolium. Acacetin stops in the ATP binding pocket of PI3K γ. Acacetin causes cancer cell cycle arrest and induces apoptosis and autophagy. Acacia extract has effective anti-cancer and anti-inflammatory activities, and has the potential for research on pain related diseases.

Notoginsenoside Ft1 is a novel stimulator of angiogenesis, it stimulates angiogenesis via HIF-1α-mediated VEGF expression, with PI3K/AKT and Raf/MEK/ERK signaling cascades concurrently participating in the process; it has the potential therapeutic effect on human neuroblastoma, it can arrest the proliferation and elicited the apoptosis of SH-SY5Y cells possibly via p38 MAPK and ERK1/2 pathways.Notoginsenoside Ft1 activates both glucocorticoid and estrogen receptors to induce endothelium-dependent, nitric oxide-mediated relaxations in rat mesenteric arteries. Notoginsenoside Ft1 also provides a great potential application of it in clinics for patients with diabetic foot ulcers, it may accelerate diabetic wound healing by orchestrating multiple processes, including promoting fibroblast proliferation, enhancing angiogenesis, and attenuating inflammatory response.

Aristololactam, the main metabolite of aristolochic acid , it can lead to renal damage, the cytotoxic potency of Aristololactam is higher than that of aristolochic acid and that the cytotoxic effects of these molecules are mediated through the induction of apoptosis in a caspase 3-dependent pathway.

Petunidin chloride is an anthocyanidin chloride that has petunidin as the cationic component. It has a role as a metabolite. Petunidin chloride has antioxidant, and anti-carcinogenesis activities.

1,4-Di-O-caffeoylquinic acid is a quinic acid.

Alpinetin is an ether and a member of flavonoids. Alpinetin has antibacterial, anti-inflammatory, and anti-cancer activities; it inhibits proliferation ,regulates of the Bcl-2 family and XIAP expression, releases of cytochrome c and activates caspases. Alpinein is a flavonoid compound isolated from cardamom, which has anti-tumor, anti-inflammatory, liver protective, cardiovascular protective, lung protective, antibacterial, antiviral, and neuroprotective properties. Alpinetin can inhibit inflammation caused by lipopolysaccharide (LPS), activate PPAR - γ, activate Nrf2, and inhibit the expression of TLR4 to protect against LPS induced kidney injury.

10-Gingerol is a monomethoxybenzene, a member of phenols and a beta-hydroxy ketone. 10-Gingerol is an AMPK agonist found in fresh ginger rhizome oil resin, with anti-inflammatory, antioxidant, and anti proliferative activities. 10-Gingerol inhibits neointimal hyperplasia and suppresses the proliferation of vascular smooth muscle cells. The IC50 value of 10-Gingerol for DPPH radical scavenging activity is 10.47 μ M, for superoxide radical scavenging activity is 1.68 μ M, and for hydroxyl radical scavenging activity is 1.35 μ M. 10 Gingerol has an inhibitory effect on the proliferation of MDA-MB-231 tumor cell line, with an IC50 value of 12.1 μ M. 10-Gingerol inhibits proliferation, migration, invasion, and induces apoptosis by targeting the PI3K/Akt signaling pathway in MDA-MB-231/IR cells. 10-Gingerol is expected to be used in research on ulcerative colitis. 10-Gingerol has anti-cancer, anti-neuroinflammatory, and anti-bacterial effects, it effectively inhibits the growth of the oral pathogens, and inhibits exogenous ghrelin deacylation.10-Gingerol induces [Ca2+]i rise by causing Ca2+ release from the endoplasmic reticulum and Ca2+ influx from non-L-type Ca2+ channels in SW480 cancer cells.10-Gingerol-induced apoptosis was accompanied by phosphorylation of the mitogen-activated protein kinase (MAPKs) family, c-Jun N-terminal kinase (JNK), p38 MAPK (p38), and extracellular signal-regulated kinase (ERK).

Baohuoside aglycone possesses cardioprotective effect in prevention of ischemia/ reperfusion injury and reduce the myocardial infraction, the mechnism is due to the reduction of the injury of free radicals.

Muscone, a flavouring ingredient, is an organic compound that is the primary contributor to the odor of musk. Muscone has neuroprotective, anti-fibrotic, anti-inflammatory and anti-apoptotic effects, it can protect PC12 cells against glutamate -induced apoptosis by attenuating ROS generation and Ca2+ influx, via NR1 and CaMKII-depended ASK-1/JNK/p38 signaling pathways. Muscone can permeate the BBB model, and it is associated with the inhibition of P-gp and MMP-9 expression, is the important mechanisms for treating cerebral vascular diseases.

Tectochrysin is a monohydroxyflavone that is flavone substituted by a hydroxy group at position 4 and a methoxy group at position 7 respectively. It has a role as an antineoplastic agent, an antidiarrhoeal drug and a plant metabolite. It is a monomethoxyflavone and a monohydroxyflavone. It is functionally related to a flavone.

Quinidine is a cinchona alkaloid consisting of cinchonine with the hydrogen at the 6-position of the quinoline ring substituted by methoxy. It has a role as an alpha-adrenergic antagonist, an antimalarial, an anti-arrhythmia drug, a sodium channel blocker, a muscarinic antagonist, a P450 inhibitor, a potassium channel blocker, an EC 3.6.3.44 (xenobiotic-transporting ATPase) inhibitor, an EC 1.14.13.181 (13-deoxydaunorubicin hydroxylase) inhibitor and a drug allergen. Quinidine, a useful antiarrhythmic compound, is usually contaminated with dihydroquinidine, a compound that itself shows potent antiarrhythmic activity.

The role of our hybrid molecules, an analogue of Salvianolic acid F, in compelling the glioma cells towards apoptosis by specifically perturbing the concentration of glutathione along with caspase 6.

Curdione has anti-inflammatory, cancer chemopreventive activities, significant anti-platelet aggregation and antithrombotic activities , the inhibitory mechanism of curdione on platelet aggregation may increase cAMP levels and subsequently inhibit intracellular Ca2+ mobilization. plays an important role in the CYP3A4 inhibitory activity of C. aromatica.