| Catalog No | Product Description | CAS No. | Purity | Structural Formula |
|---|---|---|---|---|
| BP0012 |
10-Deacetyltaxol
10-Deacetyltaxolis a taxane diterpenoid.
10 Deactyltaxol is a paclitaxel derivative isolated from Taxus chinensis. 10 Deactyltaxol can promote the polymerization of microtubules and inhibit microtubule depolymerization induced by cold or calcium ions in vitro. 10 Deathtyltaxol exhibits cytotoxicity towards human glioblastoma and neuroblastoma cells.
|
78432-77-6 | 98% |
|
| BP0011 |
10-deacetylbaccatin III
10-deacetylbaccatin III is a secondary alpha-hydroxy ketone and a tetracyclic diterpenoid. It is functionally related to a baccatin III.
10-Deacetylbacccatin III is an antineoplastic agent and an anti-cancer intermediate, it can selectively inhibit the growth of L. donovani intracellular amastigotes within J774 murine macrophages in vitro at nanomolar concentrations with an IC50 value of 70 nM.
The 10-Deacetylbaccatin III-treated promastigotes were slightly arrested in the G2/M phase whereas taxol-treated cells were blocked in the G2/M phase.
|
32981-86-5 | 98% |
|
| BP0672 |
Gitogenin
Gitogenin is a novel selective inhibitor of UGT1A4, it is also an inhibitor of enzyme α-glucosidase with IC50 values of 37.2±0.18 uM.Gitogenin shows moderate stimulation of release activity on growth hormone from rat pituitary cells.
|
511-96-6 | 98% |
|
| BP0225 |
Baccatin III
Baccatin III, which is the precursor for the semisynthesis of paclitaxel,exerts anti-tumor immunomodulatory activity in very low doses (0.05-0.5mg/kg),it reduces tumor progression by inhibiting the accumulation and suppressive function of MDSCs. Baccatin III also exerts immunomodulatory activities in vivo as well as in vitro on the MHC-restricted antigen presentation. Baccatin III is a tetracyclic diterpenoid isolated from plant species of the genus Taxus. It has a role as a plant metabolite. It is a benzoate ester, an acetate ester and a tetracyclic diterpenoid. It derives from a hydride of a taxane.
|
27548-93-2 | 98% |
|
| BP0080 |
Euphorbia Factor L3
Euphorbia Factor L3 is a diterpenoid.
|
218916-52-0 | 98% |
|
| BP0023 | 142203-65-4 | 98% |
|
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