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Cerebral Ischemia

Cerebral ischemia is a condition characterized by insufficient blood flow to the brain, leading to inadequate oxygen and nutrient supply. This deprivation can result in neuronal damage or death, manifesting as a range of neurological deficits. It can be focal, affecting a specific brain region (e.g., ischemic stroke), or global, impacting the entire brain (e.g., cardiac arrest). Prompt diagnosis and intervention are crucial to minimize irreversible brain injury and improve patient outcomes.
Catalog No Product Description CAS No. Purity Structural Formula
BP0033
Inulicin
Inulicin is a terpene lactone.
33627-41-7 98% Inulicin
BP2299 28251-63-0 98% 2,3,4,6-tetraacetate Salidroside
BP0089
5-O-methylvisammioside
5-O-Methylvisammioside is a naturally occuring product isolated from Saposhnikovia Divaricata and has analgesic, antipyretic, anti-inflammatory and anti-platelet aggregation effects.
84272-85-5 98% 5-O-methylvisammioside
BP3923 54483-84-0 3α-dihydrocadambine
BP2187
Ginkgotoxin
Ginkgotoxin is a member of pyridines.
1464-33-1 98% Ginkgotoxin
BP1772
Scutellarin methyl ester
Scutellarin has many pharmacological effects, such as antioxidant, antitumor, antiviral, neuroprotection and antiinflammatory activities. It down-regulates the STAT3/Girdin/Akt signaling in HCC cells, and inhibits RANKL-mediated MAPK and NF-κB signaling pathway in osteoclasts. Scutellarin methyl ester is a glucosiduronic acid and a member of flavonoids.
119262-68-9 98% Scutellarin methyl ester
BP0247
Benzoyloxypaeoniflorin
Beta-benzoyloxypaeoniflorin is a monoterpene glycoside with formula C30H32O13, isolated from several species of Paeoniae. It has a role as a platelet aggregation inhibitor, an EC 1.14.18.1 (tyrosinase) inhibitor and a plant metabolite. It is a beta-D-glucoside, a bridged compound, a lactol, an O-acyl carbohydrate, a cyclic acetal, a monoterpene glycoside and a 4-hydroxybenzoate ester.
72896-40-3 98% Benzoyloxypaeoniflorin
BP1296
Sesamin
Sesamin has antifibrotic, cholesterol-lowering, anti-cancer, antioxidative, neuroprotective, anti-atherosclerosis, anti-inflammatory properties, it also might be beneficial in the prevention of hypertension and stroke. Sesamin attenuates intercellular cell adhesion molecule-1 expression in vitro in TNF-α-treated human aortic endothelial cells and in vivo in apolipoprotein-E-deficient mice.Sesamin also can protect β-cells from damage caused by AGEs through suppressing NADPH oxidase-mediated oxidative stress. (+)-sesamin is a lignan that consists of tetrahydro-1H,3H-furo[3,4-c]furan substituted by 1,3-benzodioxole groups at positions 1 and 4 (the 1S,3aR,4S,6aR stereoisomer). Isolated from Cinnamomum camphora, it exhibits cytotoxic activity. It has a role as an antineoplastic agent, a neuroprotective agent and a plant metabolite. It is a lignan, a member of benzodioxoles and a furofuran.
607-80-7 98% Sesamin
BP4917
Borneol 7-O-[β-D-apiofuranosyl-(1→6)]-β-D-glucopyranoside
(+)-Borneol is a bicyclic monoterpene used for analgesia and anaesthesia in traditional Chinese and Japanese medicine, it and its enantiomer (-)-borneol have a highly efficacious positive modulating action at GABA(A) receptors at human recombinant alpha1beta2gamma2L GABA(A) receptors. Borneol specifically inhibits the nicotinic acetylcholine receptor (nAChR)-mediated effects in a noncompetitive way, can depress P-glycoprotein function by a NF-κB signaling mediated mechanism in a blood brain barrier in vitro model. Borneol has neuroprotection through the inhibition of IκBα-NF-κB and translocation signaling pathway, it also has an anti-cerebral ischemia effects. It can suppresse inflammatory responses in LPS-induced acute lung injury through inhibition of the NF-κB and MAPKs signaling pathways.
88700-35-0 98% Borneol 7-O-[β-D-apiofuranosyl-(1→6)]-β-D-glucopyranoside
BPI008 50428-14-3 98% Nifedipine impurity B
BP0976 1422186-34-2 N,N'-dimethyldaurisoline iodide
BP2276 660397-15-9 90% Heterophyllin J
BP0049
(±)-Borneol
(±)-Borneol is a bornane monoterpenoid that is 1,7,7-trimethylbicyclo[2.2.1]heptane substituted by a hydroxy group at position 2. It has a role as a metabolite and a volatile oil component.(±)-Borneol is a bornane monoterpenoid that is 1,7,7-trimethylbicyclo[2.2.1]heptane substituted by a hydroxy group at position 2. It has a role as a metabolite and a volatile oil component. (±)-Borneol is a bicyclic monoterpene used for analgesia and anaesthesia in traditional Chinese and Japanese medicine, it and its enantiomer (±)-Borneol have a highly efficacious positive modulating action at GABA(A) receptors at human recombinant alpha1beta2gamma2L GABA(A) receptors. Borneol specifically inhibits the nicotinic acetylcholine receptor (nAChR)-mediated effects in a noncompetitive way, can depress P-glycoprotein function by a NF-κB signaling mediated mechanism in a blood brain barrier in vitro model. Borneol has neuroprotection through the inhibition of IκBα-NF-κB and translocation signaling pathway, it also has an anti-cerebral ischemia effects. It can suppresse inflammatory responses in LPS-induced acute lung injury through inhibition of the NF-κB and MAPKs signaling pathways.
507-70-0 98% (±)-Borneol
BP1438
Vincamine
Vincamine is a plant alkaloid used clinically as a peripheral vasodilator that increases cerebral blood flow and oxygen and glucose utilization by neural tissue to combat the effect of aging. Vincamine has contractile and relaxant actions on the guinea pig trachealis, may be due to the generation of prostaglandins and to changes in the membrane Ca2+ fluxes and/or the intracellular Ca2+ distribution. Vincamine alleviates Amyloid-β 25-35 peptides-induced cytotoxicity in PC12 cells. Vincamine is a methyl ester, a vinca alkaloid, an organic heteropentacyclic compound, an alkaloid ester and a hemiaminal. It has a role as a metabolite, a vasodilator agent and an antihypertensive agent. It is functionally related to an eburnamenine.
1617-90-9 98% Vincamine
BP2261 1945997-27-2 98% Magnoloside F
BP0004
1,3,6-Trigalloylglucose
Gallotannin is a class of hydrolysable tannins obtained by condensation of the carboxy group of gallic acid (and its polymeric derivatives) with the hydroxy groups of a monosaccharide (most commonly glucose). It is functionally related to a gallic acid.
18483-17-5 98% 1,3,6-Trigalloylglucose
BP3264
Caffeoylputrescine
N-(4-Aminobutyl)-3-(3,4-dihydroxyphenyl)prop-2-enamide is a hydroxycinnamic acid.
29554-26-5 98% Caffeoylputrescine