Vindoline is a chemical precursor to vinblastine and exhibits antimitotic activity by inhibiting microtubule assembly, it also has anti-ulcer activity. Vindoline can enhance the glucose-stimulated insulin secretion (GSIS) in MIN6 cells with the EC50 value of 50.2uM; it has relaxant effects in isolated rat renal arteries, it can dilate renal arteries in vitro through one or more pathways including inhibition of calcium entry,TEA+-sensitive potassium channel or protein kinase pathways in vascular smooth muscle cells. Vindoline is a methyl ester, a tertiary alcohol, a vinca alkaloid, an organic heteropentacyclic compound, an alkaloid ester, an acetate ester and a tertiary amino compound. It is a conjugate base of a vindolinium(1+).

Vincristine-induced nociceptive painful sensation, may be due to its potential of antioxidative, neuroprotective and calcium channel inhibitory action.Vincristine can treat MM, ERK1/2, Akt, and NF-κB inhibitors are potentially useful as anti-MDR agents for the treatment of Vincristine-resistant MM. An inherited polymorphism in the promoter region of CEP72 was associated with increased risk and severity of Vincristine-related peripheral neuropathy. Vincristine is a vinca alkaloid with formula C46H56N4O10 found in the Madagascar periwinkle, Catharanthus roseus. It is used (commonly as the corresponding sulfate salt)as a chemotherapy drug for the treatment of leukaemia, lymphoma, myeloma, breast cancer and head and neck cancer. It has a role as a drug, an antineoplastic agent, a tubulin modulator, a microtubule-destabilising agent and a plant metabolite.

Vincristine sulfate is an antitumor vinca alkaloid which inhibits microtubule formation in mitotic spindle, resulting in an arrest of dividing cells at the metaphase stage. It binds to microtubule with a Ki of 85 nM. Vincristine Sulfate can cause developmental toxicity according to state or federal government labeling requirements.

Vinblastine Sulfate has anticancer activity, using FA-BSANPs as a drug carrier system could be effective in targeting Vinblastine Sulfate-sensitive tumors in the future. Vinblastine Sulfate could offer protection to the normal tissues against gamma-radiation-induced DNA strand breaks. The changes induced on the rabbit OM by Vinblastine sulphate are transient and that regenerative recovery leads to the restoration of the normal structure of the mucosa. Vinblastine Sulfate can cause developmental toxicity according to state or federal government labeling requirements.

Vinorelbine Tartrate is an antitumor drug.

Ganoderic acid T-Q and TR are two inhibitors of H5N1 and H1N1 NAs.