| Catalog No | Product Description | CAS No. | Purity | Structural Formula |
|---|---|---|---|---|
| BP0098 |
7-Epitaxol
7-Epitaxol is the major derivative of taxol found in cells and taxol (paclitaxel) is a well-known natural-source cancer drug.
|
105454-04-4 | 98% |
|
| BP1443 |
Vindoline
Vindoline is a chemical precursor to vinblastine and exhibits antimitotic activity by inhibiting microtubule assembly, it also has anti-ulcer activity. Vindoline can enhance the glucose-stimulated insulin secretion (GSIS) in MIN6 cells with the EC50 value of 50.2uM; it has relaxant effects in isolated rat renal arteries, it can dilate renal arteries in vitro through one or more pathways including inhibition of calcium entry,TEA+-sensitive potassium channel or protein kinase pathways in vascular smooth muscle cells. Vindoline is a methyl ester, a tertiary alcohol, a vinca alkaloid, an organic heteropentacyclic compound, an alkaloid ester, an acetate ester and a tertiary amino compound. It is a conjugate base of a vindolinium(1+).
|
2182-14-1 | 98% |
|
| BP4098 |
Combretastatin A4
Combretastatin A4 is a stilbenoid.
|
117048-59-6 | 98% |
|
| BP4068 |
Dehydroandrographolide succinate
Dehydroandrographolide succinate can alleviate oxidative stress in LPS-induced acute lung injury possibly by inactivating iNOS. It combined with ribavirin treatedchildren with hand-foodand mouth disease,the duration of fever was shorter,rashes on hands and feet more quickyly.
|
786593-06-4 | 98% |
|
| SBP00202 | 705973-69-9 |
|
||
| BP1611 |
Corydine
Corydine is the adrenolytic and weak cholinergic agent, it shows antimicrobial, and antineoplastic activities. Corydine shows irritant and respiratory stimulant and CNS depressant activities. Injected intravenously in rabbits corydine produced an initial fall in blood pressure followed by a return to normal or above normal.
|
476-69-7 | 98% |
|
| SBP00247 | 97931-41-4 |
|
||
| SBP00214 | 38072-88-7 |
|
||
| SBP00223 | 18457-44-8 |
|
||
| BP3378 |
Taccalonolide A
Taccalonolide A is the first microtubule stabilizing agent to be discovered from a plant since identification of the mechanism of action of paclitaxel and it is the first natural product steroid identified to have these cellular effects.
|
108885-68-3 | 98% |
|
| SBP03207 | 464-85-7 |
|
||
| BP0304 | 18830-99-4 |
|
||
| SBP02936 | 107633-69-2 |
|
||
| BP1439 |
Vincristine
Vincristine-induced nociceptive painful sensation, may be due to its potential of antioxidative, neuroprotective and calcium channel inhibitory action.Vincristine can treat MM, ERK1/2, Akt, and NF-κB inhibitors are potentially useful as anti-MDR agents for the treatment of Vincristine-resistant MM. An inherited polymorphism in the promoter region of CEP72 was associated with increased risk and severity of Vincristine-related peripheral neuropathy. Vincristine is a vinca alkaloid with formula C46H56N4O10 found in the Madagascar periwinkle, Catharanthus roseus. It is used (commonly as the corresponding sulfate salt)as a chemotherapy drug for the treatment of leukaemia, lymphoma, myeloma, breast cancer and head and neck cancer. It has a role as a drug, an antineoplastic agent, a tubulin modulator, a microtubule-destabilising agent and a plant metabolite.
|
57-22-7 | 98% |
|
| BP0075 |
4'-Demethylepipodophyllotoxin
4'-demethylepipodophyllotoxin is an organic heterotetracyclic compound that is the 9- epimer of 4'-demethylpodophyllotoxin. It has a role as an antineoplastic agent. It is a member of phenols, an organic heterotetracyclic compound and a furonaphthodioxole.
|
6559-91-7 | 98% |
|
| BP0012 |
10-Deacetyltaxol
10-Deacetyltaxolis a taxane diterpenoid.
10 Deactyltaxol is a paclitaxel derivative isolated from Taxus chinensis. 10 Deactyltaxol can promote the polymerization of microtubules and inhibit microtubule depolymerization induced by cold or calcium ions in vitro. 10 Deathtyltaxol exhibits cytotoxicity towards human glioblastoma and neuroblastoma cells.
|
78432-77-6 | 98% |
|
| SBP00261 | 82508-34-7 |
|
||
| BP4823 | 1617-84-1 | 98% |
|
|
| BP2006 |
Laetanine
Laetanine is an isoquinoline alkaloid.
|
72361-67-2 | 97% |
|
| BP0011 |
10-deacetylbaccatin III
10-deacetylbaccatin III is a secondary alpha-hydroxy ketone and a tetracyclic diterpenoid. It is functionally related to a baccatin III.
10-Deacetylbacccatin III is an antineoplastic agent and an anti-cancer intermediate, it can selectively inhibit the growth of L. donovani intracellular amastigotes within J774 murine macrophages in vitro at nanomolar concentrations with an IC50 value of 70 nM.
The 10-Deacetylbaccatin III-treated promastigotes were slightly arrested in the G2/M phase whereas taxol-treated cells were blocked in the G2/M phase.
|
32981-86-5 | 98% |
|
Shenshuai
Wenjing
Hedandan