All-cis-5,8,11,14,17-icosapentaenoic acid is an icosapentaenoic acid having five cis-double bonds at positions 5, 8, 11, 14 and 17. It has a role as a micronutrient, an antidepressant, an antineoplastic agent, an anticholesteremic drug, a nutraceutical, a mouse metabolite, a fungal metabolite and a Daphnia galeata metabolite. It is an omega-3 fatty acid and an icosapentaenoic acid. It is a conjugate acid of an all-cis-5,8,11,14,17-icosapentaenoate.

Gingerol is a beta-hydroxy ketone that is 5-hydroxydecan-3-one substituted by a 4-hydroxy-3-methoxyphenyl moiety at position 1; believed to inhibit adipogenesis. It is a constituent of fresh ginger. It has a role as an antineoplastic agent and a plant metabolite. It is a member of guaiacols and a beta-hydroxy ketone. 6-Gingerol possesses anti-adipogenic, anti-tumorigenic, anti-invasive, antioxidant, anti-inflammatory, and pro-apoptotic activities, it stimulates apoptosis through upregulation of NAG-1 and G1 cell cycle arrest through downregulation of cyclin D1, multiple mechanisms appear to be involved in 6-gingerol action, including protein degradation as well as β-catenin, PKCε, and GSK-3β pathways. 6-Gingerol can effectively suppress adipogenesis and that it exerts its role mainly through the significant down-regulation of PPARγ and C/EBPα and subsequently inhibits FAS and aP2 expression, also inhibit differentiation in 3T3-L1 cells by attenuating the Akt/GSK3β pathway.

Arctiin is a glycoside and a lignan. Arctiin, a plant lignan that can be extracted from the Arctium lappa (burdock) seeds, is a possible environmental endocrine disruptor compounds and have been shown to influence sex hormone metabolism as well as protein synthesis, steroid biosynthesis. Arctiin has been reported to have preventing obesity, antibacterial, antiviral, anti-inflammatory, and anti-oxidant effects in vitro. Arctiin inhibits adipogenesis in 3T3-L1 adipocytes through the inhibition of PPARγ and C/EBPα and the activation of AMPK signaling pathways. Arctiin also has a protective effect on ROS-induced cell dysfunction in HHDPCs and may therefore be useful for alopecia prevention and treatment strategies. Arctiin is an orally active NF - κ B inhibitor. Arctiin inhibits the expression of cyclin D1 protein in human tumor cells. Arctiin can also reduce levels of malondialdehyde and pro-inflammatory cytokines. Arctiin can be used for the study of glomerulonephritis.