+86-28-82633987
ISO ISO
ISO 17025 ISO 17025
usp usp
EN
CN EN

Schistosoma Proteases

Catalog No Product Description CAS No. Purity Structural Formula
BP1395
Timosaponin AIII
Timosaponin A-III is a natural product found in Anemarrhena asphodeloides. It has a role as a metabolite.
41059-79-4 98% Timosaponin AIII
BP0397
Corylifol A
Corylifol A is a naturally occurring potent inhibitor of hCE2 and UDP-glucuronosyltransferase 1A1 (UGT1A1); it could be the potential uncouplers of neuronal nitric oxide synthase-postsynaptic density protein-95. Corylifol A displays cytotoxic activity against HepG2 and Hep3B hepatocellular carcinoma cell lines, with IC50 values of 4.6 and 13.5 ug/ml, respectively. Corylifol A has antiinflammatory activity, it shows an inhibitory effect on IL-6-induced STAT3 promoter activity in Hep3B cells with IC50 values of 0.81 ± 0.15 uΜ, it also inhibits STAT3 phosphorylation induced by IL-6 in Hep3B cells.
775351-88-7 98% Corylifol A
BP0527
Eleutheroside E
Eleutheroside E is a glycoside and a lignan.
39432-56-9 98% Eleutheroside E
BP5286 2366153-27-5 98% 1,6,8-Trihydroxy-2,7-dimethoxy-3-methylanthraquinone
BP0307
Campesterol
Campesterol is a plant sterol with cholesterol lowering and anticarcinogenic effects, it and other plant sterols often decrease LDL cholesterol levels overall. Campesterol has anti-inflammatory effect, it inhibits several pro-inflammatory and matrix degradation mediators typically involved in osteoarthritis- induced cartilage degradation, also sometimes used to treat some specific prostate conditions. Campesterol is a 3beta-hydroxy-Delta(5)-steroid, a C28-steroid, a member of phytosterols and a 3beta-sterol. It has a role as a mouse metabolite. It derives from a hydride of a campestane.
474-62-4 98% Campesterol
BP0705
Hecogenin
Hecogenin, a steroid saponin isolated from Agave sisalana, is a potent and highly selective inhibitor of UGT1A4 with an IC50 value of 1.5 μM. Hecogenin has anti-cancer, antiproliferative,antioxidant and anti-inflammatory effects, it can protect gastro by K⁺(ATP) channels opening and the COX-2/PG pathway. Hecogenin has inhibition of human rheumatoid arthritis synovial cell survival, the effect is associated with increased apoptosis, p38 mitogen-activated protein kinase activity and upregulation of cyclooxygenase-2.
467-55-0 98% Hecogenin
BP0431 2611-67-8 98% Cyanidin-3,5-di-O-glucoside chloride
BP4006
Licoflavone A
Licoflavone A is a member of flavones.
61153-77-3 98% Licoflavone A
BP5346
Artesunate Peroxy Hemiacetal
Artesunate is a part of the artemisinin group of agents with an IC50 of < 5 μM for small cell lung carcinoma cell line H69. It is a potential inhibitor of STAT-3 and exhibits selective cytotoxicity of cancer cells over normal cells in vitro; A potent inhibitor of EXP1.Artesunate has anti-inflammatory activity, can prevent neuroinflammation in BV2 microglia by interfering with NF-κB and p38 MAPK signalling.
958447-25-1 98% Artesunate Peroxy Hemiacetal
BP1323
Solasonine
Solasonine displays leishmanicidal activity against promastigote forms of L. amazonensis. Solasonine is a steroid, an azaspiro compound and an oxaspiro compound.
19121-58-5 98% Solasonine
BP0899
Luteoloside
Luteolin 7-O-beta-D-glucoside is a glycosyloxyflavone that is luteolin substituted by a beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage. It has a role as an antioxidant and a plant metabolite. It is a beta-D-glucoside, a trihydroxyflavone, a glycosyloxyflavone and a monosaccharide derivative. It is functionally related to a luteolin. It is a conjugate acid of a luteolin 7-O-beta-D-glucoside(1-).
5373-11-5 98% Luteoloside
BP0105
8-Acetylharpagide
8-O-Acetylharpagide is a glycoside and an iridoid monoterpenoid.
6926-14-3 98% 8-Acetylharpagide
BP1293
Sennoside B
Sennoside B is a member of the class of sennosides that is (9R,9'S)-9,9',10,10'-tetrahydro-9,9'-bianthracene-2,2'-dicarboxylic acid which is substituted by hydroxy groups at positions 4 and 4', by beta-D-glucopyranosyloxy groups at positions 5 and 5', and by oxo groups at positions 10 and 10'. It is an oxo dicarboxylic acid and a member of sennosides. Sennoside B, a major purgative component, has a potential utility in the treatment of proliferative diseases, through inhibiting PDGF-stimulated cell proliferation by binding to PDGF-BB and its receptor and by down-regulating the PDGFR-beta signaling pathway. It and sennoside A also possess significant gastroprotective activities .
128-57-4 98% Sennoside B
BP1669
Fuscaxanthone C
1-Hydroxy-3,6,7-trimethoxy-2,8-diprenylxanthone is a member of xanthones. Fuscaxanthone C is a natural product from Garcinia mangostana.
15404-76-9 98% Fuscaxanthone C
BP0027
15,16-Dihydrotanshinone I
15,16-Dihydrotanshinone I is an abietane diterpenoid. It has a role as an anticoronaviral agent.
87205-99-0 98% 15,16-Dihydrotanshinone I
BP0687
Gossypol
Gossypol is an effective natural antimicrobial agent against a wide range of potential fungal pathogens of cotton.Gossypol shows a significant increase in accumulation of acidic vesicular organelle, is a promising drug that induces autophagic cell death in radioresistant malignant glioma.Gossypol binds to Bcl-xL protein and Bcl-2 protein with Kis of 0.5-0.6 μM and 0.2-0.3 mM, respectively. Gossypol is an aldehyde, a hydroxynaphthalene, a polyphenol and a hexol. It has a role as an antispermatogenic agent, an anti-inflammatory agent and a plant metabolite.
303-45-7 98% Gossypol
BP1473
Ginsenoside RK2
Ginsenoside Rk1 has anti-tumor, and anti-platelet aggregation activities. Ginsenoside Rk1 can strongly inhibit permeability induced by VEGF, advance glycation end-product, thrombin, or histamine in human retinal endothelial cells, it reduces the vessel leakiness of retina in a diabetic mouse model; this anti-permeability activity of Rk1 is correlated with enhanced stability and positioning of tight junction proteins at the boundary between cells; Rk1 induces phosphorylation of myosin light chain and cortactin, which are critical regulators for the formation of the cortical actin ring structure and endothelial barrier.
364779-14-6 98% Ginsenoside RK2
BP5359 3649-76-1 98% Ebelin lactone
BP5211
Clerosterol
Clerosterol as a precursor of cyasterone, isocyasterone and 29-norcyasterone in biosynthesis of phytoecdysteroids of Ajuga hairy roots. Clerosterol exerts its cytotoxic effect in A2058 human melanoma cells by caspases-dependent apoptosis. Clerosterol is a steroid. It derives from a hydride of a stigmastane.
2364-23-0 Clerosterol
BP0401
Costunolide
Costunolide has antipyretic, anti-inflammatory, anti-oxidant, anti-carcinogenic and anti-fungal activities, it possesses normo-glycemic and hypolipidemic activity. Costunolide inhibits RANKL-induced osteoclast differentiation by suppressing RANKL-mediated c-Fos transcriptional activity; it inhibits IL-1beta gene expression by blocking the activation of MAPKs and DNA binding of AP-1; it also induces the ROS-mediated mitochondrial permeability transition and resultant cytochrome c release,. Costunolide is a germacranolide with anthelminthic, antiparasitic and antiviral activities. It has a role as a metabolite, an antiinfective agent, an antiparasitic agent, an anthelminthic drug, an antineoplastic agent and an antiviral drug. It is a heterobicyclic compound and a germacranolide.
553-21-9 98% Costunolide