Eurycomanone has anti-cancer activity, it is cytotoxic on HepG2 cells by inducing apoptosis through the up-regulation of p53 and Bax, and down-regulation of Bcl-2.

Atherosperminine shows cholinesterase inhibitory activity against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). Atherosperminine shows strong anti-plasmodial activity against Plasmodium falciparum, with the IC50 value of 5.80 uM, it also shows antioxidant activity in a DPPH assay with the IC50 value of 54.53 ug/mL. Atherosperminine exerts a non-specific relaxant effect on the trachealis, its major mechanism of action appears to be inhibition of cAMP phosphodiesterase.

Ailanthone is a triterpenoid. Ailanthone has anti-inflammatory, anti-HIV, anti-malarial, anti-allergic, antiulcer and antimicrobial activities; it also has potent antineoplastic activity against hepatocellular carcinoma (HCC), it can inhibit huh7 cancer cell growth via cell cycle arrest and apoptosis in vitro and in vivo. Ailanthone has significant pre-emergence herbicide activity , is directly correlated to Ailanthone concentration. Ailantone (Δ 13 Dehydrochaparrinone) is an effective androgen receptor (AR) inhibitor, with IC50 values of 69 nM for intact androgen receptors and 309 nM for sustained active splicing variants.

1-Methyl-2-nonyl-4(1H)-quinolinone is a member of quinolines.

Hydroquinidine can prevents life-threatening arrhythmic events in patients with short QT syndrome.