| Catalog No | Product Description | CAS No. | Purity | Structural Formula |
|---|---|---|---|---|
| BP0455 |
Daurisoline
Daurisoline is a hERG inhibitor and also an autophagy blocker.Daurisoline has antiarrhythmic effects, it( at concentrations below 30 uM) exerts a blocking effect on hERG, but does not affect the expression and function of the hERG channel, it also can inhibit early afterdepolarizations (EADs) which may be associated with its blockade effects on I(Ca-L). Daurisoline and its isomers show cytoprotective effects on ischemic injury in cultured pheochromocytoma (PC12) cells, which are mediated by blocking Ca2+ influx into cells.
|
70553-76-3 | 98% |
|
| BP0117 |
Acetylcorynoline
Acetylcorynoline is a benzophenanthridine alkaloid.
Acetylcorynoline has anti-inflammatory properties, it also has potential to improve parkinson's disease, it may exert its effects by decreasing egl-1 expression to suppress apoptosis pathways and by increasing rpn5 expression to enhance the activity of proteasomes. Acetylcorynoline may be one of the potent immunosuppressive agents through the blockage of dendritic cells maturation and function. It has protective action against experimental liver injury in mice.
Acetylcorynoline is a major alkaloid extracted from Corydalis bungeana, which has anti-inflammatory effects.
|
18797-80-3 | 98% |
|
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