10-Gingerol is a monomethoxybenzene, a member of phenols and a beta-hydroxy ketone. 10-Gingerol is an AMPK agonist found in fresh ginger rhizome oil resin, with anti-inflammatory, antioxidant, and anti proliferative activities. 10-Gingerol inhibits neointimal hyperplasia and suppresses the proliferation of vascular smooth muscle cells. The IC50 value of 10-Gingerol for DPPH radical scavenging activity is 10.47 μ M, for superoxide radical scavenging activity is 1.68 μ M, and for hydroxyl radical scavenging activity is 1.35 μ M. 10 Gingerol has an inhibitory effect on the proliferation of MDA-MB-231 tumor cell line, with an IC50 value of 12.1 μ M. 10-Gingerol inhibits proliferation, migration, invasion, and induces apoptosis by targeting the PI3K/Akt signaling pathway in MDA-MB-231/IR cells. 10-Gingerol is expected to be used in research on ulcerative colitis. 10-Gingerol has anti-cancer, anti-neuroinflammatory, and anti-bacterial effects, it effectively inhibits the growth of the oral pathogens, and inhibits exogenous ghrelin deacylation.10-Gingerol induces [Ca2+]i rise by causing Ca2+ release from the endoplasmic reticulum and Ca2+ influx from non-L-type Ca2+ channels in SW480 cancer cells.10-Gingerol-induced apoptosis was accompanied by phosphorylation of the mitogen-activated protein kinase (MAPKs) family, c-Jun N-terminal kinase (JNK), p38 MAPK (p38), and extracellular signal-regulated kinase (ERK).