1-O-Acetylbritannilactone has anticancer activity, it suppresses angiogenesis and lung cancer cell growth possibly via regulating the VEGFR-Src-FAK signaling, it also can combine with gemcitabine elicits a potent apoptosis of lung cancer cell. 1-O-Acetylbritannilactone may serve as a novel therapeutic intervention for various cardiovascular diseases, including chronic ischemia, by regulating VEGF signaling and modulating angiogenesis; it is a potent inhibitor of LPS-stimulated VSMC inflammatory responses through blockade of NF-kappaB activity and inhibition of inflammatory gene COX-2 expression. 1-O-Acetylbritannilactone may act as potent natural skin-lightening agents, it exhibits anti-melanogenic activity by suppression of tyrosinase expression via ERK and Akt signaling.

11-Keto-beta-boswellic acid, a novel Nrf2 activator, and a selective 5-lipoxygenase (5-LOX) inhibitor; it exerts dose dependent cardioprotective effect manifested by dose-dependent reduction in serum lactate dehydrogenase; and it can increase the Nrf2 and HO-1 expression, which provides protection against oxygen and glucose deprivation (OGD)-induced oxidative insult. 11-Keto-beta-boswellic acid possesses significant anti-inflammatory, and anti-tumoral activities. 11-Keto-beta-boswellic acid is a pentacyclic triterpenoid acid derived from the oil resin of the bark of the Boswellia serrate tree, commonly known as Indian Frankincense. 11-Keto-beta-boswellic acid has anti-inflammatory activity, mainly due to its inhibition of 5-lipoxygenase (5-LOX), leukotriene, NF - κ B activation, and tumor necrosis factor alpha production.

3,4-dimethoxybenzoic acid is a member of the class of benzoic acids that is benzoic acid substituted by methoxy groups at positions 2 and 3. It has a role as an allergen and a plant metabolite. It derives from a hydride of a benzoic acid.

Asiatic acid is a pentacyclic triterpenoid that is ursane substituted by a carboxy group at position 28 and hydroxy groups at positions 2, 3 and 23 (the 2alpha,3beta stereoisomer). It is isolated from Symplocos lancifolia and Vateria indica and exhibits anti-angiogenic activity. It has a role as a metabolite and an angiogenesis modulating agent. It is a monocarboxylic acid, a pentacyclic triterpenoid and a triol. It is a conjugate acid of an asiatate. It derives from a hydride of an ursane. Asiatic acid shows antihyperlipidemic, anti-inflammatory, antioxidant, and anti-tumorigenesis effects, it inhibits NLRP3 inflammasome activation, NO and COX-2 signals. Asiatic acid inhibits the expression NDR1/2 kinase and promotes the stability of p21WAF1/CIP1 protein through attenuating NDR1/2 dependent phosphorylation of p21WAF1/CIP1 in HepG2 cells. Asiatic acid， It is a pentacyclic triterpenoid found in Centella asiatica, which has anti-cancer activity. Asiatic acid can induce apoptosis in melanoma cells and has a barrier protective effect on human aortic endothelial cells (HAEC). Asiatic acid also has anti-inflammatory activity and can inhibit endothelial barrier dysfunction induced by tumor necrosis factor (TNF) - α. Asiatic acid also inhibits NLRP3 inflammasome activation and NF - κ B pathway, effectively suppressing inflammation in rats, and has neuroprotective effects in a rat spinal cord injury (SCI) model.

Ginsenoside Rh4 is a rare saponin obtained from Panax notoginseng. Ginsenoside Rh4 activates Bax, caspase 3, caspase 8, and caspase 9. Ginsenoside Rh4 also induces autophagy. Ginsenoside Rh4 could be safely used as adjuvant with low or non-haemolytic effect; it has cytotoxic activity and its aglycone against cancer cell lines.

3-O-Acetyloleanolic acid exhibits anti-angiogenic effects, it inhibits proliferation, migration and tube formation of umbilical vein endothelial cells (HUVECs) in a dose-dependent manner; it can inhibit VEGF-A-induced lymphangiogenesis and lymph node metastasis in an oral squamous cell carcinoma animal model. 3-O-Acetyloleanolic acid. 3-O-Acetyloleanolic acid is a type of oleanolic acid extracted from Vigna sinensis K. seeds, which can induce cancer cell apoptosis and has anti angiogenic effects.

Columbianetin acetate is an acetate ester obtained by formal acetylation of the tertiary hydroxy group of 2-[(8S)-2-oxo-8,9-dihydro-2H-furo[2,3-h][1]benzopyran-8-yl]propan-2-ol. It has a role as a plant metabolite. It is a furanocoumarin and an acetate ester. Columbianetin may be helpful in regulating mast cell-mediated allergic inflammatory responses, the absorption of columbianetin acetate is a passive diffusion process without pH-dependent.

Alpha Typerone is associated with downregulation of Cox-2, IL-6, Nck-2, Cdc42, and Rac1 expression, thereby reducing inflammatory response.

Saikogenin D possesses a dual effect: an inhibition of A23187-induced PGE2 production without a direct inhibition of cyclooxygenase activity; and an elevation of [Ca2+]i that is attributed to Ca2+ release from intracellular stores. Saikogenin D has immunomodulatory effect, it can attenuate IL-6 production in LPS-stimulated alveolar macrophages of B6 more than in that of BALB.

Alpha-Hederinis a triterpenoid saponin that is hederagenin attached to a 2-O-(6-deoxy-alpha-L-mannopyranosyl)-alpha-L-arabinopyranosyl residue at position 3 via a glycosidic linkage. It has been isolated from the stem bark of Kalopanax pictus. It has a role as an anti-inflammatory agent and a plant metabolite. It is a pentacyclic triterpenoid, a hydroxy monocarboxylic acid, a triterpenoid saponin and a disaccharide derivative. It is functionally related to a hederagenin. alpha-Hederin possesses several biological properties such as antispasmodic, moliscicidic, anthelmithic and inhibiting cell proliferation, it exhibits a strong antiproliferative activity on all stages of development of the parasite by altering membrane integrity and potential in Leishmania. alpha-Hederin has anti-oxidant activity and acute anti-inflammatory activity in carrageenan-induced rat paw edema. alpha-Hederin can increase isoprenaline-induced relaxation indirectly, probably by inhibiting heterologous desensitization induced by high concentrations of muscarinic ligands like. Alpha Hederin (α - Hederin) is a single bridged triterpenoid saponin that has excellent anti-tumor effects on various tumor cells. Alpha Hederin can inhibit gastric cancer cell proliferation, induce apoptosis, and reduce glutathione and reactive oxygen species production by activating mitochondrial dependent pathways.

Cauloside F is a natural product from Caulopyhllum robustum.

Humulone, a bone resorption inhibitor, induces apoptosis may via its antioxidative activity in the premyocytic leukemia cell line HL-60 between 1 and 100 micrograms/ml. Humulone is also a potent angiogenic inhibitor, can inhibit cyclooxygenase-2 and may be a novel powerful tool for the therapy of various angiogenic diseases involving solid tumor growth and metastasis. Humulone also has antioxidant, antispasmodic, antiviral and antibacterial activities. Humulone is an optically active cyclic ketone consisting of 3,5,6-trihydroxycyclohexa-2,4-dien-1-one bearing two 3-methylbut-2-en-1-yl substituents at positions 4 and 6 as well as a 3-methylbutanoyl group at the 2-position. It has a role as an antioxidant, a metabolite, an antibacterial drug and a cyclooxygenase 2 inhibitor. It is a tertiary alpha-hydroxy ketone, a triol, a cyclic ketone, a diketone and an aromatic ketone.

Alisol C Monoacetate is a triterpenoid. Alisol C monoacetate(Alisol C 23-acetate) has antibacterial activity.

Curdione has anti-inflammatory, cancer chemopreventive activities, significant anti-platelet aggregation and antithrombotic activities , the inhibitory mechanism of curdione on platelet aggregation may increase cAMP levels and subsequently inhibit intracellular Ca2+ mobilization. plays an important role in the CYP3A4 inhibitory activity of C. aromatica.