Neomangiferin exhibits antidiabetic and antiosteoporotic actions; it has beneficial effects on high fat diet-induced nonalcoholic fatty liver disease in rats, it also modulates the Th17/Treg balance and ameliorates colitis in mice.

Hypocrellin A, an a natural perylene quinine photosensitizers (PSs), can chelate with heavy metal ions, including Au(III) and Pt(IV), to form a 1:2 complex. Hypocrellin A has light-induced antitumor,antifungal and antiviral activities, it also exerts immunomodulatory effects on MHC-restricted presentation of antigen.

Tsugafolin has weak anti-HIV activity.

Limonin is a widely used dietary supplement, one of the most prevalent citrus limonoids, which has antioxidant, anti-inflammatory, anticancer and anti-human immunodeficiency virus(HIV)activity. It induced a down regulation of TLR-2 ,TLR-4,TNF-α, TNF-α/IL-10,NF-κB and caspase. It showed the potent inhibition of CYP3A4, with IC50 values of 6.20 μM (CYP3A4/testosterone) and 19.10 μM (CYP3A4/midazolam). Limonin is a member of furans, a lactone, an epoxide, a limonoid, an organic heterohexacyclic compound and a hexacyclic triterpenoid. It has a role as a metabolite, a volatile oil component and an inhibitor.

Ganoderic acid B is a chemical marker in quality control of G. lucidum and related products. Ganoderic acid B-containing herbs has potential influence towards therapeutic window of trifluoperazine.Ganoderic acid B has antinociceptive effect; it is moderately active inhibitors against HIV-1 protease with a 50% inhibitory concentration of 0.17-0.23 mM.