| Catalog No | Product Description | CAS No. | Purity | Structural Formula |
|---|---|---|---|---|
| BP1271 |
Sclareolide
Sclareolide demonstrates a good antibacterial activity against Staphylococcus aureus ATCC 25923, Pseudomonas aeruginosa ATCC 27950, Escherichia coli ATCC 25922 and Enterococcus faecalis ATCC 29212. Sclareolide enhances gemcitabine‑induced cell death through mediating the NICD and Gli1 pathways in gemcitabine‑resistant human pancreatic cancer.
|
564-20-5 | 98% |
|
| BP0792 |
Isopimpinellin
Isopimpinellin has chemopreventive effects, it effectively inhibits mouse COH activity (IC50 values 19-40 microM).Isopimpinellin is a new inhibitor against the Leishmania APRT enzyme.
|
482-27-9 | 98% |
|
| BP0099 |
7-Ethyl-10-Hydroxycamptothecin
7-Ethyl-10-Hydroxycamptothecin is a member of the class of pyranoindolizinoquinolines that is (4S)-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-dione bearing two additional ethyl substituents at positions 4 and 11 as well as two additional hydroxy substituents at positions 4 and 9. It is the active metabolite of irinotecan and is ~1000 times more active than irinotecan itself. It has a role as an antineoplastic agent, a drug metabolite, an EC 5.99.1.2 (DNA topoisomerase) inhibitor and an apoptosis inducer.
7-Ethyl-10-hydroxycamptothecin shows cytotoxicity against breast cancer, it efficiently target-bind to the colon and lungs of mice.
|
86639-52-3 | 98% |
|
| BP0146 |
Aloe emodin
Aloe emodin is a dihydroxyanthraquinone that is chrysazin carrying a hydroxymethyl group at position 3. It has been isolated from plant species of the genus Aloe. It has a role as an antineoplastic agent and a plant metabolite. It is an aromatic primary alcohol and a dihydroxyanthraquinone. It is functionally related to a chrysazin.
Aloe emodin (Rhabarberone) is a natural hydroxy anthraquinone with anti-tumor activity. Aloe emodin (Rhacarberone) can bind to mTORC2 and inhibit its kinase activity. Aloe emodin (Rhabarberone) exerts anti proliferative effects and induces cell apoptosis. Aloe emodin (Rhabarberone) also exhibits antiviral activity against influenza A virus.
|
481-72-1 | 98% |
|
| BP2064 |
Dulcoside A
Dulcoside A is a sweetener and has antioxidant activity.
|
64432-06-0 | 98% |
|
| BP1302 |
Shikonin
Shikonin is a natural red naphthoquinone pigment, has antimicrobial, anti-tumor, and anti-inflammatory effects; a purified shikonin preparation is widely used for the production of medicinals, cosmetics, and some food products; shikonin also enters into the antiinflammatory ointment and cream compositions used for the treatment of burns. It can suppress the cell viability, adhesion, invasion and migratory ability of MGC-803 cells through TLR2- or NF-κB-mediated pathway.
|
517-89-5 | 98% |
|
| BP1254 | 5578-73-4 | 98% |
|
|
| BP1657 |
Panaxydol
Panaxydol has anti-cancer activity, can inhibit the growth and apoptosis of cancer cells, the signaling mechanisms involve a [Ca(2+)](i) increase, JNK and p38 MAPK activation, cAMP, MAP kinase and ROS generation through NADPH oxidase and mitochondria. It induces the differentiation in C6 cells, may through a PI 3-K-dependent pathway. Panaxydol is a natural product found in Panax ginseng. It is an epoxide, an acetylenic compound and an olefinic compound.
|
72800-72-7 |
|
|
| BP1480 |
Hypocrellin C
Hypocrellin B is a naphthalenone.
|
149457-83-0 | 98% |
|
| BP1287 |
Senkyunolide A
Senkyunolide A is a useful standard compound for the quality evaluation and chemical differentiation between Rhizoma chuanxiong and Angelica sinensis, and suitable for the analysis of a large number of samples. Senkyunolide A has the vasorelaxation activity in contractions to various contractile agents in rat isolated aorta.
|
63038-10-8 | 98% |
|
| BP0905 |
Lycorine hydrochloride
Lycorine is a toxic crystalline alkaloid found in various Amaryllidaceae species that weakly inhibits acetylcholinesterase (AChE) and ascorbic acid biosynthesis.Lycorine has antiviral, and anti-cancer effects, the mechanisms of Lycorine on the multiple myeloma cell line ARH-77 are associated with G1 phase cell cycle arrest, mitochondrial dysfunction, reactive oxygen species (ROS) generation, ATP depletion, and DNA damage.
|
2188-68-3 | 98% |
|
| BP1105 |
Pimpinellin
Pimpinellin has phototoxic, it acts as antagonist of proteins with GABA receptor activity. Pimpinellin has anti- inflammatory, and cytotoxic activities. Pimpinellin also has anti-bacterial activity, it shows inhibitory activity against Mycobacterium tuberculosis strain H37Ra , with MICs of 812 uM and IC50s of 389 uM.
|
131-12-4 | 98% |
|
| SBP00202 | 705973-69-9 |
|
||
| BP1366 |
Taraxerol acetate
Taraxerol can be used as a lipid biomarker for mangrove input to the SE Atlantic. Taraxerol has potent anti-inflammatory effects,it downregulates the expression of proinflammatory mediators in macrophages by interfering with the activation of TAK1 and Akt, thus preventing NF-κB activation. Taraxerol also has anti-cancer activity, it shows inhibitory effects on AGS cell growth through inducing G2/M arrest and promotion of cell apoptosis, taraxeryl acetate has less effect on cell cycle arrest and apoptosis of AGS cells than taraxerol.
|
2189-80-2 | 98% |
|
| SBP00295 | 252333-71-4 |
|
||
| SBP00214 | 38072-88-7 |
|
||
| SBP00223 | 18457-44-8 |
|
||
| BPC0353 | 62018-77-3 |
|
||
| BP1399 |
Topotecan Hydrochloride
Topotecan hydrochloride, a topoisomerase I inhibitor, capable of inhibiting tumoral growth in animal models of retinoblastoma. Topotecan hydrochloride liposomes loaded CS/β-GP hydrogel could become a potential formulation for improving the antitumor efficacy of Topotecan hydrochloride. Topotecan hydrochloride is a pyranoindolizinoquinoline. It has a role as an antineoplastic agent and an EC 5.99.1.2 (DNA topoisomerase) inhibitor. It contains a topotecan.
|
119413-54-6 | 98% |
|
| SBP03419 | 57457-99-5 |
|
Shenshuai
Wenjing
Hedandan