| Catalog No | Product Description | CAS No. | Purity | Structural Formula |
|---|---|---|---|---|
| BPF9797 |
Hyodeoxycholic acid
Hyodeoxycholic acid is a member of the class of 5beta-cholanic acids that is (5beta)-cholan-24-oic acid substituted by alpha-hydroxy groups at positions 3 and 6. It is a bioactive compound extracted from Calculus bovis. It has a role as a mouse metabolite and a human metabolite. It is a C24-steroid, a bile acid, a member of 5beta-cholanic acids and a 6alpha,20xi-murideoxycholic acid. It is functionally related to a cholic acid. It is a conjugate acid of a hyodeoxycholate. Hyodeoxycholic acid is a secondary bile acid formed in the small intestine by the gut flora, and acts as a TGR5 (GPCR19) agonist, with an EC50 of 31.6 µM in CHO cells. Hyodeoxycholic acid has hypolipidemic effect through regulation of FXR activation, it is a candidate for antiatherosclerotic drug, by significantly increasing the expression of genes involved in cholesterol efflux, such as Abca1, Abcg1,and Apoe,in a macrophage cell line.
|
83-49-8 | 98% |
|
| SBP04340 | 34399-44-5 |
|
||
| BP1767 |
Magnocurarine
Magnocurarine is a natural product from Magnolia officinalis.
|
6801-40-7 | 98% |
|
| BPC0218 | 3423-26-5 |
|
||
| SBP00655 | 390362-53-5 |
|
||
| BP0591 | 73870-35-6 |
|
||
| BP4436 | 1668-85-5 | 98% |
|
|
| BP0750 |
Hypaconitine
Hypaconitine, an active and highly toxic constituent derived from Aconitum species, has anti-inflammatory activity, is widely used to treat rheumatism. It produced neuromuscular blockade by reducing the evoked quantal release, the mechanism of this effect was attributed mainly to blocking of the nerve compound action potential.
|
6900-87-4 | 98% |
|
| SBP03261 | 464-86-8 |
|
||
| BP0741 |
Huperzine B
Huperzine B is a efficient inhibitor of human brain AChE, it can enhance ognitive and protect neuro, may be potentially new drug candidates for Alzheimer's disease therapy.
|
103548-82-9 | 97% |
|
| BP0740 |
Huperzine A
Huperzine A is a sesquiterpene alkaloid isolated from a club moss Huperzia serrata that has been shown to exhibit neuroprotective activity. It is also an effective inhibitor of acetylcholinesterase and has attracted interest as a therapeutic candidate for Alzheimer's disease. It has a role as an EC 3.1.1.7 (acetylcholinesterase) inhibitor, a neuroprotective agent, a nootropic agent and a plant metabolite. Huperzine A is a potent, selective and reversible acetylcholinesterase (AChE) inhibitor and has been widely used in China for the treatment of Alzheimer's disease (AD).Huperzine A induces CYP3A4 expression and activation via PXR dependent pathways, may contribute to drug-drug interactions with ligustrazine and oridonin.
|
102518-79-6 | 98% |
|
| BPC0220 | 532-24-1 |
|
||
| BPC0215 | 35721-92-7 |
|
||
| BP0742 | 163089-71-2 |
|
||
| SBP04384 | 19360-72-6 |
|
||
| BP1538 |
Rhodojaponin V
Rhodojaponin V is a natural product from Rhododendron molle G. Don.
|
37720-86-8 | 98% |
|
| BP0470 |
Delsoline
Delsoline has hypotensive effects.Delsoline is not only effective in preventing ventricular fibrillation and arrythmia, but can raise the intebsity of the threthold of electrical shocks to cause ventricular fibrillation in rabbits, the antiarrythmic effect of it may be mainly attributed to itsganglionic blocking and negative cardiac inotropic effect.
|
509-18-2 | 98% |
|
| BP5062 | 71117-97-0 | 98% |
|
|
| BP4365 |
Lycoramine
Lycoramine is a benzazepine.
|
21133-52-8 | 98% |
|
| SBP02634 | 6880-54-2 |
|
Shenshuai
Wenjing
Hedandan