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Catalog No Product Description CAS No. Purity Structural Formula
BP0086
Mosloflavone
Mosloflavone is an ether and a member of flavonoids. Mosloflavone is an antifungal and radical scavenging 2-hydroxyflavanone, it possesses strong anti-EV71 activity and decreased the formation of visible cytopathic effects, it also inhibits virus replication during the initial stage of virus infection, and inhibits viral VP2 protein expression, thereby inhibiting viral capsid protein synthesis. Mosloflavone shows promising anti-inflammatory activity via inhibition of TNF-α and IL-1β with IC50 values of 16.4 uM and 6.4 uM, respectively; it shows dose-dependent inhibition of TNF-α, IL-1β and iNOS levels in the supernatant of mouse macrophage cell line J774A, it also can be used as a starting point to discover lead structures for treatment of inflammatory and immunomodulatory diseases. Mosloflavone extracted from Scutellaria baicalensis Georgi has anti EV71 activity. Mosloflavone inhibits VP2 virus replication and protein expression during the initial stage of viral infection, as well as suppresses virus VP2 capsid protein synthesis. Mosloflavone is a promising fungicide that can inhibit the virulence and biofilm formation of Pseudomonas aeruginosa
740-33-0 98% Mosloflavone
SBP02658 63768-17-2 12α-Hydroxygrandiflorenic acid