(+)-Pteryxin has muscle-relaxant props, it also shows hepatoprotective and nitric oxide prodn. inhibitory activity.

Piperlonguminine is an efficient depigmenting agent with a novel mechanism of action. It has potent antitumor, antitrypanosomal, anti-hyperlipidemic, anti-platelet and anti-melanogenesis activities. Piperlonguminine obviously improves hepatocyte fatty degeneration of alcoholic fatty liver in mice, it can effectively prevent the occurrence and development of alcoholic fatty liver. (E,E)-Piperlonguminine is a member of benzodioxoles.

Fargesin has anti-inflammatory, anti-cancer, antihypertensive , and anti-bone-resorbing effects, it is widely used in the treatment of managing rhinitis, inflammation, histamine, sinusitis, and headache. Fargesin improves lipid and glucose metabolism in 3T3-L1 adipocytes and high-fat diet-induced obese mice by activating Akt and AMPK in WAT. It as a potential β1 adrenergic receptor antagonist protects the hearts against ischemia/reperfusion injury in rats via attenuating oxidative stress and apoptosis.

Isosakuranin is a glycoside and a member of flavonoids. Isosakuranin is a product from Paliurus ramosissimus.

Benzoylpaeoniflorin is active against cyclooxygenase(COX)-1 and COX-2 enzymes, it can restrain apoptosis of rats with coronary heart diseases by increasing the levels of Bc1-2 and decreasing the levels of Bax. Benzoylpaeoniflorin is a terpene glycoside. It has a role as a metabolite.

Platyconic acid A suppresses the development of respiratory inflammation, hyperresponsiveness, and remodeling by reducing allergic responses, and it may be a potential herbal drug for allergen-induced respiratory disease prevention. Platyconic acid A suppresses PMA-induced MUC5AC mRNA expression by inhibiting NF-κB activation via Akt in A549 cells. Platyconic acid A is a triterpenoid saponin. It has a role as a metabolite.

Coronafacic acid is a ketone.

Silydianin, an active constituent of Silybium marianum, has inhibitory effect on on the in vitro production and release of oxidative products. Silydianin has possible antiinflammatory activity, which regulates caspase-3 activation, affects cell membranes and acts as a free radical scavenger.

5-O-Demethylnobiletin is an ether and a member of flavonoids. 5-0-Demethylnobiletin has anti-inflammatory activity, it may act through a direct inhibition of 5-LOX, without affecting the expression of COX-2. 5-O-Demethylnobiletin is a multi methoxyflavone isolated from Citrus jambhiri Lush. It is a direct inhibitor of 5-LOX (IC50=0.1 μ M) and does not affect the expression of COX-2. 5-O-Demethylnobiletin has anti-inflammatory activity, inhibiting the formation of leukotriene B (4) (LTB4) in rat neutrophils and the release of elastase in human neutrophils, with an IC50 value of 0.35 μ M

Afzelin has several cellular activities such as DNA-protective, antibacterial, antioxidant, and anti-inflammatory as well as UV-absorbing activity and may protect human skin from UVB-induced damage by a combination of UV-absorbing and cellular activities. Afzelin has potenial anti-cancer activity against prostate cancer, the activity is due to inhibition of LIM domain kinase 021 expression, it can inhibit the proliferation of LNCaP and PC302cells, and block the cell cycle in the G002phase. Afzelin can attenuate asthma phenotypes is based on reduction of Th2 cytokine via inhibition of GATA-binding protein 3 transcription factor, which is the master regulator of Th2 cytokine differentiation and production. Afzelin is a glycosyloxyflavone that is kaempferol attached to an alpha-L-rhamnosyl residue at position 3 via a glycosidic linkage. It has a role as an antibacterial agent, an anti-inflammatory agent and a plant metabolite. It is a trihydroxyflavone, a glycosyloxyflavone and a monosaccharide derivative. It is functionally related to a kaempferol. It is a conjugate acid of an afzelin(1-).

Bisabololoxide A induces apoptosis in rat thymocytes.

Eriodictyol-7-O-glucoside and epicatechin appears to be responsible for the antioxidant activity of pistachio skin.Eriodictyol-7-O-glucoside has protective effect on cisplatin-induced toxicity was investigated in a human renal mesangial cell line, HRMC; it also can activate Nrf2/ARE signaling, directly associated with its neuroprotection against oxidative stress-induced ischemic; suggests that targeting the Nrf2/ARE pathway may be a promising approach for therapeutic intervention in stroke. Eriodictyol 7-O-beta-D-glucopyranoside is a flavanone glycoside that is eriodictyol attached to a beta-D-glucopyranosyl residue at position 7 via a glycosidic linkage. It is an Nrf2 activator and provides protection against cisplatin-induced toxicity. It has a role as a radical scavenger and a plant metabolite. It is a beta-D-glucoside, a trihydroxyflavanone, a monosaccharide derivative and a flavanone glycoside. It is functionally related to an eriodictyol.

Norbraylin is a natural product from Toddalia asiatica.