Pellitorine is a potential larvicide with a specific target site and a lead molecule for the control of mosquito populations, it also shows antiprotozoal activity against Plasmodium falciparum (IC50 = 3.3 ug/mL). Pellitorine shows potent antiplatelet aggregation activity, it can suppress expression of inducible NO synthase and cyclooxygenase-2. Pellitorine also shows strong cytotoxic activities against HL60 and MCT-7 cell lines. Pellitorine is a fatty amide. It has a role as a metabolite.

Monocrotaline is a pyrrolizidine alkaloid.

Genipin is an excellent natural cross-linker for proteins, collagen, gelatin, and chitosan cross-linking, can be used as a regulating agent for drug delivery, as the raw material for gardenia blue pigment preparation. It is a novel chemical activator of EBV lytic cycle and a cell permeable inhibitor of uncoupling protein 2 (UCP2). Genipin has antimicrobial,antiviral, antitumor, and anti-inflammatory effects, it is used for choleretic action for liver diseases control and could be used for the treatment of periodontal disease to prevent MMPs expression in periodontal lesion. It shows an antithrombotic effect in vivo due to the suppression of platelet aggregation. Genipin 1-beta-gentiobioside is a terpene glycoside.

Plumbagin is a hydroxy-1,4-naphthoquinone that is 1,4-naphthoquinone in which the hydrogens at positions 2 and 5 are substituted by methyl and hydroxy groups, respectively. It has a role as a metabolite, an antineoplastic agent, an anticoagulant and an immunological adjuvant. It is a hydroxy-1,4-naphthoquinone and a member of phenols.

3-Butylidenephthalide is an isobenzofuranone. 3-Butylidenephthalide has antihyperglycemic effect is due to inhibition of α-glucosidase at the intestinal level, inhibited the activity of yeast-α-glucosidase (IC(50) 2.35 mM) in a noncompetitive fashion with a K(i) of 4.86 mM. It can induce a dose-dependent antinociceptive action in the hot-plate assay, it is also effective for controlling the pain provoked by chemical irritation at the doses of 10 and 31.6 mg/kg. 3-Butylidenephthalide is a phthalic anhydride derivative identified from Ligusticum chuanxiong Hort, with insecticidal activity (LC50 value of 1.56 mg/g for Spodoptera litura larvae).

Dicoumarol is a hydroxycoumarin that is methane in which two hydrogens have each been substituted by a 4-hydroxycoumarin-3-yl group. Related to warfarin, it has been used as an anticoagulant. It has a role as an anticoagulant, an EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor, a vitamin K antagonist and a Hsp90 inhibitor.

1-Cinnamoylpyrrolidine is an olefinic compound. It is functionally related to a cinnamic acid. 1-Cinnamoylpyrrolidine shows inhibitory activity of platelet aggregation in vitro.

Buddlejasaponin IVb(200 uM) can shorten thrombin time (TT) by 20.6 %, suggests that it has hemostasis efficacy.

Plantagoside is a potent inhibitor of the Maillard reaction, it also can inhibit the formation of advanced glycation end products in proteins in physiological conditions and inhibit protein cross-linking glycation. It is also a specific non-competitive inhibitor for jack bean alpha-mannosidase (IC50 at 5 microM). Plantagoside suppresses antibody response to sheep red blood cells and concanavalin A induced lymphocyte proliferation which was measured by [3H]thymidine incorporation. Plantagoside has potential therapeutic applications in the prevention of diabetic complications. Plantagoside is a flavanone glycoside that is (2S)-flavanone substituted by hydroxy groups at positions 5, 7, 4' and 5' and a beta-D-glucopyranosyloxy group at position 3' respectively. It has a role as a plant metabolite. It is a member of 4'-hydroxyflavanones, a beta-D-glucoside, a tetrahydroxyflavanone, a monosaccharide derivative and a flavanone glycoside. It is functionally related to a (2S)-flavanone.

Coumarin is an anticoagulant and photoprotective drug; it also has antiulcerogenic activity, which may influence the secretion control mediated by the parasympathetic system. Coumarin is a potent inducer of aflatoxin B1-aldehyde reductase, has chemoprevention of aflatoxin B1 hepatocarcinogenesis. Coumarin is a chromenone having the keto group located at the 2-position. It has a role as a fluorescent dye, a plant metabolite and a human metabolite.

Isorhamnetin 3-O-galactoside shows antioxidant, anti-inflammatory, neuroprotective,and barrier protective activities, it could be used as a candidate therapeutic for treatment of severe vascular inflammatory diseases.It has potential anticoagulant activity, it possesses antithrombotic and profibrinolytic activity and offers bases for development of a novel anticoagulant. Isorhamnetin 3-O-galactoside is also a 5-lipoxygenase inhibitor, it may have therapeutic potential in skin inflammatory disorders in traditional medicine. Isorhamnetin 3-O-beta-D-galactopyranoside is a glycosyloxyflavone that is isorhamnetin substituted at position 3 by a beta-D-galactosyl residue. It has a role as a metabolite. It is a monomethoxyflavone, a trihydroxyflavone, a beta-D-galactoside, a glycosyloxyflavone and a monosaccharide derivative. It is functionally related to a beta-D-galactose and an isorhamnetin.

Citropten and valproic acid show antiproliferative effects against A2058 human melanoma cells. 5,7-dimethoxy-1-benzopyran-2-one is a member of coumarins.

Glycycoumarin is an estrogen agonist, it shows moderate inhibitory effects against CYP1A2 and CYP2B6. Glycycoumarin has anti-liver cancer, neuroprotective, antioxidant and anti-inflammatory activities. Glycycoumarin has anti-hepatitis C virus (HCV) activity, with the IC(50) value of 8.8, ug/mL. Glycycoumarin has an inhibitory effect on smooth muscle contraction induced by various types of stimulants through the inhibition of PDEs, especially isozyme 3, followed by the accumulation of intracellular cAMP; it also can inhibit hepatocyte lipoapoptosis through activation of autophagy and inhibition of ER stress/GSK-3-mediated mitochondrial pathway. Glycycoumarin is a member of the class of coumarins that is coumarin substituted by a hydroxy group at position 7, a methoxy group at position 5, a prenyl group at position 6 and a 2,4-dihydroxyphenyl group at position 3. Isolated from Glycyrrhiza uralensis, it exhibits antispasmodic activity. It has a role as an antispasmodic drug and a plant metabolite. It is a member of coumarins, a member of resorcinols and an aromatic ether.

Salvianolic acid B is a member of the class of 1-benzofurans that is an antioxidant and free radical scavenging compound extracted from S. miltiorrhiza. It has a role as an antioxidant, an antidepressant, a hypoglycemic agent, an antineoplastic agent, a hepatoprotective agent, an osteogenesis regulator, a neuroprotective agent, an anti-inflammatory agent, an apoptosis inducer, a plant metabolite, a cardioprotective agent and an autophagy inhibitor. Salvianolic acid B is a bioactive compound isolated from the Chinese medicinal herb Danshen, which is used for treating neoplastic and chronic inflammatory diseases in China, it shows a protective action against the ischemia-reperfusion induced injury in rat brain. It inhibited the expression of COX,ERK,TNF-α, NO.

Miglustat is a hydroxypiperidine that is deoxynojirimycin in which the amino hydrogen is replaced by a butyl group. It has a role as an EC 2.4.1.80 (ceramide glucosyltransferase) inhibitor and an anti-HIV agent. It is a member of piperidines and a tertiary amino compound. It is functionally related to a duvoglustat.

Toddalolactone, a natural coumarin, inhibits the activity of recombinant human Plasminogen activator inhibitor-1 (PAI-1) in a dose-dependent manner, yielding an IC50 value of 37.31 ± 3.23 μM.