Daphnoretin is a member of the class of coumarins that is coumarin substituted by a hydroxy group at position 7, a methoxy group at position 6 and a (2-oxo-2H-chromen-7-yl)oxy group at position 3. It has a role as an antiviral agent, a metabolite and an antineoplastic agent. It is an aromatic ether and a hydroxycoumarin. It is functionally related to a coumarin.

Gymnemagenin is a potent and selective antagonist for the β isoform of LXR, it has antihyperglycemic activity, it can be considered further for development into a potent anti-diabetic drug.

Eleutheroside E is a glycoside and a lignan.

Catalpol is a kind of enzyme inhibitors, it has been shown to have antioxidation, anti-inflammation, anti-apoptosis and other neuroprotective properties and plays a role in neuroprotection against hypoxic/ischemic injury, AD and PD in both in vivo and in vitro models.Catalpol regulates cholinergic nerve system function through effect on choline acetyl-transferase not M receptor affinity, it has a wide spectrum of targets including Bcl-2 , PI3K, Akt-eNOS, caspase. Catalpol is an organic molecular entity. It has a role as a metabolite.

Timosaponin AI can inhibit dipeptidyl peptidase-4 (DPP-4) activity in a dose-dependent manner, the DPP-4 inhibitor has been clinically used for the treatment of type 2 diabetes mellitus.

Neoeriocitrin is a flavanone glycoside that is eriodictyol substituted by a 2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl residue at position 7 via a glycosidic linkage. It has a role as a plant metabolite. It is a member of 4'-hydroxyflavanones, a neohesperidoside, a trihydroxyflavanone, a disaccharide derivative and a flavanone glycoside. It is functionally related to an eriodictyol. Neoeriocitrin has antioxidant capacity, it could rescue the inhibition effect of cell differentiation induced by PD98059 to some degree.Neoeriocitrin may be a new promising candidate drug for treatment of osteoporosis.

Marein shows neuroprotective effect on PC12 cell damage induced by methylglyoxal, which is due to a reduction of damage to mitochondria function and activation of the AMPK signal pathway, it may be a potent compound for preventing/counteracting diabetic encephalopathy. Marein can improve insulin resistance induced by high glucose in HepG2 cells through CaMKK/AMPK/GLUT1 to promote glucose uptake, through IRS/Akt/GSK-3β to increase glycogen synthesis, and through Akt/FoxO1 to decrease gluconeogenesis. Marein shows antioxidant activity, it shows Histone deacetylase enzymes (HDACs) inhibitory activity and it also can inhibit TNFα-induced NF-κB activation.

Licoflavone A is a member of flavones.

Eriocitrin is a disaccharide derivative that consists of eriodictyol substituted by a 6-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage. It has a role as an antioxidant. It is a member of 4'-hydroxyflavanones, a rutinoside, a trihydroxyflavanone, a member of 3'-hydroxyflavanones, a disaccharide derivative and a flavanone glycoside. It is functionally related to an eriodictyol. Eriocitrin is powerful antioxidative flavonoid, it can prevent oxidative damages caused by acute exercise-induced oxidative stress, it also has lipid-lowering effect in rats on a high-fat and high-cholesterol diet. Eriocitrin is a potent inhibitor of human carbonic anhydrase VA isozyme.

2''-O-Galloylhyperin is a glycoside and a member of flavonoids.

Oleuropein is a secoiridoid glycoside that is the methyl ester of 3,4-dihydro-2H-pyran-5-carboxylic acid which is substituted at positions 2, 3, and 4 by hydroxy, ethylidene, and carboxymethyl groups, respectively and in which the anomeric hydroxy group at position 2 has been converted into its beta-D-glucoside and the carboxylic acid moiety of the carboxymethyl substituent has been converted to the corresponding 3,4-dihydroxyphenethyl ester (the 2S,3E,4S stereoisomer). Oleuropein exhibits anti-ischemic, antioxidative, hypolipidemic, in vitro antimycoplasmal , anti-inflammatory, and anti-cancer effects., it also may be helpful in the prevention of diabetic complications associated with oxidative stress. Oleuropein prevents oxidative myocardial injury induced by ischemia and reperfusion, and reduces viremia in duck hepatitis B virus (DHBV)-infected ducks. Oleuropein reduces TLR and MAPK signaling.

Genkwanin has antitumor, and anti-inflammatory activities, it enhances host immunity, decreases the inflammatory cytokine levels, and regulates the miR-101/MKP-1/MAPK pathway.Genkwanin may have anti-skin ageing activity, it can up-regulate the transcriptional activation of human type vii collagen gene promoter, stimulating the formation of anchoring fibrils at the basement membrane zone in skin contributed to preventing skin ageing; it also induces a decrease of melanin synthesis by inhibiting tyrosinase activity, it could as skin whitening agent in cosmetic preparations. Genkwanin is a monomethoxyflavone that is apigenin in which the hydroxy group at position 7 is methylated. It has a role as a metabolite. It is a monomethoxyflavone and a dihydroxyflavone. It is functionally related to an apigenin. It is a conjugate acid of a genkwanin(1-).

Yuanhuadine is a natural product found in Daphne genkwa. It has a role as a metabolite.

Flavanomarein demonstrates potent antioxidative property, including free radical scavenging activity, inhibition of lipid peroxidation, as well as lipid‑lowering effects in human HepG2 hepatocellular carcinoma cells treated with free fatty acids (FFAs).

Isorhamnetin 3-O-beta-D-glucopyranoside is a glycosyloxyflavone that is isorhamnetin substituted at position 3 by a beta-D-glucosyl residue. It has a role as a metabolite. It is a beta-D-glucoside, a monomethoxyflavone, a trihydroxyflavone, a glycosyloxyflavone and a monosaccharide derivative. It is functionally related to a beta-D-glucose and an isorhamnetin.