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XBP1

X-box binding protein 1 (XBP1) is a crucial transcription factor involved in the unfolded protein response (UPR) in the endoplasmic reticulum. It plays a central role in maintaining cellular proteostasis by regulating gene expression essential for protein folding, secretion, and degradation. XBP1 activation is critical for the adaptive response to ER stress and is implicated in various physiological processes and pathologies, including cancer, metabolic diseases, and immune responses.
Catalog No Product Description CAS No. Purity Structural Formula
BP2240
(9Z,11E)-13-Oxo-9,11-octadecadienoic Acid
13-oxo-9Z,11E-ODE is an oxooctadecadienoic acid that consists of 9Z,11E-octadecadienoic acid bearing an additional 13-keto substituent. In addtion it has been found as a natural product found in Carthamus oxyacantha. It has a role as a metabolite and a mouse metabolite. It is functionally related to a 13-HODE. It is a conjugate acid of a 13-oxo-9Z,11E-ODE(1-).
54739-30-9 (9Z,11E)-13-Oxo-9,11-octadecadienoic Acid
BP0275
Bilobetin
Bilobetin treatment ameliorates hyperlipidaemia, lipotoxicity and insulin resistance in rats by stimulating PPARα-mediated lipid catabolism.
521-32-4 98% Bilobetin
BP1332
Soyasaponin Bb
Soyasaponin I is a triterpenoid saponin that is composed of soyasapogenol B having an alpha-L-rhamnopyranosyl-(12)-beta-D-galactopyranosyl-(12)-beta-D-glucopyranosiduronic acid moiety attached at the 3-position via a glycosidic linkage. It has a role as a sialyltransferase inhibitor. It is a pentacyclic triterpenoid, a triterpenoid saponin, a carbohydrate acid derivative and a trisaccharide derivative. It is functionally related to a soyasapogenol B. Soyasaponin Bb can suppress Eca-9706 cell growth, reverse effects on over expression of c-met, VEGF, and induce cell apoptosis through inhibiting HDAC1-NF-kappaB and activating PETEN and caspase-3 signaling pathways.
51330-27-9 98% Soyasaponin Bb
BP1331
Soyasaponin Ba
Soyasaponins(Aa, Ab, Af, Ba, Bb, and Bb') together with their derivatives may represent viable candidates for effective vaccine adjuvants due to their higher and lower or non-haemolytic effects.Soyasaponins Ab and Bb prevent scopolamine-induced memory impairment in mice without the inhibition of acetylcholinesterase.
114590-20-4 98% Soyasaponin Ba
BP1328
Soyasapogenol A
Soyasapogenol A shows estrogenic and hepatoprotective activities, it directly prevents apoptosis of hepatocytes, and secondly, inhibits the elevation of plasma TNF-α, which consequently resulted in the prevention of liver damage in the concanavalin A-induced hepatitis model. Soyasapogenol A is a pentacyclic triterpenoid that is oleanane containing a double bond between positions 12 and 13 and substituted by hydroxy groups at the 3beta, 21beta, 22beta and 24-positions. It derives from a hydride of an oleanane.
508-01-0 98% Soyasapogenol A
BP0367
Cinobufotalin
Cinobufotalin is a main cardiac toxin in toad, it is a novel anti-HCC agent, it induces growth inhibition and apoptosis in cultured HCC cells through ceramide production. Cinobufotalin is also an effective reversal agent for the multidrug resistance of tumors, it can reverse the adriamycin-resistance in Raji/ADR cells and the expression of P-gp and MRP-1 proteins. Cinobufotalin can promote the dendritic cells(DCs) derived from peripheral blood of patients with chronic hepatitis B to mature and effectively enhance its(the DCs') capabilities, therefore the treatment of cinobufotalin may potentiate the antiviral immunity of the patients with chronic hepatitis B(CHB).
1108-68-5 98% Cinobufotalin
BP1329
Soyasapogenol B
Soyasapogenol B is a pentacyclic triterpenoid that is oleanane containing a double bond between positions 12 and 13 and substituted by hydroxy groups at the 3beta, 22beta and 24-positions. It derives from a hydride of an oleanane. Soyasapogenol B has anti-cancer, hypocholesterolemic, anticomplementary, hepatoprotective effects, it inhibits proliferation of cultured Hep-G2.
595-15-3 98% Soyasapogenol B
BP0052 873001-54-8 98% 3,29-Dibenzoyl rarounitriol
BP3088
Bruceantin
Bruceantin has antiviral activity, it can inhibit pepper mottle virus in pepper; it also shows high antimalarial activity. Bruceantin is an effective agent in controlling the proliferation, viability and migration of multiple myeloma cancer stem cells (CSCs) as well as angiogenesis in vitro. Bruceantin exhibits NF-κB p65 inhibition, and cytotoxic potential against HT-29, HeLa, and HL-60 cells .
41451-75-6 98% Bruceantin
BP2037 183374-16-5 Siraitic acid B
BP1321
Solanesol
Solanesol is a nonaprenol that is hexatriaconta-2,6,10,14,18,22,26,30,34-nonaen-1-ol substituted by 9 methyl groups at positions 3, 7, 11, 15, 19, 23, 27, 31 and 35 (the all-trans0stereoisomer). It has a role as a plant metabolite. It is a primary alcohol and a nonaprenol. Solanesol can effectively scavenge lipid radicals to block lipid peroxidation, and inhibit effects on tyrosinase; it also can protect ethanol-induced L02 cell damage, which might be attributed to the activation of HO-1 and Hsp70.
13190-97-1 98% Solanesol
BP1330
Soyasaponin Aa
Soyasaponin Aa and soyasaponin Ab dose-dependently markedly inhibit adipocyte differentiation and expression of various adipogenic marker genes, through the downregulation of the adipogenesis-related transcription factors PPARγ and C/EBPα in 3T3-L1 adipocytes.
117230-33-8 98% Soyasaponin Aa
BP0251
Berberine
Berberine has neuroprotective, antidepressant, antineoplastic, and anti- fibrosis activities; it is a potent oral hypoglycemic agent with beneficial effects on lipid metabolism, it may as a broad-spectrum anti-microbial medicine, a complementary therapeutic agent for HIV/AIDS; it also may be one of the targeted therapeutic agents that can restore barrier function in intestinal disease states.Berberine is used in histology for staining heparin in mast cells. As a natural dye, berberine has a colour index of 75160. Berberine is a berberine alkaloid, an organic heteropentacyclic compound, an alkaloid antibiotic and a botanical anti-fungal agent. It has a role as a geroprotector, an antioxidant, a metabolite, a hypoglycemic agent, an EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor, an antineoplastic agent, an antilipemic drug, an EC 3.1.1.8 (cholinesterase) inhibitor, an EC 3.1.1.7 (acetylcholinesterase) inhibitor, an EC 1.1.1.21 (aldehyde reductase) inhibitor, an EC 3.1.1.
2086-83-1 98% Berberine
BP1842
Lanosterol
Lanosterol is a tetracyclic triterpenoid that is lanosta-8,24-diene substituted by a beta-hydroxy group at the 3beta position. It is the compound from which all steroids are derived. It has a role as a mouse metabolite, a Saccharomyces cerevisiae metabolite, a plant metabolite, a bacterial metabolite and a human metabolite. It is a 14alpha-methyl steroid, a tetracyclic triterpenoid and a 3beta-sterol. It derives from a hydride of a lanostane. Lanosterol is a key triterpenoid intermediate in the biosynthesis of Cholesterol. Lanosterol induces mild depolarization of mitochondria and promotes autophagy, it is indicative of altered Lanosterol metabolism during PD pathogenesis. 10 μM Lanosterol during IVM in medium without serum and bases on recombinant human chorionic gonadotrophin has a positive effect on maturation of prepubertal ewe oocytes.
79-63-0 97% Lanosterol
BP2405 55057-29-9 95% β-Sitosterol 3-O-galactopyranoside
BP3016 155801-00-6 95% 25-methoxyalisol A
BP5079 2221029-54-3 98% 16β-Hydroperoxyalisol B 23-acetate
BP0926
Maslinic acid
Maslinic acid is a pentacyclic triterpenoid that is olean-12-ene substituted by hydroxy groups at positions 2 and 3 and a carboxy group at position 28 (the 2alpha,3beta stereoisomer). It is isolated from Olea europaea and Salvia canariensis and exhibits anti-inflammatory, antioxidant and antineoplastic activity. It has a role as an antioxidant, an antineoplastic agent, an anti-inflammatory agent and a plant metabolite. It is a pentacyclic triterpenoid and a dihydroxy monocarboxylic acid.
4373-41-5 98% Maslinic acid
BP2295
β-Sitosteryl acetate
Beta-sitosterol 3-O-acetate is a steroid ester obtained by the formal condensation of the hydroxy group of beta-sitosterol with acetic acid. It has been isolated from the mycelia of Cordyceps sinensis. It has a role as a plant metabolite and a fungal metabolite. It is an acetate ester and a steroid ester. It is functionally related to a sitosterol. It derives from a hydride of a stigmastane.
915-05-9 95% β-Sitosteryl acetate
BP2374 1064-06-8 98% Pentaacetylquercetin