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GP6

Glycoprotein VI (GP6) is a key platelet surface receptor that plays a critical role in primary hemostasis and thrombosis. It is the primary signaling receptor for collagen, initiating platelet activation, adhesion, and aggregation upon vascular injury. GP6 mediates signal transduction pathways essential for thrombus formation, making it a significant target in understanding and managing thrombotic disorders. Its interaction with collagen is crucial for stabilizing platelet adhesion and promoting robust clot formation.
Catalog No Product Description CAS No. Purity Structural Formula
BP3922
Yadanziolide A
Yadanziolide A shows strong antiviral activity.
95258-14-3 98% Yadanziolide A
BP0114
Acacetin
Acacetin is a monomethoxyflavone that is the 4'-methyl ether derivative of apigenin. It has a role as an anticonvulsant and a plant metabolite. It is a monomethoxyflavone and a dihydroxyflavone. It is functionally related to an apigenin. It is a conjugate acid of a 5-hydroxy-2-(4-methoxyphenyl)-4-oxo-4H-chromen-7-olate. Acacetin is an atrium-selective agent that prolongs the atrial effective refractory period without prolonging the corrected QT interval and effectively prevents atrial fibrillation (AF) in anesthetized dogs after intraduodenal administration. Acacetin has anti-cancer, anti-mutagenic, spasmolytic and antinociceptive, anti-inflammatory and anti-peroxidative effects. Acacetin is an orally effective flavonoid derived from Dendranthema morifolium. Acacetin stops in the ATP binding pocket of PI3K γ. Acacetin causes cancer cell cycle arrest and induces apoptosis and autophagy. Acacia extract has effective anti-cancer and anti-inflammatory activities, and has the potential for research on pain related diseases.
480-44-4 98% Acacetin
BP1250
Salvianolic acid D
Salvianolic acid and notoginseng triterpenes can promote EA-hy926 and expression of protein, have protective effects on angiogenesis in EA-hy926 cells in vitro.
142998-47-8 95% Salvianolic acid D
SBP04107
Asebogenin
Asebogenin has anti-bacterial activity, it shows inhibitory activity against S. aureus and methicillin-resistant S. aureus (IC50 of 10 and 4.5 micrograms/ml, respectively); it shows antiplasmodial activities against both a chloroquine-sensitive and a resistant strain of Plasmodium falciparum. Asebogenin can inhibit the proliferation of murine B cells. Asebogenin is a member of the class of dihydrochalcones that is the 4'-methyl ether derivative of phloretin. It has a role as a plant metabolite. It is functionally related to a phloretin.
520-42-3 98% Asebogenin
BP0674
glaucocalyxin A
Glaucocalyxin A could potentially be developed as an antiplatelet and antithrombotic agent, can inhibit platelet p-selectin secretion and integrin activation by convulxin, is a GPVI selective ligand. Glaucocalyxin A has regulation of microglia activity, can attenuate lipopolysaccharide -stimulated neuroinflammation through NF-κB and p38 MAPK signaling pathways.Glaucocalyxin A may become a potential anti-fibrotic agent in Idiopathic pulmonary fibrosis (IPF) management, it can effectively ameliorate pulmonary fibrosis through the antagonism of leukocyte infiltration and proinflammatory cytokine production.
79498-31-0 98% glaucocalyxin A
SBP03048
Piperlotine A
Piperlotine A shows potent antiplatelet aggregation activity.
389572-70-7 98% Piperlotine A
BP4430 117210-12-5 98% Anemarrhenasaponin A2
BP4420
Xanthopurpurin
Xanthopurpurin shows antiviral activity, it can effectively inhibit rotavirus multiplication by promoting virus-induced apoptosis in MA-104 cells. Xanthopurpurin shows mainly strong inhibition of collagen-induced platelet aggregation. Xanthopurpurin is a dihydroxyanthraquinone. It has a role as a metabolite.
518-83-2 98% Xanthopurpurin
BP4502
Pseudojervine
Pseudojervine is a steroid saponin.
36069-05-3 98% Pseudojervine