Yuanhuadine is a natural product found in Daphne genkwa. It has a role as a metabolite.

Gomisin D is a natural product from Schizandra chinensis.

Hypocrellin A, an a natural perylene quinine photosensitizers (PSs), can chelate with heavy metal ions, including Au(III) and Pt(IV), to form a 1:2 complex. Hypocrellin A has light-induced antitumor,antifungal and antiviral activities, it also exerts immunomodulatory effects on MHC-restricted presentation of antigen.

Isobavachin can stimulate osteoblasts proliferation and differentiation; it also can facilitate mouse embryonic stem cells differentiating into neuronal cells, the mechanism involved protein prenylation and, subsequently, phos-ERK activation and the phos-p38 off pathway. Isobavachin possesses estrogen-like activity in MCF-7/BOS cells, it can significantly stimulate the proliferation of MCF-7/BOS cells in a dose-dependent manner. Isobavachin has cytotoxic effects on H4IIE hepatoma and metabolically poorly active C6 glioma cells.

7-Epitaxol is the major derivative of taxol found in cells and taxol (paclitaxel) is a well-known natural-source cancer drug.

Dulcoside A is a sweetener and has antioxidant activity.

Licarin A and (-)-Licarin A are promising compounds that could be used for the development of schistosomicidal and trypanocidal agents; Licarin A presents effect against Leishmania (Leishmania) major associated with immunomodulation in vitro; (-)-Licarin A has antimycobacterial activity, represents a potentially active anti-tuberculosis agent to treat MDR M. tuberculosis and NTM strains.Licarin A significantly protects primary cultured neuronal cells against glutamate-induced oxidative stress, via antioxidative activities.

Cucurbitacin B is a cucurbitacin in which a lanostane skeleton is multi-substituted with hydroxy, methyl and oxo substituents, with unsaturation at positions 5 and 23; a hydroxy function at C-25 is acetylated. It is a tertiary alpha-hydroxy ketone, a cucurbitacin and a secondary alpha-hydroxy ketone. It derives from a hydride of a lanostane. Cucurbitacin B, an effective HIF-1 inhibitor, has antitumor activity, it inhibits proliferation and induces apoptosis via STAT3 pathway inhibition in A549 lung cancer cells. It inhibited AKT signaling activation through up-regulation of PTEN.

Hederasaponin B has antiviral activity, via inhibiting the viral VP2 protein expression and blocking viral capsid protein synthesis. It also has antitumor activity, and it inhibits the superoxide generation induced by arachidonic acid (AA).

Cornoside and Iridoids are chemosystematic markers.

Sophoraflavanone G is a tetrahydroxyflavanone having a structure of naringenin bearing an additional hydroxyl substituent at position 2' as well as a (2R)-5-methyl-2-(prop-1-en-2-yl)hex-4-en-1-yl (lavandulyl) substituent at position 8'. It has a role as an antioxidant, an antimicrobial agent, an antimalarial and a plant metabolite. It is a member of 4'-hydroxyflavanones, a (2S)-flavan-4-one and a tetrahydroxyflavanone. It is functionally related to a (S)-naringenin. Kushenol F is a tyrosinase inhibitor, it shows significant inhibitory effects on monoamine oxidase ( in a dose-dependent manner with IC50 values of 69.9 microM). Kushenol F preferentially inhibits the MAO-B activity than MAO-A activity with the IC50 values of 63.1 and 103.7 microM, respectively.

Damulin A and Damulin B as potential activators of AMP-activated protein kinase (AMPK) from Gynostemma pentaphyllum, which may contribute to beneficial effect of G. pentaphyllum on glucose and lipid metabolism.

Embelin is a member of the class of dihydroxy-1,4-benzoquinones that is 2,5-dihydroxy-1,4-benzoquinone which is substituted by an undecyl group at position 3. Isolated from Lysimachia punctata and Embelia ribes, it exhibits antimicrobial, antineoplastic and inhibitory activity towards hepatitis C protease. It has a role as an antimicrobial agent, an antineoplastic agent, a hepatitis C protease inhibitor and a plant metabolite. Embelin is an inhibitor of X-linked inhibitor of apoptosis (XIAP) with IC50 of 4.1 μM in a cell-free assay.Embelin has antitumor, antioxidant and anti-inflammatory activities. Embelin can enhance TRAIL-induced cell apoptosis through DR4 and DR5 upregulation and decrease IL-6-induced STAT3 phosphorylation, that combination of low-toxicity Embelin and TRAIL may become as a potential antileukemia strategy.

Topotecan hydrochloride, a topoisomerase I inhibitor, capable of inhibiting tumoral growth in animal models of retinoblastoma. Topotecan hydrochloride liposomes loaded CS/β-GP hydrogel could become a potential formulation for improving the antitumor efficacy of Topotecan hydrochloride. Topotecan hydrochloride is a pyranoindolizinoquinoline. It has a role as an antineoplastic agent and an EC 5.99.1.2 (DNA topoisomerase) inhibitor. It contains a topotecan.

Licarin B can improve insulin sensitivity via PPARγ and activation of GLUT4 in the IRS-1/PI3K/AKT pathway in 3T3-L1 adipocytes, it as a promising bioactive for insulin resistance and associated complications through its partial PPARγ activity.