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DPP4

Dipeptidyl peptidase-4 (DPP4), also known as CD26, is a ubiquitously expressed serine protease found on cell surfaces and in soluble form. It plays a crucial role in glucose homeostasis by inactivating incretin hormones, such as GLP-1 and GIP, which stimulate insulin secretion. Inhibition of DPP4 activity prolongs the action of incretins, leading to improved glycemic control, making it a significant therapeutic target for type 2 diabetes mellitus. Beyond its metabolic functions, DPP4 is involved in immune regulation and various physiological processes.
Catalog No Product Description CAS No. Purity Structural Formula
BP1471
Camelliaside B
Camelliaside B is a natural product from Camellia oleifera Abel. Camelliaside b is a glycoside and a member of flavonoids.
131573-90-5 98% Camelliaside B
BP2399 698393-97-4 98% 6-O-cinnamoyl-D-glucopyranose
BP5286 2366153-27-5 98% 1,6,8-Trihydroxy-2,7-dimethoxy-3-methylanthraquinone
BP1394
Timosaponin A1
Timosaponin AI can inhibit dipeptidyl peptidase-4 (DPP-4) activity in a dose-dependent manner, the DPP-4 inhibitor has been clinically used for the treatment of type 2 diabetes mellitus.
68422-00-4 98% Timosaponin A1
BPF2304
Neoeriocitrin
Neoeriocitrin is a flavanone glycoside that is eriodictyol substituted by a 2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl residue at position 7 via a glycosidic linkage. It has a role as a plant metabolite. It is a member of 4'-hydroxyflavanones, a neohesperidoside, a trihydroxyflavanone, a disaccharide derivative and a flavanone glycoside. It is functionally related to an eriodictyol. Neoeriocitrin has antioxidant capacity, it could rescue the inhibition effect of cell differentiation induced by PD98059 to some degree.Neoeriocitrin may be a new promising candidate drug for treatment of osteoporosis.
13241-32-2 98% Neoeriocitrin
BP0554
Eriocitrin
Eriocitrin is a disaccharide derivative that consists of eriodictyol substituted by a 6-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage. It has a role as an antioxidant. It is a member of 4'-hydroxyflavanones, a rutinoside, a trihydroxyflavanone, a member of 3'-hydroxyflavanones, a disaccharide derivative and a flavanone glycoside. It is functionally related to an eriodictyol. Eriocitrin is powerful antioxidative flavonoid, it can prevent oxidative damages caused by acute exercise-induced oxidative stress, it also has lipid-lowering effect in rats on a high-fat and high-cholesterol diet. Eriocitrin is a potent inhibitor of human carbonic anhydrase VA isozyme.
13463-28-0 98% Eriocitrin
BP1669
Fuscaxanthone C
1-Hydroxy-3,6,7-trimethoxy-2,8-diprenylxanthone is a member of xanthones. Fuscaxanthone C is a natural product from Garcinia mangostana.
15404-76-9 98% Fuscaxanthone C
BP5278 113558-11-5 98% Diphylloside A
BP1566
7-O-Methylmangiferin
7-O-Methylmangiferin is a natural product from Polygala tenuifolia.
31002-12-7 98% 7-O-Methylmangiferin
BP5359 3649-76-1 98% Ebelin lactone
BP5211
Clerosterol
Clerosterol as a precursor of cyasterone, isocyasterone and 29-norcyasterone in biosynthesis of phytoecdysteroids of Ajuga hairy roots. Clerosterol exerts its cytotoxic effect in A2058 human melanoma cells by caspases-dependent apoptosis. Clerosterol is a steroid. It derives from a hydride of a stigmastane.
2364-23-0 Clerosterol
BP0922
Mangiferin
Mangiferin is a bioactive compound that demonstrates many health perspectives and has been used to prepare medicinal and food supplements. Mangiferin has anti-steatotic , anti-cancer, anthelminthic and antiallergic activities, it has beneficial effect on the regulation of endothelial homeostasis and could be used in the management of diabetic cardiovascular complications. Mangiferin regulates proliferation and apoptosis in glioma cells by induction of miR-15b and inhibition of MMP-9 expression, it attenuates osteoclastogenesis, bone resorption, and RANKL-induced activation of NF-κB and ERK. Mangiferin is a C-glycosyl compound consisting of 1,3,6,7-tetrahydroxyxanthen-9-one having a beta-D-glucosyl residue at the 6-position. It has a role as an antioxidant, a hypoglycemic agent, an anti-inflammatory agent and a plant metabolite. It is a C-glycosyl compound and a member of xanthones. It is functionally related to a xanthone. It is a conjugate acid of a mangiferin(1-).
4773-96-0 98% Mangiferin
BP2381 51779-95-4 99% 1,2-dierucoyl-sn-glycero-3-phosphocholine
BP5322 64432-09-3 98% Dulcoside C
BP1199
Rebaudioside C
Rebaudioside C belongs to the family of Steviol Glycosides. It is a natural constituent of the plant Stevia rebaudiana Bertoni and used as natural sweeteners to diabetics and others on carbohydrate-controlled diets.
63550-99-2 98% Rebaudioside C
BP0861
Ligupurpuroside C
Ligupurpuroside C can significantly inhibit lipid accumulation in HepG2 cell at the concentration of 50 umol/L.
1194056-33-1 90% Ligupurpuroside C
BP0611
Gallocatechin gallate
(-)-gallocatechin gallate is a gallate ester obtained by formal condensation of the carboxy group of gallic acid with the (3R)-hydroxy group of ()-gallocatechin. A natural product found in found in green tea. It has a role as an EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor, an antineoplastic agent, a plant metabolite and a human xenobiotic metabolite. It is a catechin, a polyphenol and a gallate ester. It is functionally related to a gallic acid and a (-)-gallocatechin. Gallocatechin gallate has strong antioxidative, and anti-obesity activities, it inhibits 3T3-L1 differentiation and lipopolysaccharide induced inflammation through MAPK and NF-κB signaling; it also may have anti-diabetic effects by increasing sensitivity of insulin. Gallocatechin gallate can decrease osteoclastogenesis at 20 microM, it has positive effects on bone metabolism through a double process of promoting osteoblastic activity and inhibiting osteoclast differentiations.
4233-96-9 98% Gallocatechin gallate
BP2415 21681-03-8 98% 8-Methylandrograpanin
BP3975
Salviaflaside
Salviaflaside has antioxidant activity.
178895-25-5 98% Salviaflaside
BP0539
Epicatechin gallate
(-)-epicatechin-3-O-gallate is a gallate ester obtained by formal condensation of the carboxy group of gallic acid with the (3R)-hydroxy group of epicatechin. A natural product found in Parapiptadenia rigida. It has a role as a metabolite, an EC 3.2.1.1 (alpha-amylase) inhibitor and an EC 3.2.1.20 (alpha-glucosidase) inhibitor. It is a catechin, a polyphenol and a gallate ester. It is functionally related to a gallic acid and a (-)-epicatechin. (-)-Epicatechin gallate can effectively stimulates osteoblast differentiation, it has antioxidative effect against lipid peroxidation when phospholipid bilayers are exposed to aqueous oxygen radicals.
1257-08-5 98% Epicatechin gallate