Gossypol is an effective natural antimicrobial agent against a wide range of potential fungal pathogens of cotton.Gossypol shows a significant increase in accumulation of acidic vesicular organelle, is a promising drug that induces autophagic cell death in radioresistant malignant glioma.Gossypol binds to Bcl-xL protein and Bcl-2 protein with Kis of 0.5-0.6 μM and 0.2-0.3 mM, respectively. Gossypol is an aldehyde, a hydroxynaphthalene, a polyphenol and a hexol. It has a role as an antispermatogenic agent, an anti-inflammatory agent and a plant metabolite.

Alpha-Spinasterol is a steroid. It derives from a hydride of a stigmastane. Alpha-Spinasterol is a novel efficacious and safe antagonist of the TRPV1 receptor with anti-inflammatory and antinociceptive effects.Alpha-Spinasterol has a significant therapeutic potential to modulate the development and/or progression of diabetic nephropathy. It also can prevent TP-induced prostatic hyperplasia and may be beneficial in the management of benign prostatic hyperplasia. Alpha Sphingol is an orally administered transient receptor potential vanillic acid 1 (TRPV1) antagonist and an inhibitor of COX-1 and COX-2, with IC50 values of 16.17 μ M and 7.76 μ M, respectively. α - Spinasterol has antibacterial, anti-inflammatory, antidepressant, antioxidant, anti injurious effects, has blood brain barrier permeability, and can improve diabetes in mice.

Brassicasterol is an 3beta-sterol that is (22E)-ergosta-5,22-diene substituted by a hydroxy group at position 3beta. It is a phytosterol found in marine algae, fish, and rapeseed oil. It has a role as a biomarker, an animal metabolite, a marine metabolite, a plant metabolite, a human metabolite, an EC 1.3.1.72 (Delta(24)-sterol reductase) inhibitor, a sterol biosynthesis inhibitor and an algal metabolite. Brassicasterol may be a relevant additional biomarker in Alzheimer's disease (AD).

24,25-dihydrolanosterol is a 3beta-sterol formed from lanosterol by reduction across the C-24C-25 double bond. It has a role as a mouse metabolite and a human metabolite. It is a tetracyclic triterpenoid and a 3beta-sterol. It is functionally related to a lanosterol.