Cytisine is an organic heterotricyclic compound that is the toxic principle in Laburnum seeds and is found in many members of the Fabaceae (legume, pea or bean) family. An acetylcholine agonist, it is widely used throughout Eastern Europe as an aid to giving up smoking. It has a role as a phytotoxin, a nicotinic acetylcholine receptor agonist and a plant metabolite. It is an alkaloid, a lactam, an organic heterotricyclic compound, a bridged compound and a secondary amino compound. Cytisine is a nicotinic acetylcholine receptor agonist, has been widely used for central nervous system (CNS) diseases treatment. It is a partial agonist at alpha4/beta2 nAChRs, and a full agonist at alpha3/beta4 and alpha7 nAChRs, has antidepressant-like properties in several rodent models of antidepressant efficacy.

Yohimbine hydrochloride is an alpha 2-adrenoreceptor antagonist, blocking the pre- and postsynaptic alpha-2 adrenoreceptors and causing an increased release of noradrenaline and dopamine.It is an antagonist to xylazine hydrochloride-ketamine hydrochloride immobilization of white-tailed deer. Yohimbine has been used as a mydriatic and in the treatment of impotence. It is also alleged to be an aphrodisiac.

Allosecurinine is a member of indolizines.

Pseudopelletierine is an azabicycloalkane alkaloid that is 9-azabicyclo[3.3.1]nonane substituted by a methyl group at position 9 and an oxo group at position 3. It is found in pomegranate trees. It has a role as a plant metabolite. It is an alkaloid, an azabicycloalkane, a cyclic ketone and a tertiary amino compound.

Anisodamine, an anticholinergic drug, has antishock effect, which is intimately linked to alpha7nAChR-dependent anti-inflammatory pathway. Anisodamine demonstrates a direct cardiac depressive action at the myocyte level, which may be related to, at least in part, NO production and cholinoceptor antagonism, it causes the changes of structure and function in the transmembrane domain of the Ca(2+)-ATPase from sarcoplasmic reticulum. Anisodamine, a vasoactive drug, can abate endogenous endotoxaemia subsequent to splanchnic vasoconstriction due to hypovolaemia, it alleviates inflammatory damage by significantly reducing the expressions of VEGF and ICAM-1, and shows significant protective effects in an animal model of infusion phlebitis. Anisodamine also inhibits shiga toxin type 2-mediated tumor necrosis factor-alpha production in vitro and in vivo. Scopolamine is a non subtype selective muscarinic and nicotinic acetylcholine receptor antagonist. Scopolamine is used in traditional Chinese medicine research for various diseases, mainly for improving microcirculation in shock state, and can also be used for organophosphate poisoning.

(-)-Asimilobine shows antioxidative, anti-acetylcholinesterase (AChE), anti-α-glucosidase, anti-leishmanial and anti-fungal activities; it displays weak inhibition against Streptococcus mutans (ATCC 25175), with a minimum inhibition concentration (MIC) of 0.25 mg/mL.

Coryneine (Trimethyl(3,4-dihydroxyphenethyl)aminium) is a quaternary ammonium derivative of dopamine derived from aconite root.

Notoginsenosides Fa and R4 show significant neurite outgrowth enhancing activities in human neuroblastoma SK-N-SH cells.