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SLC5A

SLC5A refers to the Solute Carrier Family 5, a group of genes encoding sodium-glucose cotransporters (SGLTs). These integral membrane proteins are crucial for the active transport of glucose and other solutes across cell membranes, particularly in the kidney and intestine. SGLT1 (SLC5A1) and SGLT2 (SLC5A2) are prominent members, playing vital roles in glucose reabsorption and absorption, respectively. Dysregulation of SLC5A transporters is implicated in various metabolic disorders, including diabetes mellitus and glucose-galactose malabsorption.
Catalog No Product Description CAS No. Purity Structural Formula
BP4108
Hydroxy-γ-sanshool
Hydroxy-gamma-sanshool is a fatty amide.
78886-66-5 98% Hydroxy-γ-sanshool
BP4110
Hydroxyl-γ-isosanshool
N-(2-Hydroxyisobutyl)-2,4,8,10,12-tetradecapentaenamide is a fatty amide.
127514-62-9 98% Hydroxyl-γ-isosanshool
BP0150
Aloin B
Aloin B is a C-glycosyl compound that is beta-D-glucopyranose in which the anomeric hydroxy group is replaced by a 4,5-dihydroxy-2-(hydroxymethyl)-10-oxo-9,10-dihydroanthracen-9-yl moiety (the 9R diastereoisomer). It has a role as a metabolite and a laxative. It is a C-glycosyl compound, a member of phenols, a cyclic ketone and a member of anthracenes. Dietary supplementation of aloe components (aloin, aloesin and aloe-gel) can ameliorate intestinal inflammatory responses in a 3% dextran sulfate sodium (DSS)-induced ulcerative colitis rat model, in particular, aloesin is the most potent inhibitor. The extract of A. vera and its active ingredient aloin cause melanin aggregation leading to skin lightening via alpha adrenergic receptor stimulation. Aloin B (Isobalaloin) is an orally active SARS-CoV-2 papain like protease (PLpro) inhibitor with IC50 values of 16.08 (hydrolytic activity) and 17.51 (deubiquitinase activity) μ M. Aloin B can be broken down into aloe emodin 9-anthrone by the gut microbiota of rats to exert its laxative effect. Aloin B can inhibit TPA (HY-18739) - induced ear edema, elevated levels of putrescine, and tumor promoting effects in mouse skin. Aloin B can be used in the research of anti inflammation and inhibition of tumor promotion, novel coronavirus pneumonia (covid-19) and constipation.
28371-16-6 98% Aloin B
BP1807
Auraptene
Auraptene possesses anticarcinogenic, cardioprotective, anti-inflammatory, anti-oxidant, antihelicobacter, antigenotoxic, and neuroprotective effects. Auraptene has a potential to attenuate chronic inflammation in adipose tissue and to improve obesity-related insulin resistance, and has protective effects in transgenic rats developing adenocarcinoma of the prostate (TRAP) and human prostate carcinoma cells. Auraptene is a member of the class of coumarins that is umbelliferone in which the phenolic hydrogen has been replaced by a geranyl group. Ii is isolated from several edible fruits and vegetables and exhibits a variety of therapeutic properties.
495-02-3 98% Auraptene
BP4107 97465-69-5 98% Hydroxy-β-sanshool
BP4990
N-methyltyramine
N-methyltyramine is a member of tyramines. It has a role as a mouse metabolite. It is a conjugate base of a N-methyltyraminium.
370-98-9 98% N-methyltyramine
BP0165
Androsin
Androsin has antiasthmatic effects , it can prevent allergen- and platelet-activating factor (PAF)-induced bronchial obstruction (10 mg/kg orally; 0.5 mg inhalative). Androsin is an active ingredient isolated from Indian Coptis chinensis. Androsin activates the AMPK α/PI3K/Beclin1/LC3 signaling pathway and inhibits the SREBP1c/FASN signaling pathway. Androsin can be used for research on asthma and non-alcoholic fatty liver disease (NAFLD). Androsin has oral activity.
531-28-2 98% Androsin
BP4038
Chrysoobtusin
Chryso-obtusin is a monohydroxyanthraquinone.
70588-06-6 98% Chrysoobtusin