7-Ethyl-10-Hydroxycamptothecin is a member of the class of pyranoindolizinoquinolines that is (4S)-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-dione bearing two additional ethyl substituents at positions 4 and 11 as well as two additional hydroxy substituents at positions 4 and 9. It is the active metabolite of irinotecan and is ~1000 times more active than irinotecan itself. It has a role as an antineoplastic agent, a drug metabolite, an EC 5.99.1.2 (DNA topoisomerase) inhibitor and an apoptosis inducer. 7-Ethyl-10-hydroxycamptothecin shows cytotoxicity against breast cancer, it efficiently target-bind to the colon and lungs of mice.

Costunolide has antipyretic, anti-inflammatory, anti-oxidant, anti-carcinogenic and anti-fungal activities, it possesses normo-glycemic and hypolipidemic activity. Costunolide inhibits RANKL-induced osteoclast differentiation by suppressing RANKL-mediated c-Fos transcriptional activity; it inhibits IL-1beta gene expression by blocking the activation of MAPKs and DNA binding of AP-1; it also induces the ROS-mediated mitochondrial permeability transition and resultant cytochrome c release,. Costunolide is a germacranolide with anthelminthic, antiparasitic and antiviral activities. It has a role as a metabolite, an antiinfective agent, an antiparasitic agent, an anthelminthic drug, an antineoplastic agent and an antiviral drug. It is a heterobicyclic compound and a germacranolide.

Isoschaftoside is a C-glycosyl compound that is apigenin substituted at positions 6 and 8 by alpha-L-arabinopyranosyl and beta-D-glucosyl residues respectively. It has a role as a metabolite. It is a C-glycosyl compound and a trihydroxyflavone. It is functionally related to an apigenin.

Picrocrocin is a beta-D-glucoside of beta-cyclocitral; the precursor of safranal. It is the compound most responsible for the bitter taste of saffron. It is functionally related to a beta-cyclocitral.

Angelicin is a furanocoumarin. Angelicin has anti-cancer, antiviral, and anti-inflammatory activities;it regulates LPS-induced inflammation via inhibiting MAPK/NF-κB pathways. Angelicin is a powerful inducer of erythroid differentiation and -globin mRNA accumulation of human leukemia K562 cells, it is a potential therapeutic approach in hematological disorders, including -beta-thalassemia and sickle cell anemia. ngelicin is a type of furan coumarin NF - κ B and MAPK signaling inhibitor with anti-inflammatory, antiviral, and anti-tumor activities. Angelicin can inhibit the lysis and replication of gamma herpesvirus (such as MHV-68), act in the early stages of viral infection, and may inhibit RTA gene expression (IC50=28.95 μ M). Angelicin also alleviates inflammatory responses by inhibiting NF - κ B phosphorylation and nuclear translocation, as well as inhibiting p38 and JNK phosphorylation. Angelicin downregulates anti apoptotic proteins (such as Bcl-2, Bcl xL, and Mcl-1) and activates caspase-9 and caspase-3 to induce apoptosis in neuroblastoma cells.

Aloe emodin is a dihydroxyanthraquinone that is chrysazin carrying a hydroxymethyl group at position 3. It has been isolated from plant species of the genus Aloe. It has a role as an antineoplastic agent and a plant metabolite. It is an aromatic primary alcohol and a dihydroxyanthraquinone. It is functionally related to a chrysazin. Aloe emodin (Rhabarberone) is a natural hydroxy anthraquinone with anti-tumor activity. Aloe emodin (Rhacarberone) can bind to mTORC2 and inhibit its kinase activity. Aloe emodin (Rhabarberone) exerts anti proliferative effects and induces cell apoptosis. Aloe emodin (Rhabarberone) also exhibits antiviral activity against influenza A virus.

Inulicin is a terpene lactone.

Bruceoside A could be transformed into the potent anticancer component brusatol in vivo, rather than its direct deglycosylated metabolite bruceosin. It significantly inhibited P-388 lymphocytic leukemic cell RNA and protein synthesis in tissue culture.

Eriodictyol has vasodilator, anti-inflammatory and antioxidant activities, it is an antagonist of the transient potential vanilloid 1 receptor (TRPV1) receptor. Eriodictyol may possess antidiabetic properties through increasing glucose uptake and improving insulin resistance, it attenuates the degree of retinal inflammation and plasma lipid peroxidation preserving the blood-retinal barrier (BRB) in early diabetic rats. It may be a potential therapeutic resource for Atopic dermatitis and an adjunctive agent to control itchiness inAtopic dermatitis. (2R)-eriodictoyl-7-O-beta-D-glucopyranosiduronic acid is a beta-D-glucosiduronic acid that is the 7-O-glucuronide of (2R)-eriodictyol. Isolated from the flowers of Chrysanthemum indicum, it exhibits inhibitory activity for rat lens aldose reductase. It has a role as a metabolite and an EC 1.1.1.21 (aldehyde reductase) inhibitor. It is a beta-D-glucosiduronic acid and a 3'-hydroxyflavonoid.

Pelargonidin chloride shows protective effect against CTN-induced oxidative stress in HepG2 cells and up-regulated the activity of detoxification enzyme levels through Keap1/Nrf2 signaling pathway. It also has the antianaphylactic properties, which might be related to the increase of both cyclic AMP and cyclic GMP through the inhibition of phosphodiesterase. Pelargonidin chloride has strong antioxidative activity in a liposomal system and reduced the formation of malondialdehyde by UVB irradiation. Pelargonidin chloride is an anthocyanidin chloride that has pelargonidin as the cationic counterpart. It has a role as a plant metabolite and a phytoestrogen. It contains a pelargonidin.

Morusin is an extended flavonoid that is flavone substituted by hydroxy groups at positions 5, 2' and 4', a prenyl group at position 3 and a 2,2-dimethyl pyran group across positions 7 and 8. It has a role as an antineoplastic agent and a plant metabolite. It is a trihydroxyflavone and an extended flavonoid. Morusin exhibits antinociceptive, analgesic, anticonvulsant, antibacterial, and antitumor activities. Morusin can inhibit NF-κB and STAT3 activity, activate caspases activity, and restorate GABA level.

Pratensein as a novel transcriptional up-regulator of scavenger receptor class B type I in HepG2 cells. Pratensein has anti-inflammatory activity, it has robust activation of acetylcholinesterase expression, the induction of acetylcholinesterase included the levels of mRNA, protein and enzymatic activity; it can significantly ameliorate Aβ1-42-induced spatial learning and memory impairment through reducing neuroinflammation via inhibition of glial activation and NF-κB activation, and restoring synapse and BDNF levels. Pratensein is a member of the class of 7-hydroxyisoflavones in which isoflavone is substituted by hydroxy groups at the 5, 7, and 3' positions, and by a methoxy group at the 4' position. It is a member of 4'-methoxyisoflavones and a member of 7-hydroxyisoflavones. It is a conjugate acid of a pratensein(1-).

After treatment with CVGI, Raffinose family oligosaccharide was hydrolyzed effectively to yield galactose and sucrose. AA-PCD resistance in Raffinose-grown cells occurs with a decrease in both ROS production and cytochrome c release as compared to glucose-grown cells en route to AA-PCD.