Trans-5-O-caffeoyl-D-quinic acid is a cinnamate ester obtained by formal condensation of the carboxy group of trans-caffeic acid with the 5-hydroxy group of quinic acid. It has a role as a plant metabolite. It is a cinnamate ester and a cyclitol carboxylic acid. It is functionally related to a trans-caffeic acid and a (-)-quinic acid. It is a conjugate acid of a trans-5-O-caffeoyl-D-quinate. Neochlorogenic acid shows antioxidant, antibacterial, antiviral, and antipyretic activities and exerts neuroprotective effects through the inhibition of pro-inflammatory pathways in activated microglia. Neochlorogenic acid is a natural polyphenolic compound found in dried fruits and other plants. Neochlorogenic acid inhibits the production of TNF - α and IL-1 β. Neochlorogenic acid inhibits the expression of iNOS and COX-2 proteins. Neochlorogenic acid also inhibits the activation of phosphorylated NF - κ B p65 and p38 MAPK.

Moracin O shows significant neuroprotective, and analgesic activities, it also has a strong protective influence against doxorubicin-induced cardiomyopathy in H9c2 cells with the EC50 value of 4.5 ± 1.3 uM. Moracin O exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1), which is a key mediator during adaptation of cancer cells to tumour hypoxia.

Yadanziolide A shows strong antiviral activity.

Swainsonine is an indolizidine alkaloid isolated from the plant Swainsona canescens with three hydroxy substituents at positions 1, 2 and 8. It has a role as an antineoplastic agent, an immunological adjuvant, an EC 3.2.1.114 (mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase) inhibitor and a plant metabolite.

Icaritin, a potent inhibitor of transcription factor SREBPs, which exhibits a variety of biological activities, such as activation of cancer cell apoptosis and inhibition of growth, hormone regulation, protection against beta amyloid-induced neurotoxicity, and promotion of neuronal and cardiac cellular differentiation. Icaritin shows potent anti-leukemia activity on chronic myeloid leukemia in vitro and in vivo by regulating MAPK/ERK/JNK and JAK2/STAT3 /AKT signalings.

Arnicolide D exerts strong cytotoxic activity on the human colon carcinoma HT-29 cell line.

Khasianine exhibits strong activity against liver damage induced by CCl4.

Palmatrubine binds to double-stranded DNA most probably via an intercalating mode.

Rhodojaponin V is a natural product from Rhododendron molle G. Don.

Cimigenol is a potential antitumor compound, combination of it with an autophagy inhibitor may be a valuable strategy for the chemoprevention or treatment of colon cancer. It exerted potent cytotoxic activity against SMMC-7721 (7.87 µM) and A-549 (12.16 µM). Cimigenol is a triterpenoid. It derives from a hydride of a cycloartane.

Celosin H, celosin I, celosin J could be used as chemical markers for the quality control of C. argentea seeds.

Hellebrigenol shows cytotoxicity against HepG2 cells.

Quassin has female anti-fertility properties, possibly acting via inhibition of estrogen secretion. Quassin alters the immunological patterns of murine macrophages through generation of nitric oxide to exert antileishmanial activity. It also exhibits P. falciparum inhibitory activity (IC50=0.06 micro g/ml, 0.15 micro M). Quassin possesses anti-anaemic property, it can significantly increase red blood cell count, pack cell volume and haemoglobin concentration.

Kansuinine A possesses analgesic props, it also shows NGF inducing activity.