Alismoxide shows an inhibitory effect on the contraction of isolated bladder smooth muscle induced by carbachol; it demonstrates cytostatic action in HeLa cells, revealing potential use in virostatic cocktails. Alismoxide has inhibitory effects on vascular contraction induced by high concentration of KCl; it also shows an inhibitory effect on the direct passive Arthus reaction (DPAR) in rats in the type III allergic model. Alismoxide is a natural compound.

Ginsenoside Rg3 is the main component of Red ginseng, it inhibits Na+ and hKv1.4 channel with IC50s of 32.2±4.5 and 32.6±2.2 μM, respectively, it also inhibits Aβ levels, NF-κB activity, and COX-2 expression. Ginsenoside-Rg3 possesses an ability to inhibit the lung metastasis of tumor cells, and the mechanism of its antimetastatic effect is related to inhibition of the adhesion and invasion of tumor cells, and also to anti-angiogenesis activity. It is a novel drug, capable of inhibiting the early of scarring (HS) and later HS. (20S)-ginsenoside Rg3 is a ginsenoside found in Panax ginseng and Panax japonicus var. major that is dammarane which is substituted by hydroxy groups at the 3beta, 12beta and 20 pro-S positions, in which the hydroxy group at position 3 has been converted to the corresponding beta-D-glucopyranosyl-beta-D-glucopyranoside, and in which a double bond has been introduced at the 24-25 position.

Notoginsenoside Ft1 is a novel stimulator of angiogenesis, it stimulates angiogenesis via HIF-1α-mediated VEGF expression, with PI3K/AKT and Raf/MEK/ERK signaling cascades concurrently participating in the process; it has the potential therapeutic effect on human neuroblastoma, it can arrest the proliferation and elicited the apoptosis of SH-SY5Y cells possibly via p38 MAPK and ERK1/2 pathways.Notoginsenoside Ft1 activates both glucocorticoid and estrogen receptors to induce endothelium-dependent, nitric oxide-mediated relaxations in rat mesenteric arteries. Notoginsenoside Ft1 also provides a great potential application of it in clinics for patients with diabetic foot ulcers, it may accelerate diabetic wound healing by orchestrating multiple processes, including promoting fibroblast proliferation, enhancing angiogenesis, and attenuating inflammatory response.

Chikusetsusaponin IVa is a novel AMPK activator, can induce insulin secretion from βTC3 cells via GPR40 mediated calcium and PKC pathways, may be developed into a new potential for therapeutic agent used in T2DM patients.Chikusetsusaponin IVa exerts antithrombotic effects, including minor hemorrhagic events. Chikusetsusaponin-IVa is a triterpenoid saponin. It has a role as a metabolite.

Alisol A may be an autophagic inducer, it has anti-cancer activity, it presents inhibitory effects on cancer cell lines tested(HepG2, MDA-MB-231, and MCF-7 cells). Alisol A is an orally active terpenoid tetracyclic triterpenoid compound. Alisol A can be extracted from the rhizome of Alisma orientale. Alisol A activates AMPK/ACC/SREBP-1c, SIRT1, PPAR α, inhibits MMP-2/-9, and reduces the expression of inflammatory cytokines (IL-1 β, IL-6, IL-8). Alisol A has antitumor activity against breast cancer and colorectal cancer. Alisol A has anti obesity and anti atherosclerosis activities. Alisol A can be used to study hepatitis B, breast cancer, colorectal cancer, atherosclerosis and obesity.

artemisinin is a sesquiterpene lactone obtained from sweet wormwood, Artemisia annua, which is used as an antimalarial for the treatment of multi-drug resistant strains of falciparum malaria. It has a role as an antimalarial and a plant metabolite. It is an organic peroxide and a sesquiterpene lactone. Artemisinin is a sesquiterpene endoperoxide which is a potent antimalarial agent. Artemisinin is active against different bacteria and certain fungal species. It inhibits tumor necrosis factor-α-induced vascular smooth muscle cell proliferation. Artemisinin (Qinghaosu) is a sesquiterpene lactone, an anti malarial active molecule isolated from the aboveground parts of Artemisia annua L. plants. Artemisinin reduces pAKT in a dose-dependent manner to inhibit the AKT signaling pathway. Artemisinin can reduce the proliferation, migration, invasion, tumorigenesis, and metastasis of cancer cells, while also having neuroprotective effects.

Alpha Typerone is associated with downregulation of Cox-2, IL-6, Nck-2, Cdc42, and Rac1 expression, thereby reducing inflammatory response.

Ajugasterone C is a steroid. Ajugasterone C shows significant inhibitory effect at 100 mg/kg dose on rat paw oedema development due to carrageenan-induced inflammation in Sprague Dawley rats. Ajugasterone C is a degenerate steroid isolated from Leuzea carthamoids.

(±)-Borneol is a bornane monoterpenoid that is 1,7,7-trimethylbicyclo[2.2.1]heptane substituted by a hydroxy group at position 2. It has a role as a metabolite and a volatile oil component.(±)-Borneol is a bornane monoterpenoid that is 1,7,7-trimethylbicyclo[2.2.1]heptane substituted by a hydroxy group at position 2. It has a role as a metabolite and a volatile oil component. (±)-Borneol is a bicyclic monoterpene used for analgesia and anaesthesia in traditional Chinese and Japanese medicine, it and its enantiomer (±)-Borneol have a highly efficacious positive modulating action at GABA(A) receptors at human recombinant alpha1beta2gamma2L GABA(A) receptors. Borneol specifically inhibits the nicotinic acetylcholine receptor (nAChR)-mediated effects in a noncompetitive way, can depress P-glycoprotein function by a NF-κB signaling mediated mechanism in a blood brain barrier in vitro model. Borneol has neuroprotection through the inhibition of IκBα-NF-κB and translocation signaling pathway, it also has an anti-cerebral ischemia effects. It can suppresse inflammatory responses in LPS-induced acute lung injury through inhibition of the NF-κB and MAPKs signaling pathways.

Deoxycholic acid is a strong promoter of hepatocarcinogenesis with possible complete carcinogenicity in the liver and promotion potential for tumor development in the small intestine. Loss of deoxycholic acid-induced EGFR/Ras/MAPK pathway function potentiates deoxycholic acid-stimulated FAS-induced hepatocyte cell death via a reduction in the expression of c-FLIP isoforms. Deoxycholic acid is a bile acid that is 5beta-cholan-24-oic acid substituted by hydroxy groups at positions 3 and 12 respectively. It has a role as a human blood serum metabolite. It is a C24-steroid, a dihydroxy-5beta-cholanic acid and a bile acid. It is a conjugate acid of a deoxycholate.

Chenodeoxycholic acid is a dihydroxy-5beta-cholanic acid that is (5beta)-cholan-24-oic acid substituted by hydroxy groups at positions 3 and 7 respectively. It has a role as a mouse metabolite and a human metabolite. It is a C24-steroid, a dihydroxy-5beta-cholanic acid and a bile acid. It is a conjugate acid of a chenodeoxycholate. Chenodeoxycholic acid is a hydrophobic primary bile acid that activates nuclear receptors (FXR) involved in cholesterol metabolism. Chenodeoxycholic acid could reverse obesity in cHF-fed mice, mainly in response to the reduction in food intake.

Oleanonic acid is an orally administered triterpenoid with anti-inflammatory and insect resistant activities. Oleanonic acid can improve oxidative stress, autophagy deficiency, iron death, mitochondrial damage, and endoplasmic reticulum stress induced by amyloid - β precursor protein in vitro, and improve myocardial hypertrophy in rats in vivo.