Gossypol is an effective natural antimicrobial agent against a wide range of potential fungal pathogens of cotton.Gossypol shows a significant increase in accumulation of acidic vesicular organelle, is a promising drug that induces autophagic cell death in radioresistant malignant glioma.Gossypol binds to Bcl-xL protein and Bcl-2 protein with Kis of 0.5-0.6 μM and 0.2-0.3 mM, respectively. Gossypol is an aldehyde, a hydroxynaphthalene, a polyphenol and a hexol. It has a role as an antispermatogenic agent, an anti-inflammatory agent and a plant metabolite.

Prunetin is a hydroxyisoflavone that is genistein in which the hydroxy group at position 7 is replaced by a methoxy group. It has a role as a metabolite, an EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor, an EC 1.3.1.22 [3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))] inhibitor and an anti-inflammatory agent. It is a member of 7-methoxyisoflavones and a hydroxyisoflavone. It is functionally related to a genistein. It is a conjugate acid of a prunetin-5-olate. Prunetin mediates anti-obesity/adipogenesis effects by suppressing obesity-related transcription through a feedback mechanism that regulates the expression of adiponectin, adipoR1, adipoR2, and AMPK. Prunetin and biochanin A are potent reducers of NF-κB and ERK activation, zonula occludens 1 tyrosine phosphorylation, and metalloproteinase-mediated shedding activity, which may account for the barrier-improving ability of these isoflavones.

L-arginine is an L-alpha-amino acid that is the L-isomer of arginine. It has a role as a micronutrient, a nutraceutical, a biomarker, a mouse metabolite and an Escherichia coli metabolite. It is a L-alpha-amino acid, a glutamine family amino acid, an arginine and a proteinogenic amino acid. It is a conjugate base of a L-argininium(1+). It is a conjugate acid of a L-argininate. It is an enantiomer of a D-arginine. L-Arginine is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis. L-Arginine exhibits anti-atherosclerotic effect, L-arginine and soy enriched diet are effective in prevention of osteoporosis associated with diabetes mellitus. Exogenous L-Arginine could enhance neonate lymphocyte proliferation through an interleukin-2-independent pathway.

Protogracillin may have inhibitions on platelet aggregation (PAG) and thrombosis.

Thevetiaflavone ameliorates PC12 cells injury induced by OGD/R via improving ROS‑mediated mitochondrial dysfunction, it can upregulate the expression of Bcl‑2 and downregulate that of Bax and caspase‑3.

Danshenxinkun A, Danshenxinkun B and Neocryptotanshinone may intervene thrombotic diseases by adjusting the targets mainly involved in pathways of endocrine system, signal transduction, signaling molecules and interaction, cell motility, environmental adaptation and nervous system. Oleoyl danshenxinkun A also selectively inhibits rabbit platelet aggregation induced by arachidonic acid.

Albiflorin is a monoterpene glycoside with formula C23H28O11, originally isolated from the roots of Paeonia lactiflora. It has a role as a neuroprotective agent and a plant metabolite. It is a beta-D-glucoside, a secondary alcohol, a bridged compound, a benzoate ester, a gamma-lactone and a monoterpene glycoside. Albiflorin has anti-inflammatory, and antidepressant-like effects. Albiflorin may reduce or prevent osteoblast degeneration in osteoporosis, and may promote the recovery of bone marrow hemopoietic function in a myelosuppressed mouse model, it has neuroprotective effect on primary hippocampal cells against β-amyloid induced toxicity. Albiflorin is a monoterpene glycoside with neuroprotective effects that can cross the blood-brain barrier. It also exhibits anti-inflammatory, antioxidant, and analgesic properties.

Pulsatilla saponin D exhibits anticancer activities in various cancer types, it Inhibits autophagic flux and synergistically enhances the anticancer activity of chemotherapeutic agents against HeLa cells.Pulsatilla saponin D has strong haemolytic activity. Pulsatilla saponin D is a natural product found particularly in Pulsatilla chinensis and Pulsatilla cernua. It has a role as a metabolite.

1,5-Dicaffeoylquinic acid is a derivative of caffeoylquinic acid, which possesses antioxidant activity and free radical scavenging activity.

Tribuloside has 1,1-diphenyl-2-picrylhydrazyl radical scavenging activity, it can improve behavior and BrdU immunoreactive cells of depression model rats and possess antidepressant effect. Tribuloside exhibits antimycobacterial activity against the non-pathogenic Mycobacterium species Mycobacterium madagascariense and Mycobacterium indicus pranii, with a minimum inhibitory concentration (MIC) 5.0 mg/mL. Tribuloside is a glycosyloxyflavone that is kaempferol attached to a 6-O-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-beta-D-glucopyranosyl residue at position 3 via a glycosidic linkage. It has a role as a plant metabolite. It is a trihydroxyflavone, a cinnamate ester, a glycosyloxyflavone and a monosaccharide derivative. It is functionally related to a kaempferol and a trans-4-coumaric acid.

Beta-benzoyloxypaeoniflorin is a monoterpene glycoside with formula C30H32O13, isolated from several species of Paeoniae. It has a role as a platelet aggregation inhibitor, an EC 1.14.18.1 (tyrosinase) inhibitor and a plant metabolite. It is a beta-D-glucoside, a bridged compound, a lactol, an O-acyl carbohydrate, a cyclic acetal, a monoterpene glycoside and a 4-hydroxybenzoate ester.

Monoxerutin is a glycoside and a member of flavonoids.

1,3-Dicaffeoylquinic acid is a derivative of caffeoylquinic acid, which possesses antioxidant activity and free radical scavenging activity.

Przewaquinone A has antitumor activity.

3-hydroxy-4-methoxybenzoic acid is a methoxybenzoic acid that is 4-methoxybenzoic acid bearing a hydroxy substituent at position 3. It has a role as an antibacterial agent and a plant metabolite. It is a methoxybenzoic acid and a monohydroxybenzoic acid. It is a conjugate acid of a 3-hydroxy-4-methoxybenzoate. Isovanillic acid shows distinct anti -inflammatory activities with no toxicity on RAW 264.7 macrophage cells.

alpha-thujone is the (1S,4R,5R)-stereoisomer of alpha-thujone. It is an enantiomer of a (+)-alpha-thujone.

Aromadendrin 7-O-glucoside is a glycoside and a member of flavonoids. Sinensin is a natural product from Cudrania cochinchinensis.

Mulberrofuran Q is a member of benzofurans.