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ALOX15

Catalog No Product Description CAS No. Purity Structural Formula
BP0135
Alismoxide
Alismoxide shows an inhibitory effect on the contraction of isolated bladder smooth muscle induced by carbachol; it demonstrates cytostatic action in HeLa cells, revealing potential use in virostatic cocktails. Alismoxide has inhibitory effects on vascular contraction induced by high concentration of KCl; it also shows an inhibitory effect on the direct passive Arthus reaction (DPAR) in rats in the type III allergic model. Alismoxide is a natural compound.
87701-68-6 98% Alismoxide
BP4150
Arachidonic acid
Arachidonic acid is 1 of only 2 unsaturated fatty acids retained in the ovaries of crustaceans and an inhibitor of HR97g, a nuclear receptor expressed in adult ovaries. Arachidonic acid induces retinal arteriolar vasodilation by inhibiting subcellular Ca(2+)-signaling activity in retinal arteriolar myocytes, most likely through a mechanism involving the inhibition of L-type Ca(2+)-channel activity. Arachidonic acid causes an increase in free cytoplasmic calcium concentration ([Ca2+]i) in differentiated skeletal multinucleated myotubes C2C12 and does not induce calcium response in C2C12 myoblasts. Arachidonic acid is a long-chain fatty acid that is a C20, polyunsaturated fatty acid having four (Z)-double bonds at positions 5, 8, 11 and 14. It has a role as a mouse metabolite, a human metabolite, an EC 3.1.1.1 (carboxylesterase) inhibitor and a Daphnia galeata metabolite. It is a long-chain fatty acid, an omega-6 fatty acid and an icosa-5,8,11,14-tetraenoic acid. It is a conjugate acid of an arachidonate. It derives from a hydride of a (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraene.
506-32-1 99% Arachidonic acid
BP0146
Aloe emodin
Aloe emodin is a dihydroxyanthraquinone that is chrysazin carrying a hydroxymethyl group at position 3. It has been isolated from plant species of the genus Aloe. It has a role as an antineoplastic agent and a plant metabolite. It is an aromatic primary alcohol and a dihydroxyanthraquinone. It is functionally related to a chrysazin. Aloe emodin (Rhabarberone) is a natural hydroxy anthraquinone with anti-tumor activity. Aloe emodin (Rhacarberone) can bind to mTORC2 and inhibit its kinase activity. Aloe emodin (Rhabarberone) exerts anti proliferative effects and induces cell apoptosis. Aloe emodin (Rhabarberone) also exhibits antiviral activity against influenza A virus.
481-72-1 98% Aloe emodin
BP4720
Decaffeoylacteoside
Verbasoside is a glycoside.
61548-34-3 98% Decaffeoylacteoside
BP0153
Alpha-Boswellic acid
Alpha-Boswellic acid is a triterpenoid. alpha-Boswellic acid (α-BA)has gastroprotective properties by decreasing oxidative stress and the Nrf2/HO-1 pathway. α-BA also has protective effects against acetaminophen (APAP)-induced hepatotoxicity in Balb/ cA mice.α-BA could be considered as a potent therapeutic agent for prevention and decreasing the progression of Alzheimer’s hallmarks, it can efficiently reduce hyperphosphorylated Tau (Ser404) in STZ-treated astrocytes and decrease ROS generation and promote proliferation of astrocytes through elevating Survivin expression. Alpha Boswellic acid is a pentacyclic triterpenoid compound with oral activity that can be extracted from frankincense. Alpha Boswellic acid has anti-inflammatory and anti-tumor activities. Alpha Boswellic acid can be used for research on Alzheimer's disease (AD).
471-66-9 98% Alpha-Boswellic acid
SBP00049
Benzoic acid
Benzoic acid is a compound comprising a benzene ring core carrying a carboxylic acid substituent. It has a role as an EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor, an EC 3.1.1.3 (triacylglycerol lipase) inhibitor, an antimicrobial food preservative, a plant metabolite, a human xenobiotic metabolite, an algal metabolite and a drug allergen. It is a conjugate acid of a benzoate. Benzoic acid is a colorless crystalline solid and a simple aromatic carboxylic acid, used as a food preservative. Benzoic acid can improve feed efficiency and diarrhoea, and improve gut microfloral composition.
65-85-0 98% Benzoic acid
BP5085 477-83-8 98% Damnacanthol
BP3085 130783-32-3 98% Benzoylgomisin O
BP0055
3,4-Dicaffeoylquinic acid
3,4-Dicaffeoylquinic acid is a conjugate acid of a 4,5-di-O-caffeoyl quinate. 3,4-Dicaffeoylquinic acid is naturally isolated and has antioxidant, DNA protective, neuroprotective, and hepatoprotective properties. 3,4-Dicaffeoylquinic acid exhibits apoptosis mediated cytotoxicity and alpha glucosidase inhibition. 3,4-Dicaffeoylquinic acid has a unique antiviral mechanism by increasing TRAIL to enhance virus clearance.
14534-61-3 98% 3,4-Dicaffeoylquinic acid
BP0106
8-Desoxygartanin
8-Desoxygartanin is a member of xanthones.
33390-41-9 98% 8-Desoxygartanin
BP0235
Bakuchiol
Bakuchiol possesses anti-tumor, cytotoxic, anti-bacterial , and anti-helmenthic properties, it shows DNA polymerase1 inhibiting activity. Bakuchiol has great potential for use in food additives and mouthwash for preventing and treating dental caries.
10309-37-2 98% Bakuchiol
BP0006
Cynarine
1,5-Dicaffeoylquinic acid is a derivative of caffeoylquinic acid, which possesses antioxidant activity and free radical scavenging activity.
30964-13-7 98% Cynarine
BP0005
1,3-Dicaffeoylquinic acid
1,3-Dicaffeoylquinic acid is a derivative of caffeoylquinic acid, which possesses antioxidant activity and free radical scavenging activity.
19870-46-3 98% 1,3-Dicaffeoylquinic acid
BP0158
Alpha-Terpineol
Alpha-terpineol is a terpineol that is propan-2-ol substituted by a 4-methylcyclohex-3-en-1-yl group at position 2. It has a role as a plant metabolite. Alpha-Terpineol has antitumour, anti-inflammatory, and antimicrobial activities, it inhibits the growth of tumour cells through a mechanism that involves inhibition of the NF-kappaB pathway; it can suppress the production of inflammatory mediators in LPS-stimulated human macrophages by interfering with the NF-kB, p38 or ERK MAPK pathways. Alpha-Terpineol may have utility as an anti-MRSA cleansing agent for dental instruments and dental unit chairs. Alpha Terpineol can be found in Eucalyptus globulus Labill and has oral activity. Alpha Terpineol has strong antibacterial activity against periodontal disease and cariogenic bacteria. In addition, α - Terpineol also has antifungal activity (T. mentagrophytes), which may lead to irreversible cell division. Meanwhile, α - Terpineol has anti neuropathic and anti-inflammatory activities. Alpha Terpineol can be used for research in areas such as diarrhea, neuropathic pain, infection, inflammation, metabolism, etc.
98-55-5 98% Alpha-Terpineol
BP0096
Isomucronulatol
Isomucronulatol is an ether and a member of flavonoids. Isomucronulatol is a flavonoid compound isolated from the roots of A. membranaceus. Isomucronulatol has inhibitory effects on IL-12 p40 stimulated by LPS in vitro and has potential anti-inflammatory activity.
64474-51-7 98% Isomucronulatol
BP0176
Anwuligan
Anwuligan is a natural active ingredient extracted from plants such as Schisandra chinensis. It belongs to the lignan class of compounds and has antioxidant, anti-inflammatory, and metabolic regulating effects. Current research shows that it may have auxiliary improvement effects on liver dysfunction, chemical liver injury, and other conditions.
107534-93-0 98% Anwuligan
BP0144
Alloimperatorin
Alloimperatorin is a member of psoralens. Alloimperatorin exhibits in vitro antitumor activity in HL-60 acute myeloid leukemia cancer cells via inducing apoptosis, cell cycle disruption and inhibition of cell migration. It photosensitizes efficiently the hemolysis of erythrocytes. Alloimperatorin (Prangenidin), A coumarin compound extracted from Angelica dahurica. Alloimpactorin (Prangenidin) has anti-tumor activity.
642-05-7 98% Alloimperatorin
BP0149
Aloin A
Aloin A is a C-glycosyl compound that is beta-D-glucopyranose in which the anomeric hydroxy group is replaced by a 4,5-dihydroxy-2-(hydroxymethyl)-10-oxo-9,10-dihydroanthracen-9-yl moiety (the 9S diastereoisomer). It has a role as a metabolite and a laxative. It is a C-glycosyl compound, a member of phenols, a cyclic ketone and a member of anthracenes. Aloe components (aloin, aloesin and aloe-gel) show anti-inflammatory effects, they can ameliorate intestinal inflammatory responses in a dextran sulfate sodium (DSS)-induced ulcerative colitis rat model. Aloin shows tyrosinase activity, it could be used as lightening agents in the treatment of hyperpigmentation disorders and cosmetic additives. Aloin is a potent proapoptotic agent, it showed a pronounced antiproliferative effect at physiological concentration (IC50 = 97 microM), caused cell cycle arrest in the S phase and markedly increased HeLaS3 cell apoptosis (to 24%). Aloin (Aloin-A; Barbaloin-A) is a natural anti-tumor anthraquinone glycoside with iron chelation activity. Aloin induces differentiation of MC3T3-E1 cells into osteoblasts through the MAPK mediated Wnt and Bmp signaling pathways. Alkaline phosphatase (ALP) is an early marker of osteoblast differentiation, and its activity is also enhanced by Aloin. Aloin can alleviate brain edema, reduce blood-brain barrier damage, and improve cortical shock injury. Aloin can be used for research on osteoporosis and traumatic brain injury (TBI).
1415-73-2 98% Aloin A
BP0003
Demethylbellidifolin
Bellidin is a member of the class of xanthones that is xanthone which is substituted by hydroxy groups at positions 1, 3, 5, and 8. A natural product found particularly in Iris nigricans and Gentiana campestris. It has a role as an antioxidant, a metabolite, a mutagen, an EC 3.1.1.7 (acetylcholinesterase) inhibitor and a radical scavenger. It is a tetrol and a member of xanthones. It is functionally related to a xanthone.
2980-32-7 98% Demethylbellidifolin
BP0056
3,5-Dicaffeoylquinic acid
3,5-Dicaffeoylquinic acid is a carboxylic ester that is the diester obtained by the condensation of the hydroxy groups at positions 3 and 5 of ()-quinic acid with the carboxy group of trans-caffeic acid. Isolated from Brazilian propolis and Suaeda glauca, it exhibits hepatoprotective and cytotoxic activities. It has a role as a metabolite, an antineoplastic agent and a hepatoprotective agent. It is a carboxylic ester and a cyclitol carboxylic acid. 3,5-Dicaffeoylquinic acid is a natural phenolic acid with antimutagenic, anti hepatitis B virus, anti HIV, antioxidant, antibacterial and anti-inflammatory activities.
2450-53-5 98% 3,5-Dicaffeoylquinic acid