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IDO1

Catalog No Product Description CAS No. Purity Structural Formula
BP3545
Kushenol E
Kushenol E exhibits significant antioxidant potentials in the ABTS, ONOO(-), and total ROS assays.
99119-72-9 98% Kushenol E
BP0002 116064-77-8 98% 1,2-Didehydromiltirone
BP3276
Octahydrocurcumin
Octahydrocurcumin has antioxidant and and anti-inflammatory activities, it can inhibit the lipopolysaccharide (LPS)-induced inflammatory response via the mechanism of inhibiting NF-κB translocation to the nucleus. Octahydrocurcumin exhibits potent cytotoxic effect (IC50 =19.46 ug/mL) and shows high antimicrobial activity.
36062-07-4 98% Octahydrocurcumin
BP0061
3-Butylidenephthalide
3-Butylidenephthalide is an isobenzofuranone. 3-Butylidenephthalide has antihyperglycemic effect is due to inhibition of α-glucosidase at the intestinal level, inhibited the activity of yeast-α-glucosidase (IC(50) 2.35 mM) in a noncompetitive fashion with a K(i) of 4.86 mM. It can induce a dose-dependent antinociceptive action in the hot-plate assay, it is also effective for controlling the pain provoked by chemical irritation at the doses of 10 and 31.6 mg/kg. 3-Butylidenephthalide is a phthalic anhydride derivative identified from Ligusticum chuanxiong Hort, with insecticidal activity (LC50 value of 1.56 mg/g for Spodoptera litura larvae).
551-08-6 98% 3-Butylidenephthalide
BP1399
Topotecan Hydrochloride
Topotecan hydrochloride, a topoisomerase I inhibitor, capable of inhibiting tumoral growth in animal models of retinoblastoma. Topotecan hydrochloride liposomes loaded CS/β-GP hydrogel could become a potential formulation for improving the antitumor efficacy of Topotecan hydrochloride. Topotecan hydrochloride is a pyranoindolizinoquinoline. It has a role as an antineoplastic agent and an EC 5.99.1.2 (DNA topoisomerase) inhibitor. It contains a topotecan.
119413-54-6 98% Topotecan Hydrochloride
BP1229
Rubitecan
Rubitecan is a pyranoindolizinoquinoline that is camptothecin in which the hydrogen at position 9 has been replaced by a nitro group. It is a prodrug for 9-aminocamptothecin. It has a role as an antineoplastic agent, a prodrug and an EC 5.99.1.2 (DNA topoisomerase) inhibitor. It is a delta-lactone, a tertiary alcohol, a C-nitro compound, a pyranoindolizinoquinoline and a semisynthetic derivative. Rubitecan is a novel oral inhibitor of topoisomerase I in the camptothecin class. It shows antitumour activity in patients with refractory pancreatic cancer who have failed prior treatments.
91421-42-0 98% Rubitecan
BP1629
3,6′-Disinapoylsucrose.
3',6-Disinapoyl sucrose is a hydroxycinnamic acid.
139891-98-8 98% 3,6′-Disinapoylsucrose.
BP0390
Coptisine
Coptisine is an efficient uncompetitive IDO inhibitor with a Ki value of 5.8 μM and an IC50 value of 6.3 μM, it can consequently prevent neuron loss, reduce amyloid plaque formation, and ameliorate impaired cognition, it could as a potential new class of drugs for AD treatment. Coptisine has cardioprotection, anti- hypercholesterolemia, anti-fungal, anti-osteosarcoma, anti-hepatoma and anti-leukaemia activities, it also has antispasmodic and relaxant activity on a guinea-pig ileum. Coptisine is a natural product found in Coptis japonica. It has a role as a metabolite.
3486-66-6 98% Coptisine
BPF2740
Dehydroeburicoic acid
Dehydroeburicoic acid induces necrotic cell death that involves Ca(2+) overload, mitochondrial dysfunction, and calpain activation in human glioblastomas. Dehydroeburicoic acid and Eburicoic acid have antioxidant and anti-inflammatory activities by the decrease of inflammatory cytokines and an increase of antioxidant enzyme activity, can protect the liver from CCl4-induced hepatic damage.
6879-05-6 98% Dehydroeburicoic acid
BP1828 18286-71-0 98% Macamide Impurity 3
BP1829 883715-22-8 98% Macamide Impurity 10
BP3263
Naringenin-7-O-β-D-glucoside
Naringenin 7-O-beta-D-glucoside is a flavanone 7-O-beta-D-glucoside that is (S)-naringenin substituted by a beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage. It has a role as a metabolite, an antibacterial agent, a hypoglycemic agent and an antilipemic drug. It is a flavanone 7-O-beta-D-glucoside, a member of 4'-hydroxyflavanones, a (2S)-flavan-4-one, a dihydroxyflavanone and a monosaccharide derivative. It is functionally related to a (S)-naringenin.
529-55-5 98% Naringenin-7-O-β-D-glucoside
BP5321
Sibiricose A1
The sibiricosee A1, the sibiricose A5 and the tenuifoliside A have a better treatment function for tristimania caused by various reasons the sibiricose A5 and the tenuifoliside A have a certain protecting function for PC 12 cells damaged by glutamic acid and the sibiricosee A1, the sibiricose A5 and the tenuifoliside A all can shorten the tail-hanging resting time and the swim resting time of a mouse.
139726-40-2 98% Sibiricose A1
BP0391
Coptisine Chloride
Coptisine is an isoquinoline alkaloid isolated from Coptidis Rhizoma with anti-diabetic, antimicrobial, antiviral, anti-hepatoma, and anti-leukemia effects. Coptisine protects rat heart against myocardial ischemia/reperfusion injury by suppressing myocardial apoptosis and inflammation. Coptisine chloride can be absorbed across intestinal epithelial cells, and completely absorbed compounds.
6020-18-4 98% Coptisine Chloride
BP1554 80952-72-3 98% 20(R)-Ginsenoside Rg2
BP3281
Officinalisinin I
Officinalisinin Ⅰcan effectively reduce the blood glucose and protect nerve injuryin diabetic mice.
57944-18-0 98% Officinalisinin I
BP4896
Entadamide A
Entadamide A is a N-acylethanolamine.
100477-88-1 98% Entadamide A
BP3044
7,8-Dihydroxy-4-methylcoumarin
7,8-dihydroxy-4-methyl-1-benzopyran-2-one is a hydroxycoumarin.
2107-77-9 98% 7,8-Dihydroxy-4-methylcoumarin
SBP04101 5989-02-6 Loliolide
BP4440 135432-48-3 98% Liquiritigenin-7-O-apiosyl(1-2)-glucoside