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NOTCH1

Catalog No Product Description CAS No. Purity Structural Formula
BP0001
1,2,3,4,6-Pentagalloylglucose
1,2,3,4,6-pentakis-O-galloyl-beta-D-glucose is a galloyl-beta-D-glucose compound having five galloyl groups in the 1-, 2-, 3-, 4- and 6-positions. It has a role as a geroprotector, an antineoplastic agent, a radical scavenger, a hepatoprotective agent, a radiation protective agent, an anti-inflammatory agent and a plant metabolite. It is a galloyl beta-D-glucose and a gallate ester. It is a conjugate acid of a 1,2,3,4,6-pentakis-O-galloyl-beta-D-glucose(1-).
14937-32-7 98% 1,2,3,4,6-Pentagalloylglucose
BP0146
Aloe emodin
Aloe emodin is a dihydroxyanthraquinone that is chrysazin carrying a hydroxymethyl group at position 3. It has been isolated from plant species of the genus Aloe. It has a role as an antineoplastic agent and a plant metabolite. It is an aromatic primary alcohol and a dihydroxyanthraquinone. It is functionally related to a chrysazin. Aloe emodin (Rhabarberone) is a natural hydroxy anthraquinone with anti-tumor activity. Aloe emodin (Rhacarberone) can bind to mTORC2 and inhibit its kinase activity. Aloe emodin (Rhabarberone) exerts anti proliferative effects and induces cell apoptosis. Aloe emodin (Rhabarberone) also exhibits antiviral activity against influenza A virus.
481-72-1 98% Aloe emodin
BP0319
Carvacrol
Carvacrol is a phenol that is a natural monoterpene derivative of cymene. An inhibitor of bacterial growth, it is used as a food additive. Potent activator of the human ion channels transient receptor potential V3 (TRPV3) and A1 (TRPA1). It has a role as a TRPA1 channel agonist, a volatile oil component, an antimicrobial agent, an agrochemical and a flavouring agent. It is a p-menthane monoterpenoid, a member of phenols and a botanical anti-fungal agent. It derives from a hydride of a p-cymene.
499-75-2 98% Carvacrol
BP0163 486-89-5 Anagyrine
BP0712
Helenine
Alantolactone is a sesquiterpene lactone that is 3a,5,6,7,8,8a,9,9a-octahydronaphtho[2,3-b]furan-2-one bearing two methyl substituents at positions 5 and 8a as well as a methylidene substituent at position 3. It has a role as an antineoplastic agent, an apoptosis inducer and a plant metabolite. It is a sesquiterpene lactone, a naphthofuran and an olefinic compound.
546-43-0 98% Helenine
BP0891
Lucidin
Lucidin and its derivatives are genotoxic, it is mutagenic at the hypoxanthine-guanine phosphoribosyl transferase gene locus.
478-08-0 98% Lucidin
SBP02731 136685-37-5 9-Deoxygoniopypyrone
BP0830
Khasianine
Khasianine exhibits strong activity against liver damage induced by CCl4.
32449-98-2 98% Khasianine
BP1066
Parthenolide
Parthenolide exhibits anti-cancer, anti-inflammatory, immunomodulatory, anti-Leishmania, and antimigraine effects, it inhibits nociception and neurogenic vasodilatation in the trigeminovascular system by targeting the TRPA1 channel.Parthenolide is also an inhibitor of the nuclear factor-kappaB pathway, can ameliorate cardiovascular derangement and outcome in endotoxic shock in rodents. (1Ar,7aS,10aS,10bS)-1a,5-dimethyl-8-methylidene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one is a germacranolide.
20554-84-1 98% Parthenolide
BP0169
Anemoside A3
Pulchinenoside A3 is a triterpenoid. Anemoside A3 is an attractive candidate for further development as a cognitive enhancer capable of alleviating memory dysfunctions associated with aging and neurodegenerative diseases. Anemoside A3 also produces relaxation in rat renal arteries through multiple mechanisms.
129724-84-1 98% Anemoside A3
BP5308
Forbesione
Forbesione exhibits anti-HIV-1 activity. Forbesione also has antitumor effects, it combined with 5-FU strongly induced apoptosis in Ham-1 cells.
180961-63-1 98% Forbesione
BP0008
1,8-Dihydroxyanthraquinone
Chrysazin is a dihydroxyanthraquinone that is anthracene-9,10-dione substituted by hydroxy groups at positions 1 and 8. It has a role as an apoptosis inducer and a plant metabolite.
117-10-2 98% 1,8-Dihydroxyanthraquinone
BP0156
Alpha-Solanine
Alpha-Solanine is a glycoalkaloid poison found in species of the nightshade family (Solanaceae), such as the potato (Solanum tuberosum). It is a trisccharide derivative of solanidine [(22beta)-solanid-5-en-3beta-ol]. It has a role as an antineoplastic agent, a phytotoxin, an apoptosis inducer and a plant metabolite. It is a glycoalkaloid, an organic heterohexacyclic compound, a steroid saponin and a trisaccharide derivative. It is functionally related to a solanidine. Alpha-Solanine alters antioxidative enzyme activities and MDA and PCO concentrations and GST activity in fat body and midgut. Alpha-Solanine has proliferation-inhibiting and apoptosis-promoting effect on multiple cancer cells, such as clone, liver, melanoma cancer cells.
20562-02-1 98% Alpha-Solanine
BP4377 62287-47-2 98% Neoanhydropodophyllol
BP4206
Macrozamin
Macrozamin has carcinogenic, mutagenic, teratogenic and neurotoxic properties.
6327-93-1 98% Macrozamin
BP0042 112246-15-8 98% 20(R)-Ginsenoside Rh2
BP1360
Tangeretin
Tangeretin is a Notch-1 inhibitor, has antiproliferative, antiinvasive, antimetastatic and antioxidant activities.Tangeretin has therapeutic potential for melanoma and melanoma-associated depigmentation, because it can induce hyperpigmentation through the activation of melanogenic signaling proteins and initiation of sustained ERK2 expression. Tangeretin is a pentamethoxyflavone flavone with methoxy groups at positions 4', 5, 6 , 7 and 8. It has a role as an antineoplastic agent and a plant metabolite.
481-53-8 98% Tangeretin