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Product name: Ergothionine
Synonym name: L-(+)-Ergothioneine; Ergothioneine；Phytothioneine；Sympectothion
Catalogue No.: BP4513
Cas No.: 497-30-3
Formula: C9H15N3O2S
Mol Weight: 229.298
Botanical Source:
Type of Compound:
Purity: 99%
Analysis Method: HPLC-DAD or/and HPLC-ELSD
Identification Method: Mass, NMR
Packing: Brown vial or HDPE plastic bottle
The product could be supplied from milligrams to grams, up to kilograms.
Inquire for bulk scale.
L-Ergothioneine is a stable antioxidant that can be found under conditions of excessive oxidative stress in plant and animal tissue. L-ergothioneine has the ability to scavenge free radicals and protect cells from UV-induced ROS with higher efficiency than antioxidants coenzyme Q(10) or idebenone, thus making it more effective antioxidant. The compound has been shown to be a non-toxic thiol buffering antioxidant, enhance cell viability induced by hydrogen peroxide (H2O2), and inhibit DNA oxidation by peroxynitrite (ONOO-) in the human neuronal hybridoma cell line (N-18-RE-105).
L-(+)-Ergothioneine is a naturally-occurring amino acid derived from histidine via hercynine.1 Ergothioneine is a stable antioxidant that scavenges and detoxifies free radicals and oxidants, increases intracellular thiol levels, controls nuclear factor-κB activation, and inhibits inflammatory gene expression.In addition, it inhibits the peroxynitrite-dependent nitration of nitrotyrosine, blocks oxidative DNA damage and cell death, and prevents the formation of xanthine and hypoxanthine. Ergothioneine is transported by the organic cation/carnitine transporter, which has been linked with autoimmune diseases, including rheumatoid arthritis and Crohn’s disease.
HNMR of Ergothionine
HPLC of Ergothionine
Storage conditions：Short-term storage at 2~8℃, long-term storage at -20 ~ -80℃
71.7100
-2.4476
-2.4476
.4028
.5437
.7661
Low
37.1892
4.5085
Yes
Yes
No
No
No
No
0.3
No
Yes
No
No
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