6-Methoxydihydrosanguinarine

Name: 6-Methoxydihydrosanguinarine
Brand: Phytopurify
Rating: 5 (1 reviews)

Catalogue No.： BP2131

CAS NO.: 72401-54-8

Purity: 98%

Brand: Phytopurify

Botanical Source:

6-Methoxydihydrosanguinarine may have anti-inflammatory effects via the inhibition of NO and IL-6 expression through the down-regulation of MAP kinase (ERK1/2, p38) phosphorylation in RAW 264.7 cells. It has antibacterial activity against Methicillin-resistant Staphylococcus aureus (MRSA) strains with minimum inhibitory concentrations (MICs) ranging from1.9 to 3.9 microg/ml. 6-Methoxydihydrosanguinarine shows a dose-dependent effect at 1-10 microM on causing apoptotic cell death in HT29 colon carcinoma cells (IC50 = 5.0+/-0.2 microM). It also shows strong nematocidal activities, however, it is highly cytotoxic; thus, the prospect of its direct application is low.

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BP2131-100mg	100mg	Sign in	Sign in

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Related diseases

Inflammatory disease Breast cancer Colon cancer Antibacterial Glioma

Related targets

Inflammatory disease MAPK1 TNF PIK3CA PTGS2 NFKB1 AKT1 IL6 CTNNB1 MTOR

Breast cancer BCL2 MAPK1 ESR1 PIK3CA EGFR PTGS2 TP53 NFKB1 AKT1 CTNNB1 MTOR ERBB2

Colon cancer BCL2 MAPK1 TNF PIK3CA EGFR PTGS2 TP53 NFKB1 AKT1 CTNNB1 PDGFRA KRAS MTOR

Antibacterial MECA ERBB2 PBP2A FEMA SRTB VRA

Glioma BCL2 MAPK1 TNF PIK3CA EGFR TP53 NFKB1 AKT1 PDGFRA MTOR

Product description Related Products Prediction Parameters Reference Literature

Product name: 6-Methoxydihydrosanguinarine
Synonym name: (±)-6-Methoxyldihydrosanguinarine；(±)-8-Methoxydihydrosanguinarine；CAS:88544-84-7
Catalogue No.: BP2131
Cas No.: 72401-54-8
Formula: C₂₁H₁₇NO₅
Mol Weight: 363.369
Botanical Source: Macleaya cordata (Willd.) R. Br.
Type of Compound: Alkaloids

Purity: 95%~99%
Analysis Method: HPLC-DAD or/and HPLC-ELSD
Identification Method: Mass, NMR
Packing: Brown vial or HDPE plastic bottle

Storage: Store in a well closed container, protected from air and light. Put into refrigerate or freeze for long term storage.
Whenever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20℃. Generally, these will be useable for up to two weeks.

The product could be supplied from milligrams to grams
Inquire for bulk scale.

For Reference Standard and R&D, Not for Human Use Directly.