Crocin IV

Name: Crocin IV
Brand: Biopurify
Rating: 5 (1 reviews)

Catalogue No.： BP4121

CAS NO.: 57710-64-2

Purity: 98%

Brand: Biopurify

Botanical Source:

Crocin is a water-soluble carotenoid pigment of saffron (Crocus sativus L.), it has been used as a spice for flavoring and coloring food preparations. Crocin has anti-inflammatory, anti-oxidative, anti-apoptotic, anti-asthma, anti-cancer, and hypolipidemic effects. Crocin improves toxic effects of diazinon via reducing lipid peroxidation and restoring altered contractile and relaxant responses in rat aorta; it also protects retinal photoreceptors against light-induced cell death. Crocin can also promote ovarian cancer HO-8910 cell apoptosis, most likely by increasing p53 and Fas/APO-1 expression, and then activating the apoptotic pathway regulated by Caspase-3. Bis(beta-D-glucosyl) crocetin is a diester resulting from the formal condensation of each of the carboxylic acid groups of crocetin with an anomeric hydroxy group of beta-D-glucopyranose. It is a beta-D-glucoside and a diester. It is functionally related to a beta-D-glucose and a crocetin.

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Related diseases

Atherosclerosis Alzheimer's Disease Antioxidation Depression

Related targets

Atherosclerosis LOX-1 NFE2L2 HMGCR PPARG MMP9 NFKB1 NRF2 CAT HMOX1 ICAM1 VEGFA BDNF

Alzheimer's Disease BACE1 MAPT NFE2L2 HMGCR ACHE PPARG MMP9 NFKB1 SLC6A4 HTR1A NRF2 CAT GPX1 HMOX1 SOD2 BDNF GRIN1

Antioxidation NFE2L2 NRF2 CAT GPX1 HMOX1 SOD2

Depression NFE2L2 ACHE NR3C1 PPARG NFKB1 SLC6A4 HTR1A HMOX1 BDNF GRIN1

Product description Related Products Prediction Parameters Reference Literature

Product name: Crocin IV
Synonym name: Crocetin diglucosyl ester; Crocin 4
Catalogue No.: BP4121
Cas No.: 57710-64-2
Formula: C₃₂H₄₄O₁₄
Mol Weight: 652.69
Botanical Source: Crocus sativus L.
Type of Compound: Diterpenoids

Purity: 95%~99%
Analysis Method: HPLC-DAD or/and HPLC-ELSD
Identification Method: Mass, NMR
Packing: Brown vial or HDPE plastic bottle

Storage: Store in a well closed container, protected from air and light. Put into refrigerate or freeze for long term storage.
Whenever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20℃. Generally, these will be useable for up to two weeks.

The product could be supplied from milligrams to grams
Inquire for bulk scale.

Chengdu Biopurify Phytochemicals Ltd. is a leading company in the research, development, manufacture and marketing of High Quality Phytochemicals and Extracts(especially Active Ingredients from Traditional Chinese Medicine，TCM), Natural Active Pharmaceutical Ingredients worldwide.
The main services:
A. Supply active ingredients and reference standards of TCM, from mgs to kgs scale
B. Custom extraction and purification, target Herb Active Ingredients
C. Custom synthesis and semi-synthesis for Natural Active Ingredients
D. CR(contract research), CM(contract manufacture) and PD(process development) services from lab scale, pilot scale to commercial scale(GMP is also available)
E. TCM compounds library for drug screen,more than 3000 compounds available, many of them are rare and unique.