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Gigantol

BP3717
67884-30-4
98%
Biopurify
Dendrobii caulis
Gigantol is a novel inhibitor of the Wnt/β-catenin pathway, it inhibits Wnt/β-catenin signaling through downregulation of phosphorylated LRP6 and cytosolic β-catenin in breast cancer cells, it induces growth inhibition and apoptosis of HepG2 cells via the PI3K/Akt/NF-κB signaling pathway. Gigantol may be developed as a promising neuroprotective agent for successful MSC transplantation in ischemic diseases, it shows protective effect against hydrogen peroxide-induced apoptosis in rat bone marrow mesenchymal stem cells through the PI3K/Akt pathway. Gigantol inhibits aldose reductase gene to exert its anti-cataract activity. Gigantol also shows α-glucosidase inhibitory activity.
Catalog No Package Original Price Price Inventory Quantity Operating
BP3717-20mg 20mg
Chengdu Biopurify Phytochemicals Ltd.
Chengdu Biopurify Phytochemicals Ltd.

Related targets

PIK3CA NFKB1 AKT1 HMOX1 CTNNB1
NRF2 CAT GPX1 HMOX1 SOD2
PIK3CA NFKB1 AKT1 NRF2 GPX1 HMOX1 CTNNB1
PIK3CA AKT1
AKR1B1 CAT GPX1 HMOX1 SOD2

Product drug property prediction parameters

  • 58.9200

  • 3.0492

  • 3.0451

  • .2004

  • 7.5245

  • 5.4758

  • High

  • 91.6643

  • 1.9916

  • Yes

  • No

  • Yes

  • No

  • Yes

  • No

  • 0.0

  • No

  • No

  • No

  • No