Ilexgenin A

Name: Ilexgenin A
Brand: Biopurify
Rating: 5 (1 reviews)

Catalogue No.： BP1759

CAS NO.: 108524-94-3

Purity: 98%

Brand: Biopurify

Botanical Source: Ilex pubescens

Ilexgenin A exerts anti-inflammation and anti-angiogenesis effects through inhibition of STAT3 and PI3K pathways and exhibits synergistic effects with Sorafenib on hepatoma growth. It has anti-atherosclerotic activity, it shows reduction of atherosclerosis in apolipoprotein E deficient mice. Ilexgenin A is useful in the management of cardiovascular diseases in obesity, it inhibits endoplasmic reticulum stress and ameliorates endothelial dysfunction via suppression of TXNIP/NLRP3 inflammasome activation in an AMPK dependent manner. Ilexgenin A could be regarded as a promising agent for the treatment of melanoma, it exerts anti-melanoma activity by arresting the cell cycle at G0/G1 and regulating IL-6 and TNF-α production.

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Catalog No	Package	Original Price	Price
BP1759-5mg	5mg	Sign in	Sign in
BP1759-10mg	10mg	Sign in	Sign in
BP1759-20mg	20mg	Sign in	Sign in
BP1759-100mg	100mg	Sign in	Sign in

Contacts：400-829-7929，028-82633860，82633397，82633165

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Related diseases

Atherosclerosis Type 2 Diabetes Mellitus Non-alcoholic fatty liver disease Rheumatoid arthritis Colorectal Cancer

Related targets

Atherosclerosis PTPN1 BCL2 AMPK NFE2L2 TNF NOS2 PPARG MMP9 SREBF1 PTGS2 NFKB1 CASP3 IL6 IL1B BAX PPARA

Type 2 Diabetes Mellitus PTPN1 AMPK NFE2L2 TNF NOS2 PPARG SREBF1 PTGS2 NFKB1 IL6 IL1B IRS1 SLC2A4 PPARA

Non-alcoholic fatty liver disease PTPN1 AMPK NFE2L2 TNF NOS2 PPARG SREBF1 PTGS2 NFKB1 CASP3 IL6 IL1B IRS1 SLC2A4 PPARA

Rheumatoid arthritis BCL2 AMPK NFE2L2 TNF NOS2 PPARG MMP9 PTGS2 NFKB1 CASP3 IL6 IL1B IL17A

Colorectal Cancer BCL2 AMPK NFE2L2 TNF NOS2 PPARG MMP9 PTGS2 NFKB1 CASP3 IL6 BAX CDKN1A PPARA

Product description Related Products Prediction Parameters Reference Literature

Product name: Ilexgenin A
Synonym name:
Catalogue No.: BP1759
Cas No.: 108524-94-3
Formula: C₃₀H₄₆O₆
Mol Weight: 502.692
Botanical Source:
Type of Compound:

Purity: 95%~99%
Analysis Method: HPLC-DAD or/and HPLC-ELSD
Identification Method: Mass, NMR
Packing: Brown vial or HDPE plastic bottle

Storage: Store in a well closed container, protected from air and light. Put into refrigerate or freeze for long term storage.
Whenever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20℃. Generally, these will be useable for up to two weeks.

The product could be supplied from milligrams to grams
Inquire for bulk scale.

For Reference Standard and R&D, Not for Human Use Directly.

Storage conditions：Short-term storage at 2~8℃, long-term storage at -20 ~ -80℃