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Epiberberine

BP0537
6873-09-2
98%
Biopurify
Epiberberine, a natural protoberberine alkaloid, is a potent inhibitor against both ureases with IC50 values of 3.0±0.01μM for HPU (ureases from Helicobacter pylori) and 2.3±0.01μM for JBU (ureases from jack bean); it also exhibits predominant cholinesterases (ChEs) inhibitory effects with IC(50) values ranging between 0.44-1.07 microM for AChE and 3.32-6.84 microM for BChE. Epiberberine has anti-adipogenic effect is mediated by downregulation of the Raf/MEK1/ERK1/2 and AMPKα/Akt pathways during 3T3-L1 adipocyte differentiation. Epiberberine also ha anti-alzheimer and antioxidant activities.
Catalog No Package Original Price Price Inventory Quantity Operating
BP0537-20mg 20mg
BP0537-100mg 100mg
Chengdu Biopurify Phytochemicals Ltd.
Chengdu Biopurify Phytochemicals Ltd.

Related targets

BACE1 AMPK NFE2L2 BCHE GSK3B ACHE PPARG AKT1 HMOX1
AMPK NFE2L2 GSK3B PPARG AKT1 MAP2K1 HMOX1 FASN
GYRA GYPB DHFR MECA PENA
NFE2L2 PPARG AKT1 HMOX1

Product drug property prediction parameters

  • 40.8000

  • .2153

  • .2153

  • .3192

  • 2.9741

  • 29.5393

  • High

  • 24.7933

  • 2.8423

  • Yes

  • No

  • Yes

  • No

  • Yes

  • Yes

  • 2.4

  • No

  • No

  • No

  • No

Epiberberine Reference LiteratureMORE+