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Product name: Saikosaponin B2
Synonym name:
Catalogue No.: BP1240
Cas No.: 58316-41-9
Formula: C42H68O13
Mol Weight: 780.993
Botanical Source: Bupleurum falcatum
Physical Description: Powder
Type of Compound: Triterpenoids
Purity: 95%~99%
Analysis Method: HPLC-DAD or/and HPLC-ELSD
Identification Method: Mass, NMR
Packing: Brown vial or HDPE plastic bottle
Storage: Store in a well closed container, protected from air and light. Put into refrigerate or freeze for long term storage.
Whenever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20℃. Generally, these will be useable for up to two weeks.
The product could be supplied from milligrams to grams, up to kilograms
Inquire for bulk scale.
Descriptions:
Saikosaponin B2(SSb2) is an efficient inhibitor of early entry, including neutralization of virus particles, preventing viral attachment, and inhibiting viral entry/fusion, SSb2 may be of value for development as an antagonist of entry and could be explored as prophylactic treatment during the course of liver transplantation.[1]
Saikosaponin B2 can induce differentiation and apoptosis in cultured b16 melanoma cell line: 347.[2]
Saikosaponin B2 induces apoptosis of cultured B16 melanoma cell line through down-regulation of PKC activity.[3]
References:
[1] Lin L T, Chung C Y, Hsu W C, et al. J Hepatol, 2015, 62(3):541–8.
[2] Zong Z P, Fujikawa-Yamamoto K, Tanino M, et al. Melanoma Res, 1997, 7(7).
[3] Zong Z P, Fujikawa-Yamamoto K, Tanino M, et al.Biochem Bioph Res Co, 1996, 219(2):480-5.
[4] Jun L I, Jiang H, Zhang Y P, et al.Chinese Pharm J, 2011, 46(1):61-3.
HPLC of Saikosaponin B2
HNMR of Saikosaponin B2
Storage conditions：Short-term storage at 2~8℃, long-term storage at -20 ~ -80℃
218.9900
2.7152
2.7151
.0436
.5777
.5870
Low
72.6527
6.0658
No
No
No
No
No
No
0.0
Yes
No
No
Yes
Shenshuai
Wenjing
Hedandan
